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Published in: Journal of Cardiovascular Translational Research 4/2012

01-08-2012

The Clinical Relevance of the Clopidogrel–Proton Pump Inhibitor Interaction

Authors: Atif Mohammad, Emmanouil S. Brilakis, Rick A. Weideman, Bertis B. Little, Subhash Banerjee

Published in: Journal of Cardiovascular Translational Research | Issue 4/2012

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Abstract

Proton pump inhibitors are often prescribed concomitantly with clopidogrel and aspirin to patients post-percutaneous coronary interventions and/or an acute coronary syndrome to mitigate the risk of potential gastrointestinal bleeding, associated primarily with clopidogrel use. Over the last several years, there have been data both supporting and refuting a clopidogrel–proton pump inhibitor interaction. This review critically considers the current evidence and provides practical recommendations to healthcare providers.
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Metadata
Title
The Clinical Relevance of the Clopidogrel–Proton Pump Inhibitor Interaction
Authors
Atif Mohammad
Emmanouil S. Brilakis
Rick A. Weideman
Bertis B. Little
Subhash Banerjee
Publication date
01-08-2012
Publisher
Springer US
Published in
Journal of Cardiovascular Translational Research / Issue 4/2012
Print ISSN: 1937-5387
Electronic ISSN: 1937-5395
DOI
https://doi.org/10.1007/s12265-011-9334-7

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