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Indian Journal of Hematology and Blood Transfusion
Published in: Indian Journal of Hematology and Blood Transfusion 1/2014

01-09-2014 | Case Report

Acute Cholecystitis in Thrombotic Thrombocytopenic Purpura

Authors: Avani Changela, Kinesh Changela, Hemangkumar Javaiya, Dipali Changela, Sarah Lee, Elizabeth Guevara

Published in: Indian Journal of Hematology and Blood Transfusion | Special Issue 1/2014

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Excerpt

Thrombotic thrombocytopenic purpura (TTP) is a highly fatal thrombotic microangiopathy. The clinical features characterize it are thrombocytopenia, microangiopathic hemolytic anemia, neurologic abnormalities, renal dysfunction, and fever. Secondary TTP has a broad range of etiologies and has been associated with a variety of medical conditions including infections, malignancies, pregnancy, autoimmune disorder, HIV, bone marrow transplant and drugs [1, 2]. We report here a case of TTP associated with acute cholecystitis. A review of the medical literature results in only one other published report of TTP occurring in association with cholecystitis [3]. …
Literature
1.
George JN, Vesely SK, Terrell DR (2004) The oklahoma thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) registry: a community perspective of patients with clinically diagnosed TTP-HUS. Semin Hematol 41(1):60–67PubMedCrossRef
2.
Change JC, El-Tarabily M, Gupta S (2000) Acute thrombotic thrombocytopenic purpura following abdominal surgeries: a report of three cases. J Clin Apher 15(3):176–179CrossRef
3.
Jacobs WA (1985) Acute thrombotic thrombocytopenic purpura and cholecystitis. J Emerg Med 2(4):265–269PubMedCrossRef
4.
Booth KK, Terrell DR, Vesely SK, George JN (2001) ) Systemic infections mimicking thrombotic thrombocytopenic purpura. Am J Hematol 86(9):743–751CrossRef
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Claus RA, Bockmeyer CL, Sossdorf M, Losche W (2010) The balance between von-willebrand factor and its cleaving protease ADAMTS13: biomaker in systemic inflammation and development of organ failure? Curr Mol Med 10(2):236–248PubMedCrossRef
Metadata
Title
Acute Cholecystitis in Thrombotic Thrombocytopenic Purpura
Authors
Avani Changela
Kinesh Changela
Hemangkumar Javaiya
Dipali Changela
Sarah Lee
Elizabeth Guevara
Publication date
01-09-2014
Publisher
Springer India
Published in
Indian Journal of Hematology and Blood Transfusion / Issue Special Issue 1/2014
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI
https://doi.org/10.1007/s12288-014-0361-9

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