Published in:
01-06-2018 | Case Report
Long-Term Survival with Chemoradiation Alone in Locally Advanced Unresectable Gallbladder Cancer: First Case Report of a New Paradigm
Author:
Sushma Agrawal
Published in:
Journal of Gastrointestinal Cancer
|
Issue 2/2018
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Excerpt
Gallbladder cancer (GBC) is endemic in North India in the Indo-Gangetic belt and usually presents as unresectable or metastatic disease [
1]. Palliative chemotherapy is the only treatment which yields a median survival of 9 months [
2]. Unresectable GBCs are those which are involving the portal vein, hepatic artery, or contiguous organs and those with distant nodal disease or metastases. Attempt at neoadjuvant strategies in non-metastatic locally advanced gallbladder cancer shows resectability rates ranging from 15–40% [
3,
4]. Survival beyond 25 months has not been reported with this strategy. We report the first case with 8-year-survival after chemoradiation in a woman with locally advanced gallbladder cancer. …