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Published in: Annals of Nuclear Medicine 8/2020

01-08-2020 | Metastasis | Original Article

Detectable size of melanoma metastases to brain on PET/CT

Authors: Jorge D. Oldan, Samuel A. Glaubiger, Amir H. Khandani, Valerie L. Jewells

Published in: Annals of Nuclear Medicine | Issue 8/2020

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Abstract

Objective

We aimed to determine at what size melanoma metastases become detectable by PET/CT.

Methods

We reviewed a total of 293 whole-body PET/CT studies performed on 212 patients for staging of melanoma where there was an MRI within a month of the PET/CT. MR and PET/CT were reviewed independently by separate readers.

Results

PET/CT revealed an overall incidental true-positive rate of 1% on a per-patient basis, consistent with other studies, with ‘hot’ lesions (more avid than brain parenchyma) visible at smaller sizes than ‘cold’ lesions.

Conclusions

PET/CT can detect metastatic melanoma lesions over about 2 cm in size, with hot lesions generally visible at smaller sizes.
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Metadata
Title
Detectable size of melanoma metastases to brain on PET/CT
Authors
Jorge D. Oldan
Samuel A. Glaubiger
Amir H. Khandani
Valerie L. Jewells
Publication date
01-08-2020
Publisher
Springer Singapore
Published in
Annals of Nuclear Medicine / Issue 8/2020
Print ISSN: 0914-7187
Electronic ISSN: 1864-6433
DOI
https://doi.org/10.1007/s12149-020-01481-8

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