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01-06-2021 | Echocardiography | Editorial

Low-dose gated bloodpool SPECT: Is it time to make the shift?

Authors: Laetitia Imbert, PhD, Pierre-Yves Marie, MD, PhD

Published in: Journal of Nuclear Cardiology | Issue 3/2021

Excerpt

Left ventricular radionuclide angiography (RNA) has been extensively used in the past for the assessment of prognosis and therapy in various ischemic and non-ischemic cardiomyopathies. In these indications, however, RNA has been progressively replaced by other cardiac imaging modalities, in particular by echocardiography. From a practical standpoint, most planar RNA are nowadays performed for the serial monitoring of left ventricular ejection fraction (LVEF) in patients with potentially cardiotoxic chemotherapies,1 even though echocardiography is also the most widely accepted imaging method in this indication.2,3 …

Kahanda MG, Hanson CA, Patterson B, Bourque JM. Nuclear cardio-oncology: From its foundation to its future. J Nucl Cardiol 2019. https://doi.org/10.1007/s12350-019-01655-6.CrossRefPubMed

Plana JC, Galderisi M, Barac A, Ewer MS, Ky B, Scherrer-Crosbie M, et al. Expert consensus for multimodality imaging evaluation of adult patients during and after cancer therapy: A report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging 2014;15:1063-93.CrossRef

Zamorano JL, Lancellotti P, Rodriguez Muñoz D, Aboyans V, Asteggiano R, Galderisi M, et al. 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines: The Task Force for cancer treatments and cardiovascular toxicity of the European Society of Cardiology (ESC). Eur J Heart Fail 2017;19:9-42.CrossRef

Sachpekidis C, Sachpekidis V, Moralidis E, Arsos G. Equilibrium radionuclide ventriculography: Still a clinically useful method for the assessment of cardiac function? Hell J Nucl Med 2018;21:213-22.PubMed

Hendel RC, Berman DS, Di Carli MF, Heidenreich PA, Henkin RE, Pellikka PA. ACCF/ASNC/ACR/AHA/ASE/SCCT/SCMR/SNM 2009 Appropriate use criteria for cardiac radionuclide imaging: A report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the American Society of Nuclear Cardiology, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the Society of Cardiovascular Computed Tomography, the Society for Cardiovascular Magnetic Resonance, and the Society of Nuclear Medicine. J Am Coll Cardiol 2009;53:2201-29.CrossRef

Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JGF, Coats AJS, et al. 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: The task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J 2016;37:2129-200.CrossRef

Tantawy AA, Elmasry OA, Shaaban M, Toaima DN, El Shahat AM. Radionuclide ventriculography detects early anthracycline cardiotoxicity in children with Hodgkin lymphoma. J Pediatr Hematol Oncol 2011;33:e132-7.CrossRef

Basar EZ, Corapcioglu F, Babaoglu K, Anik Y, Gorur Daglioz G, Dedeoglu R. Are cardiac magnetic resonance imaging and radionuclide ventriculography good options against echocardiography for evaluation of anthracycline induced chronic cardiotoxicity in childhood cancer survivors? Pediatr Hematol Oncol 2014;31:237-52.CrossRef

Wood PW, Choy JB, Nanda NC, Becher H. Left ventricular ejection fraction and volumes: It depends on the imaging method. Echocardiography 2014;31:87-100.CrossRef

10.

Hoffmann R, Barletta G, von Bardeleben S, Vanoverschelde JL, Kasprzak J, Greis C, et al. Analysis of left ventricular volumes and function: A multicenter comparison of cardiac magnetic resonance imaging, cine ventriculography, and unenhanced and contrast-enhanced two-dimensional and three-dimensional echocardiography. J Am Soc Echocardiogr 2014;27:292-301.CrossRef

11.

Hesse B, Lindhardt TB, Acampa W, et al. EANM/ESC guidelines for radionuclide imaging of cardiac function. Eur J Nucl Med Mol Imaging 2008;35:851-85.CrossRef

12.

Tissot H, Roch V, Morel O, Veran N, Perrin M, Claudin M, Verger A, Karcher G, Marie PY, Imbert L. Left ventricular ejection fraction determined with the simulation of a very low-dose CZT-SPECT protocol and an additional count-calibration on planar radionuclide angiographic data. J Nucl Cardiol 2019. https://doi.org/10.1007/s12350-019-01619-w.CrossRefPubMed

13.

Imbert L, Perrin M, Verger A, Marie PY. Dose optimization for myocardial perfusion CZT-SPECT imaging: Why and how? Clin Transl Imaging 2015;4:13-20.CrossRef

14.

Carpeggiani C, Rossi G, Landi P, Michelassi C, Brambilla M, Cortigiani L. Long-term outcome and medical radiation exposure in patients hospitalized for cardiovascular disease. Int J Cardiol 2015;195:30-6.CrossRef

15.

Eisenberg MJ, Afilalo J, Lawler PR, Abrahamowicz M, Richard H, Pilote L. Cancer risk related to low-dose ionizing radiation from cardiac imaging in patients after acute myocardial infarction. CMAJ 2011;183:430-6.CrossRef

16.

Imbert L, Poussier S, Franken PR, Songy B, Verger A, Morel O, et al. Compared performance of high-sensitivity cameras dedicated to myocardial perfusion SPECT: A comprehensive analysis of phantom and human images. J Nucl Med 2012;53:1897-903.CrossRef

17.

Perrin M, Djaballah W, Moulin F, Claudin M, Veran N, Imbert L, et al. Stress-first protocol for myocardial perfusion SPECT imaging with semiconductor cameras: High diagnostic performances with significant reduction in patient radiation doses. Eur J Nucl Med Mol Imaging 2015;42:1004-11.CrossRef

18.

Sharir T, Pinskiy M, Pardes A, Rochman A, Prokhorov V, Kovalski G, et al. Comparison of the diagnostic accuracies of very low stress-dose with standard-dose myocardial perfusion imaging: Automated quantification of one-day, stress-first SPECT using a CZT camera. J Nucl Cardiol 2016;23:11-20.CrossRef

19.

Liu YH, Fazzone-Chettiar R, Sandoval V, Tsatkin V, Miller EJ, Sinusas AJ. New approach for quantification of left ventricular function from low-dose gated bloodpool SPECT: Validation and comparison with conventional methods in patients. J Nucl Cardiol 2019. https://doi.org/10.1007/s12350-019-01823-8.CrossRefPubMed

20.

Marie PY, Imbert L. Proposed volume-based methods for correcting the shift in left ventricular ejection fraction from blood-pool gated SPECT. J Nucl Cardiol 2019. https://doi.org/10.1007/s12350-019-01657-4.CrossRefPubMed

Title: Low-dose gated bloodpool SPECT: Is it time to make the shift?
Authors: Laetitia Imbert, PhD
Pierre-Yves Marie, MD, PhD
Publication date: 01-06-2021
Publisher: Springer International Publishing
Keywords: Echocardiography
Echocardiography
Published in: Journal of Nuclear Cardiology / Issue 3/2021
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-019-01872-z

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