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Annals of Nuclear Medicine
Published in: Annals of Nuclear Medicine 5/2018

01-06-2018 | Original Article

Implementation of GPU accelerated SPECT reconstruction with Monte Carlo-based scatter correction

Authors: Tobias Bexelius, Antti Sohlberg

Published in: Annals of Nuclear Medicine | Issue 5/2018

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Abstract

Objective

Statistical SPECT reconstruction can be very time-consuming especially when compensations for collimator and detector response, attenuation, and scatter are included in the reconstruction. This work proposes an accelerated SPECT reconstruction algorithm based on graphics processing unit (GPU) processing.

Methods

Ordered subset expectation maximization (OSEM) algorithm with CT-based attenuation modelling, depth-dependent Gaussian convolution-based collimator-detector response modelling, and Monte Carlo-based scatter compensation was implemented using OpenCL. The OpenCL implementation was compared against the existing multi-threaded OSEM implementation running on a central processing unit (CPU) in terms of scatter-to-primary ratios, standardized uptake values (SUVs), and processing speed using mathematical phantoms and clinical multi-bed bone SPECT/CT studies.

Results

The difference in scatter-to-primary ratios, visual appearance, and SUVs between GPU and CPU implementations was minor. On the other hand, at its best, the GPU implementation was noticed to be 24 times faster than the multi-threaded CPU version on a normal 128 × 128 matrix size 3 bed bone SPECT/CT data set when compensations for collimator and detector response, attenuation, and scatter were included.

Conclusions

GPU SPECT reconstructions show great promise as an every day clinical reconstruction tool.
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Metadata
Title
Implementation of GPU accelerated SPECT reconstruction with Monte Carlo-based scatter correction
Authors
Tobias Bexelius
Antti Sohlberg
Publication date
01-06-2018
Publisher
Springer Japan
Published in
Annals of Nuclear Medicine / Issue 5/2018
Print ISSN: 0914-7187
Electronic ISSN: 1864-6433
DOI
https://doi.org/10.1007/s12149-018-1252-1

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