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Published in: Advances in Therapy 1/2022

01-01-2022 | Dapagliflozin | Review

A Narrative Review of Chronic Kidney Disease in Clinical Practice: Current Challenges and Future Perspectives

Authors: Marc Evans, Ruth D. Lewis, Angharad R. Morgan, Martin B. Whyte, Wasim Hanif, Stephen C. Bain, Sarah Davies, Umesh Dashora, Zaheer Yousef, Dipesh C. Patel, W. David Strain

Published in: Advances in Therapy | Issue 1/2022

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Abstract

Chronic kidney disease (CKD) is a complex disease which affects approximately 13% of the world’s population. Over time, CKD can cause renal dysfunction and progression to end-stage kidney disease and cardiovascular disease. Complications associated with CKD may contribute to the acceleration of disease progression and the risk of cardiovascular-related morbidities. Early CKD is asymptomatic, and symptoms only present at later stages when complications of the disease arise, such as a decline in kidney function and the presence of other comorbidities associated with the disease. In advanced stages of the disease, when kidney function is significantly impaired, patients can only be treated with dialysis or a transplant. With limited treatment options available, an increasing prevalence of both the elderly population and comorbidities associated with the disease, the prevalence of CKD is set to rise. This review discusses the current challenges and the unmet patient need in CKD.
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Metadata
Title
A Narrative Review of Chronic Kidney Disease in Clinical Practice: Current Challenges and Future Perspectives
Authors
Marc Evans
Ruth D. Lewis
Angharad R. Morgan
Martin B. Whyte
Wasim Hanif
Stephen C. Bain
Sarah Davies
Umesh Dashora
Zaheer Yousef
Dipesh C. Patel
W. David Strain
Publication date
01-01-2022
Publisher
Springer Healthcare
Published in
Advances in Therapy / Issue 1/2022
Print ISSN: 0741-238X
Electronic ISSN: 1865-8652
DOI
https://doi.org/10.1007/s12325-021-01927-z

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