Published in:
01-03-2017 | Case Report
A Case of Signet Ring Cell Carcinoma of the Gallbladder Which Was Treated by Aggressive Surgery and Intensive Adjuvant Chemotherapy
Authors:
Masatsugu Hiraki, Junji Ueda, Keita Kai, Takao Ide, Masako Asai, Takao Ohtsuka, Naohiko Kohya, Shinsuke Mukai, Kenji Kitahara, Hirokazu Noshiro
Published in:
Journal of Gastrointestinal Cancer
|
Issue 1/2017
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Excerpt
Carcinoma of the gallbladder is the most common malignancy of the biliary tract. It is a highly fatal disease with a poor prognosis [
1]. Intensive treatment, including surgery and effective chemotherapy, is therefore important for prolonging patient survival. Adenocarcinoma is the most common histological type of gallbladder carcinoma (80–95 %) [
1], while signet ring cell carcinoma (SRCC) is extremely rare. In the digestive system, SRCC mostly occurs in the stomach (86.8 %). SRCC of the gallbladder is extremely rare (2.5 %) [
2,
3]. As a result, the biological features and treatment strategies have not been well documented due to the small number of previous reports. In the present study, we report the case of a patient with gallbladder SRCC who was treated with aggressive surgery and intensive adjuvant chemotherapy using gemcitabine and S-1. …
