Skip to main content
Top
Published in: Journal of Nuclear Cardiology 3/2016

01-06-2016 | Original Article

A study to quantify the effect of patient motion and develop methods to detect and correct for motion during myocardial perfusion imaging on a CZT solid-state dedicated cardiac camera

Authors: Shelley Redgate, BSc, MSc, David C. Barber, BA, MSc, PhD, John W. Fenner, BSc, PhD, Abdallah Al-Mohammad, MD, FRCP(Edin), FRCP(Lon), FESC, Jonathon C. Taylor, MEng, MSc, Michael B. Hanney, BSc, MSc, Wendy B. Tindale, MSc, PhD

Published in: Journal of Nuclear Cardiology | Issue 3/2016

Login to get access

Abstract

Background

Due to differences in the design and acquisition parameters on the solid-state CZT cardiac camera the effect of patient motion may vary compared to Anger cameras. This study evaluates the effect of motion, two new methods of three-dimensional (3D) motion detection and a method of motion correction.

Method

Phantom acquisitions were offset in the X, Y, and Z directions and combined to simulate different types of motion. Motion artifacts were identified using the total perfusion defect and blinded visual interpretation. Motion was detected by registering planar and reconstructed 30 second images, and corrected by summing the aligned reconstructed images. Validation was performed on phantom data. These techniques were then applied to 40 patient studies.

Results

Motion ≥10 mm and ≥60 seconds in duration introduced significant artifacts. There was no significant difference (P = .258) between the two methods of motion detection. Motion correction removed artifacts from 9/10 phantom simulations. Superior-inferior motion ≥8 mm was measured on 10% of patient studies, and 5% were affected by motion. Motion in the lateral and anterior-posterior directions was <8 mm.

Conclusion

Superior-inferior patient motion artifacts have been identified on myocardial perfusion images acquired on a CZT camera. Routine QC to identify studies with significant motion is recommended.
Literature
1.
go back to reference Botvinick EH, Zhu YY, O’Connell WJ, Dae MW. A quantitative assessment of patient motion and its effect on myocardial perfusion SPECT images. J Nucl Med 1993;34:303-10.PubMed Botvinick EH, Zhu YY, O’Connell WJ, Dae MW. A quantitative assessment of patient motion and its effect on myocardial perfusion SPECT images. J Nucl Med 1993;34:303-10.PubMed
2.
go back to reference Sorrell V, Figueroa B, Hansen CL. The “hurricane sign”: Evidence of patient motion artifact on cardiac single-photon emission computed tomographic imaging. J Nucl Cardiol 1996;3:86-8.CrossRefPubMed Sorrell V, Figueroa B, Hansen CL. The “hurricane sign”: Evidence of patient motion artifact on cardiac single-photon emission computed tomographic imaging. J Nucl Cardiol 1996;3:86-8.CrossRefPubMed
3.
go back to reference Cooper JA, Neumann PH, McCandless BK. Effect of patient motion on tomographic myocardial perfusion imaging. J Nucl Med 1992;33:1566–71.PubMed Cooper JA, Neumann PH, McCandless BK. Effect of patient motion on tomographic myocardial perfusion imaging. J Nucl Med 1992;33:1566–71.PubMed
4.
go back to reference Friedman J, Van Train K, Maddahi J, Rozanski A, Prigent F, Bietendorf J, et al. “Upward creep” of the heart: A frequent source of false-positive reversible defects during thallium-201 stress-redistribution SPECT. J Nucl Med 1989;30:1718-22.PubMed Friedman J, Van Train K, Maddahi J, Rozanski A, Prigent F, Bietendorf J, et al. “Upward creep” of the heart: A frequent source of false-positive reversible defects during thallium-201 stress-redistribution SPECT. J Nucl Med 1989;30:1718-22.PubMed
5.
go back to reference Matsumoto N, Berman DS, Kavanagh PB, Gerlach J, Hayes SW, Lewin HC, et al. Quantitative assessment of motion artifacts and validation of a new motion-correction program for myocardial perfusion SPECT. J Nucl Med 2001;42:687-94.PubMed Matsumoto N, Berman DS, Kavanagh PB, Gerlach J, Hayes SW, Lewin HC, et al. Quantitative assessment of motion artifacts and validation of a new motion-correction program for myocardial perfusion SPECT. J Nucl Med 2001;42:687-94.PubMed
6.
go back to reference Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, et al. EANM/ESC procedural guidelines for myocardial perfusion imaging in nuclear cardiology. Eur J Nucl Med Mol Imaging 2005;32:855-97.CrossRefPubMed Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, et al. EANM/ESC procedural guidelines for myocardial perfusion imaging in nuclear cardiology. Eur J Nucl Med Mol Imaging 2005;32:855-97.CrossRefPubMed
7.
go back to reference Strauss HW, Miller DD, Wittry MD, Cerqueira MD, Garcia EV, Iskandrian AS, et al. Procedure guideline for myocardial perfusion imaging 3.3. J Nucl Med Technol 2008;36:155-61.CrossRefPubMed Strauss HW, Miller DD, Wittry MD, Cerqueira MD, Garcia EV, Iskandrian AS, et al. Procedure guideline for myocardial perfusion imaging 3.3. J Nucl Med Technol 2008;36:155-61.CrossRefPubMed
8.
go back to reference Fitzgerald J, Danias P. Effect of motion on cardiac SPECT imaging: Recognition and motion correction. J Nucl Cardiol 2001;8:701-6.CrossRefPubMed Fitzgerald J, Danias P. Effect of motion on cardiac SPECT imaging: Recognition and motion correction. J Nucl Cardiol 2001;8:701-6.CrossRefPubMed
9.
go back to reference Volokh L, Lahat C, Binyamin E, Blevis I. Myocardial perfusion imaging with an ultra-fast cardiac SPECT camera—A phantom study. Nuclear Science Symposium Conference Record. Dresden: IEEE; 2008. p. 4636-9. Volokh L, Lahat C, Binyamin E, Blevis I. Myocardial perfusion imaging with an ultra-fast cardiac SPECT camera—A phantom study. Nuclear Science Symposium Conference Record. Dresden: IEEE; 2008. p. 4636-9.
10.
go back to reference Esteves FP, Raggi P, Folks RD, Keidar Z, Askew JW, Rispler S, et al. Novel solid-state-detector dedicated cardiac camera for fast myocardial perfusion imaging: Multicenter comparison with standard dual detector cameras. J Nucl Cardiol 2009;16:927-34.CrossRefPubMedPubMedCentral Esteves FP, Raggi P, Folks RD, Keidar Z, Askew JW, Rispler S, et al. Novel solid-state-detector dedicated cardiac camera for fast myocardial perfusion imaging: Multicenter comparison with standard dual detector cameras. J Nucl Cardiol 2009;16:927-34.CrossRefPubMedPubMedCentral
11.
go back to reference Buechel R, Herzog B, Husmann L, Burger I, Pazhenkottil A, Treyer V, et al. Ultrafast nuclear myocardial perfusion imaging on a new gamma camera with semiconductor detector technique: First clinical validation. Eur J Nucl Med Mol Imaging 2010;37:773-8.CrossRefPubMed Buechel R, Herzog B, Husmann L, Burger I, Pazhenkottil A, Treyer V, et al. Ultrafast nuclear myocardial perfusion imaging on a new gamma camera with semiconductor detector technique: First clinical validation. Eur J Nucl Med Mol Imaging 2010;37:773-8.CrossRefPubMed
12.
go back to reference Bocher M, Blevis IM, Tsukerman L, Shrem Y, Kovalski G, Volokh L. A fast cardiac gamma camera with dynamic SPECT capabilities: Design, system validation and future potential. Eur J Nucl Med Mol Imaging 2010;37:1887-902.CrossRefPubMedPubMedCentral Bocher M, Blevis IM, Tsukerman L, Shrem Y, Kovalski G, Volokh L. A fast cardiac gamma camera with dynamic SPECT capabilities: Design, system validation and future potential. Eur J Nucl Med Mol Imaging 2010;37:1887-902.CrossRefPubMedPubMedCentral
13.
go back to reference Herzog BA, Buechel RR, Katz R, Brueckner M, Husmann L, Burger IA, et al. Nuclear myocardial perfusion imaging with a cadmium-zinc-telluride detector technique: Optimized protocol for scan time reduction. J Nucl Med 2010;51:46-51.CrossRefPubMed Herzog BA, Buechel RR, Katz R, Brueckner M, Husmann L, Burger IA, et al. Nuclear myocardial perfusion imaging with a cadmium-zinc-telluride detector technique: Optimized protocol for scan time reduction. J Nucl Med 2010;51:46-51.CrossRefPubMed
14.
go back to reference Schillaci O, Danieli R. Dedicated cardiac cameras: A new option for nuclear myocardial perfusion imaging. Eur J Nucl Med Mol Imaging 2010;37:1706-9.CrossRefPubMed Schillaci O, Danieli R. Dedicated cardiac cameras: A new option for nuclear myocardial perfusion imaging. Eur J Nucl Med Mol Imaging 2010;37:1706-9.CrossRefPubMed
15.
go back to reference Garcia EV, Faber TL, Esteves FP. Cardiac dedicated ultrafast SPECT cameras: New designs and clinical implications. J Nucl Med 2011;52:210-7.CrossRefPubMed Garcia EV, Faber TL, Esteves FP. Cardiac dedicated ultrafast SPECT cameras: New designs and clinical implications. J Nucl Med 2011;52:210-7.CrossRefPubMed
16.
go back to reference Duvall W, Croft L, Ginsberg E, Einstein A, Guma K, George T, et al. Reduced isotope dose and imaging time with a high-efficiency CZT SPECT camera. J Nucl Cardiol 2011;18:847-57.CrossRefPubMed Duvall W, Croft L, Ginsberg E, Einstein A, Guma K, George T, et al. Reduced isotope dose and imaging time with a high-efficiency CZT SPECT camera. J Nucl Cardiol 2011;18:847-57.CrossRefPubMed
17.
go back to reference Barber DC, Hose DR. Automatic segmentation of medical images using image registration: Diagnostic and simulation applications. J Med Eng Technol 2005;29:53-63.CrossRefPubMed Barber DC, Hose DR. Automatic segmentation of medical images using image registration: Diagnostic and simulation applications. J Med Eng Technol 2005;29:53-63.CrossRefPubMed
18.
go back to reference Barber DC, Oubel E, Frangi AF, Hose DR. Efficient computational fluid dynamics mesh generation by image registration. Med Image Anal 2007;11:648-62.CrossRefPubMed Barber DC, Oubel E, Frangi AF, Hose DR. Efficient computational fluid dynamics mesh generation by image registration. Med Image Anal 2007;11:648-62.CrossRefPubMed
19.
go back to reference Slomka P, Nishina H, Berman D, Akincioglu C, Abidov A, Friedman J, et al. Automated quantification of myocardial perfusion SPECT using simplified normal limits. J Nucl Cardiol 2005;12:66-77.CrossRefPubMed Slomka P, Nishina H, Berman D, Akincioglu C, Abidov A, Friedman J, et al. Automated quantification of myocardial perfusion SPECT using simplified normal limits. J Nucl Cardiol 2005;12:66-77.CrossRefPubMed
20.
go back to reference Cerqueira MD, Weissman NJ, Dilsizian V, Jacobs AK, Kaul S, Laskey WK, et al. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart. Circulation 2002;105:539-42.CrossRefPubMed Cerqueira MD, Weissman NJ, Dilsizian V, Jacobs AK, Kaul S, Laskey WK, et al. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart. Circulation 2002;105:539-42.CrossRefPubMed
21.
go back to reference Kapur A, Latus K, Davies G, Dhawan R, Eastick S, Jarritt P, et al. A comparison of three radionuclide myocardial perfusion tracers in clinical practice: The ROBUST study. Eur J Nucl Med Mol Imaging 2002;29:1608-16.CrossRefPubMed Kapur A, Latus K, Davies G, Dhawan R, Eastick S, Jarritt P, et al. A comparison of three radionuclide myocardial perfusion tracers in clinical practice: The ROBUST study. Eur J Nucl Med Mol Imaging 2002;29:1608-16.CrossRefPubMed
22.
go back to reference Hindorf C, Oddstig J, Hedeer F, Hansson M, Jögi J, Engblom H. Importance of correct patient positioning in myocardial perfusion SPECT when using a CZT camera. J Nucl Cardiol 2014;21:695-702.CrossRefPubMed Hindorf C, Oddstig J, Hedeer F, Hansson M, Jögi J, Engblom H. Importance of correct patient positioning in myocardial perfusion SPECT when using a CZT camera. J Nucl Cardiol 2014;21:695-702.CrossRefPubMed
23.
go back to reference Karacalioglu AO, Jata B, Kilic S, Arslan N, Ilgan S, Ozguven MA. A physiologic approach to decreasing upward creep of the heart during myocardial perfusion imaging. J Nucl Med Technol 2006;34:215-9.PubMed Karacalioglu AO, Jata B, Kilic S, Arslan N, Ilgan S, Ozguven MA. A physiologic approach to decreasing upward creep of the heart during myocardial perfusion imaging. J Nucl Med Technol 2006;34:215-9.PubMed
24.
go back to reference Prigent FM, Hyun M, Berman DS, Rozanski A. Effect of motion on thallium-201 SPECT studies: A simulation and clinical study. J Nucl Med 1993;34:1845-50.PubMed Prigent FM, Hyun M, Berman DS, Rozanski A. Effect of motion on thallium-201 SPECT studies: A simulation and clinical study. J Nucl Med 1993;34:1845-50.PubMed
Metadata
Title
A study to quantify the effect of patient motion and develop methods to detect and correct for motion during myocardial perfusion imaging on a CZT solid-state dedicated cardiac camera
Authors
Shelley Redgate, BSc, MSc
David C. Barber, BA, MSc, PhD
John W. Fenner, BSc, PhD
Abdallah Al-Mohammad, MD, FRCP(Edin), FRCP(Lon), FESC
Jonathon C. Taylor, MEng, MSc
Michael B. Hanney, BSc, MSc
Wendy B. Tindale, MSc, PhD
Publication date
01-06-2016
Publisher
Springer US
Published in
Journal of Nuclear Cardiology / Issue 3/2016
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-015-0314-1

Other articles of this Issue 3/2016

Journal of Nuclear Cardiology 3/2016 Go to the issue

Nuclear cardiology in the literature

A selection of recent, original research papers