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memo - Magazine of European Medical Oncology

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01-09-2021 | Magnetic Resonance Imaging | case report

Primary diffuse leptomeningeal melanomatosis: report of three pediatric cases and review of the literature

Authors: Giovanna Pezzullo, MD, Lorenzo Ugga, Renato Cuocolo, Teresa Perillo, Alessandra D’Amico

Published in: memo - Magazine of European Medical Oncology | Issue 3/2021

Summary

Primary diffuse leptomeningeal melanomatosis is a rare and very aggressive neoplasm with only 6 pediatric cases reported so far. Recognizing this condition is unfortunately difficult due to the nonspecific clinical presentation. Nevertheless, imaging may help in a timely diagnosis that can better direct the management of these patients, especially in the light of the rapidly ominous course of the pathology. We describe three cases of pediatric primary diffuse leptomeningeal melanomatosis and review the literature regarding this entity, focusing on computed tomography and magnetic resonance imaging findings.

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Title: Primary diffuse leptomeningeal melanomatosis: report of three pediatric cases and review of the literature
Authors: Giovanna Pezzullo, MD
Lorenzo Ugga
Renato Cuocolo
Teresa Perillo
Alessandra D’Amico
Publication date: 01-09-2021
Publisher: Springer Vienna
Keywords: Magnetic Resonance Imaging
Magnetic Resonance Imaging
Computed Tomography
Autopsy
Melanoma
Melanoma
Computed Tomography
Hydrocephalus
Hydrocephalus
Vomiting
Hydrocephalus
Headache
Published in: memo - Magazine of European Medical Oncology / Issue 3/2021
Print ISSN: 1865-5041
Electronic ISSN: 1865-5076
DOI: https://doi.org/10.1007/s12254-021-00720-6

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