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Medical Oncology
Published in: Medical Oncology 4/2010

01-12-2010 | Original Paper

An unusual presentation of extramedullary plasmacytoma in testis and review of the literature

Authors: H. Mehmet Turk, Seref Komurcu, Ahmet Ozet, Okan Kuzhan, Ömer Günhan

Published in: Medical Oncology | Issue 4/2010

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Abstract

Extramedullary plasmacytoma is a rare plasma cell neoplasm, and it is extremely uncommon in the testicles. We report a 73-year-old man with multiple myeloma presented with testicular plasmacytoma. He complained of left leg pain and scrotal swelling. Ultrasonography revealed testicular masses. Pathologic examination of the orchiectomy specimen showed plasmocytoma with kappa expression. Multiple lytic bone lesions were seen in bone survey scans, serum immunoelectrophoresis and bone marrow aspiration aided to the diagnosis of multiple myeloma. He received chemotherapy, melphalan and prednisolone, and palliative radiotherapy. He succumbed to disease after 8 months.
Literature
1.
Soutar R, Lucraft H, Jackson G, Reece A, Bird J, Low E. Samson D; Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma. Br J Haematol. 2004;124(6):717–26.CrossRefPubMed
2.
Shih LY, Dunn P, Leung WM, Chen WJ, Wang PN. Localised plasmacytomas in Taiwan:comparison between extramedullary plasmacytoma and solitary plasmacytoma of bone. Br J Cancer. 1995;71(1):128–33.PubMed
3.
Alexiou C, Kau RJ, Dietzfelbinger H, Kremer M, Spiess JC, Schratzenstaller B, et al. Extramedullary plasmacytoma: tumor occurrence and therapeutic concepts. Cancer. 1999;85(11):2305–14.CrossRefPubMed
4.
Strojan P, Soba E, Lamovec J, Munda A. Extramedullary plasmacytoma: clinical and histopathologic study. Int J Radiat Oncol Biol Phys. 2002;53(3):692–701.CrossRefPubMed
5.
Kyte RA, Greipp PA. Plasma cell dyscrasias: current status. Crit Rev Oncol Hematol. 1998;8:93–152.
6.
Tsang RW, Gospodarowicz MK, Pintilie M, Bezjak A, Wells W, Hodgson DC, et al. Solitary plasmacytoma treated with radiotherapy impact of tumor size on outcome. Int J Radiat Oncol Biol Phys. 2001;50(1):113–20.CrossRefPubMed
7.
8.
Hayes DW, Bennett WA, Heck FJ. Extramedullary lesions in multiple myeloma; review of literature and pathologic studies. AMA Arch Pathol. 1952;53(3):262–72.PubMed
9.
Gowing NF. Malignant lymphoma of the testis. Br J Urol. 1964;36(Suppl):85–94.PubMed
10.
Chica G, Johnson DE, Ayala AG. Plasmacytoma of testis presenting as primary testicular tumor. Urology. 1978;11(1):90–2.CrossRefPubMed
11.
Oppenheim PI, Cohen S, Anders KH. Testicular plasmacytoma: a case report with immunohistochemical studies and literature review. Arch Pathol Lab Med. 1991;115(6):629–32.PubMed
12.
Anghel G, Petti N, Remotti D, Ruscio C, Blandino F, Majolino I. Testicular plasmacytoma: report of a case and review of the literature. Am J Hematol. 2002;71(2):98–104.CrossRefPubMed
13.
14.
Avitable AM, Gansler TS, Tomaszevski JE, Hanno P, Goldwein MI. Testicular plasmacytoma. Urology. 1989;34(1):51–4.CrossRefPubMed
15.
Mayr NA, Wen BC, Hussey DH, Burns CP, Staples JJ, Doornbos JF, et al. The role of radiation therapy in the treatment of solitary plasmacytoma. Radiother Oncol. 1990;17(4):293–303.CrossRefPubMed
Metadata
Title
An unusual presentation of extramedullary plasmacytoma in testis and review of the literature
Authors
H. Mehmet Turk
Seref Komurcu
Ahmet Ozet
Okan Kuzhan
Ömer Günhan
Publication date
01-12-2010
Publisher
Springer US
Published in
Medical Oncology / Issue 4/2010
Print ISSN: 1357-0560
Electronic ISSN: 1559-131X
DOI
https://doi.org/10.1007/s12032-009-9390-x

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