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Open Access 01-04-2015 | Review Article

Myocardial viability as integral part of the diagnostic and therapeutic approach to ischemic heart failure

Authors: Jeroen J. Bax, MD, PhD, Victoria Delgado, MD, PhD

Published in: Journal of Nuclear Cardiology | Issue 2/2015

Abstract

Chronic heart failure is a major public-health problem with a high prevalence, complex treatment, and high mortality. A careful and comprehensive analysis is needed to provide optimal (and personalized) therapy to heart failure patients. The main 4 non-invasive imaging techniques (echocardiography, magnetic resonance imaging, multi-detector-computed tomography, and nuclear imaging) provide information on cardiovascular anatomy and function, which form the basis of the assessment of the pathophysiology underlying heart failure. The selection of imaging modalities depends on the information that is needed for the clinical management of the patients: (1) underlying etiology (ischemic vs non-ischemic); (2) in ischemic patients, need for revascularization should be evaluated (myocardial ischemia/viability?); (3) left ventricular function and shape assessment; (4) presence of significant secondary mitral regurgitation; (5) device therapy with cardiac resynchronization therapy and/or implantable cardiac defibrillator (risk of sudden cardiac death). This review is dedicated to assessment of myocardial viability, however “isolated assessment of myocardial viability” may be clinically not meaningful and should be considered among all those different variables. This complete information will enable personalized treatment of the patient with ischemic heart failure.

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Title: Myocardial viability as integral part of the diagnostic and therapeutic approach to ischemic heart failure
Authors: Jeroen J. Bax, MD, PhD
Victoria Delgado, MD, PhD
Publication date: 01-04-2015
Publisher: Springer US
Published in: Journal of Nuclear Cardiology / Issue 2/2015
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-015-0096-5

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