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Medical Oncology
Published in: Medical Oncology 1/2017

01-01-2017 | Original Paper

The role of interventional radiology in the treatment of intrahepatic cholangiocarcinoma

Authors: Anna Maria Ierardi, Salvatore Alessio Angileri, Francesca Patella, Silvia Panella, Natalie Lucchina, Elena N. Petre, Antonio Pinto, Giuseppe Franceschelli, Gianpaolo Carrafiello, Gianpaolo Cornalba, Constantinos T. Sofocleous

Published in: Medical Oncology | Issue 1/2017

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Abstract

Intrahepatic cholangiocarcinoma (ICC) is the second most common primary hepatic malignancy after hepatocellular carcinoma. Complete surgical resection remains the only potentially curative option for patients with ICC. However, until now, early diagnosis with potential surgical intervention has been the exception rather than the rule with only 30% of patients qualifying for attempted surgical cure. Many patients are unresectable because of disease stage, anatomic conditions, medical comorbidities, and small future remnant liver. Interventional radiology procedures are available for these types of patients with intra-arterial therapies and/or ablative treatments both for curative and for palliative treatment. The goals of interventional therapy are to control local tumor growth, to relieve symptoms, and to improve and preserve quality of life. The choice of treatment depends largely on tumor extent and patient performance. No randomized studies exist to compare treatments. The present review describes the current evidence of the interventional treatments in the management of the ICC. Moreover, interventional procedures available to increase the future liver reserve before surgery were analyzed.
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Metadata
Title
The role of interventional radiology in the treatment of intrahepatic cholangiocarcinoma
Authors
Anna Maria Ierardi
Salvatore Alessio Angileri
Francesca Patella
Silvia Panella
Natalie Lucchina
Elena N. Petre
Antonio Pinto
Giuseppe Franceschelli
Gianpaolo Carrafiello
Gianpaolo Cornalba
Constantinos T. Sofocleous
Publication date
01-01-2017
Publisher
Springer US
Published in
Medical Oncology / Issue 1/2017
Print ISSN: 1357-0560
Electronic ISSN: 1559-131X
DOI
https://doi.org/10.1007/s12032-016-0866-1

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