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01-09-2012 | Short Communication

Absence of human papillomavirus sequences in epithelial breast cancer in a Mexican female population

Published in: Medical Oncology | Issue 3/2012

Abstract

The role of human papillomavirus (HPV) in breast cancer is controversial. We evaluated 118 breast carcinomas and two paraffin-embedded tissues of lesions of the nipple of Mexican patients for HPV sequences. No carcinoma sample exhibited koilocytosis, in contrast to lesions of the nipple. We subjected purified DNAs to PCR employing two HPV16/E6 or GP5/6 primer set oligonucleotides. Results showed that HPV DNA sequences were absent in the breast tissues. Absence of HPV in breast carcinoma failed to support an association between HPV infection and this carcinoma.

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Title: Absence of human papillomavirus sequences in epithelial breast cancer in a Mexican female population
Publication date: 01-09-2012
Published in: Medical Oncology / Issue 3/2012
Print ISSN: 1357-0560
Electronic ISSN: 1559-131X
DOI: https://doi.org/10.1007/s12032-011-0059-x

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