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Published in: Current Urology Reports 8/2014

01-08-2014 | Pediatric Urology (M Castellan and R Gosalbez, Section Editors)

Prenatal Hydronephrosis: Postnatal Evaluation and Management

Authors: Vijaya Vemulakonda, Jenny Yiee, Duncan T. Wilcox

Published in: Current Urology Reports | Issue 8/2014

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Abstract

Congenital hydronephrosis is one of the most common anomalies identified on antenatal ultrasound. The underlying etiology of congenital hydronephrosis is multifold, ranging from transient hydronephrosis in utero to clinically significant congenital anomalies of the kidney and urinary tract. While traditional management of hydronephrosis was aimed at relieving symptoms, the advent of routine prenatal ultrasound has led to a shift in the goal of treatment to prevention of renal injury in the asymptomatic patient. However, despite this focus on renal preservation, the diagnostic criteria for identification of children “at risk” for renal damage that can be alleviated by surgical treatment remain a subject of debate. Both antenatal and postnatal imaging studies have been evaluated as indicators for potential reversible renal damage and have been used as potential indicators of the need for surgical intervention. The aim of this review is to discuss the current literature regarding the role of postnatal clinical and radiographic evaluation to identify children who may benefit from early surgical intervention.
Literature
1.
go back to reference Sutherland R, Chung S, Roth D, Gonzales E. Pediatric pyeloplasty: outcome analysis based on patient age and surgical technique. Urology. 1997;50:963–6.PubMedCrossRef Sutherland R, Chung S, Roth D, Gonzales E. Pediatric pyeloplasty: outcome analysis based on patient age and surgical technique. Urology. 1997;50:963–6.PubMedCrossRef
2.
3.
go back to reference Adra A, Mejides A, Dennaoui M, Beydoun S. Fetal pyelectasis: is it always “physiologic”? Am J Obstet Gynecol. 1995;173:1263–6.PubMedCrossRef Adra A, Mejides A, Dennaoui M, Beydoun S. Fetal pyelectasis: is it always “physiologic”? Am J Obstet Gynecol. 1995;173:1263–6.PubMedCrossRef
4.•
go back to reference Ismaili K, Hall M, Donner C, Thomas D, Vermeylen D, Avni F. Results of systematic screening for minor degress of fetal renal pelvis dilatation in an unselected population. Am J Obstet Gynecol. 2003;188:242–6. This article is a prospective cohort study that established the AP diameter cut off of 7 mm as a predictor of post-natal pathology. PubMedCrossRef Ismaili K, Hall M, Donner C, Thomas D, Vermeylen D, Avni F. Results of systematic screening for minor degress of fetal renal pelvis dilatation in an unselected population. Am J Obstet Gynecol. 2003;188:242–6. This article is a prospective cohort study that established the AP diameter cut off of 7 mm as a predictor of post-natal pathology. PubMedCrossRef
5.•
go back to reference Lee R, Cendron M, Kinnamon D, Nguyen H. Antenatal hydronephrosis as a predictor of postnatal outcome: a meta-analysis. Pediatrics. 2006;118:586–93. This meta-analysis of antenatal hydronephrosis and postnatal pathology established the relative risk of vesicoureteral reflux, ureteropelvic junction obstruction, and other postnatal diagnoses based on degree of antenatal dilation. Lee R, Cendron M, Kinnamon D, Nguyen H. Antenatal hydronephrosis as a predictor of postnatal outcome: a meta-analysis. Pediatrics. 2006;118:586–93. This meta-analysis of antenatal hydronephrosis and postnatal pathology established the relative risk of vesicoureteral reflux, ureteropelvic junction obstruction, and other postnatal diagnoses based on degree of antenatal dilation.
6.
go back to reference Ismaili K, Avni F, Piepsz A, Wissing K, Cochat P, Aubert D, et al. Current management of infants with fetal renal pelvis dilation: a survey by French-speaking pediatric nephrologists and urologists. Pediatr Nephrol. 2004;19:966–71.PubMedCrossRef Ismaili K, Avni F, Piepsz A, Wissing K, Cochat P, Aubert D, et al. Current management of infants with fetal renal pelvis dilation: a survey by French-speaking pediatric nephrologists and urologists. Pediatr Nephrol. 2004;19:966–71.PubMedCrossRef
7.
go back to reference Sidhu G, Beyene J, Rosenblum N. Outcome of isolated antenatal hydronephrosis: a sytematic review and meta-analysis. Pediatr Nephrol. 2006;21:218–24.PubMedCrossRef Sidhu G, Beyene J, Rosenblum N. Outcome of isolated antenatal hydronephrosis: a sytematic review and meta-analysis. Pediatr Nephrol. 2006;21:218–24.PubMedCrossRef
8.
go back to reference Nguyen HT, Herndon CD, Cooper C, Gatti J, Kirsch A, Kokorowski P, et al. The Society for Fetal Urology consensus statement on the evaluation and management of antenatal hydronephrosis. J Pediatr Urol. 2010;6(3):212–31.PubMedCrossRef Nguyen HT, Herndon CD, Cooper C, Gatti J, Kirsch A, Kokorowski P, et al. The Society for Fetal Urology consensus statement on the evaluation and management of antenatal hydronephrosis. J Pediatr Urol. 2010;6(3):212–31.PubMedCrossRef
9.
go back to reference Ciardelli V, Rizzo N, Farina A, Vitarelli M, Boni P, Bovicelli L. Prenatal evaluation of fetal renal function based on serum beta(2)-microglobulin assessment. Prenat Diagn. 2001;21(7):586–8.PubMedCrossRef Ciardelli V, Rizzo N, Farina A, Vitarelli M, Boni P, Bovicelli L. Prenatal evaluation of fetal renal function based on serum beta(2)-microglobulin assessment. Prenat Diagn. 2001;21(7):586–8.PubMedCrossRef
10.
go back to reference Bokenkamp A, Dieterich C, Dressler F, Muhlhaus K, Gembruch U, Bald R. Kirschstein. Fetal serum concentrations of cystatin C and beta2-microglobulin as predictors of postnatal kidney function. Am J Obstet Gynecol. 2001;185(2):468–75.PubMedCrossRef Bokenkamp A, Dieterich C, Dressler F, Muhlhaus K, Gembruch U, Bald R. Kirschstein. Fetal serum concentrations of cystatin C and beta2-microglobulin as predictors of postnatal kidney function. Am J Obstet Gynecol. 2001;185(2):468–75.PubMedCrossRef
11.
go back to reference Morin LCM, Crombleholme TM, Garmel SH, Klauber GT, D'alton ME. Minimal hydronephrosis in the fetus: clinical significance and implications for I. J Urol. 1996;155:2047–9.PubMedCrossRef Morin LCM, Crombleholme TM, Garmel SH, Klauber GT, D'alton ME. Minimal hydronephrosis in the fetus: clinical significance and implications for I. J Urol. 1996;155:2047–9.PubMedCrossRef
12.
go back to reference Signorelli M, Cerri V, Taddei F, Groli C, Bianchi UA. Prenatal diagnosis and management of mild fetal pyelectasis: implications for neonatal outcome and follow-up. Eur J Obstet Gynecol Reprod Biol. 2005;118(2):154–9.PubMedCrossRef Signorelli M, Cerri V, Taddei F, Groli C, Bianchi UA. Prenatal diagnosis and management of mild fetal pyelectasis: implications for neonatal outcome and follow-up. Eur J Obstet Gynecol Reprod Biol. 2005;118(2):154–9.PubMedCrossRef
13.
go back to reference Wiener J, O'hara S. Optimal timing of initial postnatal ultrasonography in newborns with prenatal hydronephrosis. J Urol. 2002;168:1826–9.PubMedCrossRef Wiener J, O'hara S. Optimal timing of initial postnatal ultrasonography in newborns with prenatal hydronephrosis. J Urol. 2002;168:1826–9.PubMedCrossRef
14.
go back to reference Docimo S, Silver R. Renal ultrasonography in newborns with prenatally detected hydronephrosis: why wait? J Urol. 1997;157:1387–9.PubMedCrossRef Docimo S, Silver R. Renal ultrasonography in newborns with prenatally detected hydronephrosis: why wait? J Urol. 1997;157:1387–9.PubMedCrossRef
15.
go back to reference Hafez AT, McLorie G, Bagli D, Khoury A. Analysis of trends on serial ultrasound for high grade neonatal hydronephrosis. J Urol. 2002;168(4 pt 1):1518–21.PubMedCrossRef Hafez AT, McLorie G, Bagli D, Khoury A. Analysis of trends on serial ultrasound for high grade neonatal hydronephrosis. J Urol. 2002;168(4 pt 1):1518–21.PubMedCrossRef
16.
go back to reference Keays MA, Guerra LA, Mihill J, Raju G, Al-Asheeri N, Geier P, et al. Reliability assessment of Society for Fetal Urology ultrasound grading system for hydronephrosis. J Urol. 2008;180(4 Suppl):1680–2.PubMedCrossRef Keays MA, Guerra LA, Mihill J, Raju G, Al-Asheeri N, Geier P, et al. Reliability assessment of Society for Fetal Urology ultrasound grading system for hydronephrosis. J Urol. 2008;180(4 Suppl):1680–2.PubMedCrossRef
17.
18.
go back to reference Srivastava T, Betts G, Rosenberg A, Kainer G. Perception of fear, distress, and pain by parents of children undergoing a micturating cystourethrogram: a prospective studey. J Paediatr Child Health. 2001;37:271–3.PubMedCrossRef Srivastava T, Betts G, Rosenberg A, Kainer G. Perception of fear, distress, and pain by parents of children undergoing a micturating cystourethrogram: a prospective studey. J Paediatr Child Health. 2001;37:271–3.PubMedCrossRef
19.
go back to reference Riccabona M. Assement and management of newborn hydronephrosis. World J Urol. 2004;22:73–8.PubMed Riccabona M. Assement and management of newborn hydronephrosis. World J Urol. 2004;22:73–8.PubMed
20.
go back to reference Yerkes E, Adams M, Pope J, Brock J. Does every patient with hydronephrosis need voiding cystourethrography? J Urol. 1999;162:1218–20.PubMedCrossRef Yerkes E, Adams M, Pope J, Brock J. Does every patient with hydronephrosis need voiding cystourethrography? J Urol. 1999;162:1218–20.PubMedCrossRef
21.
go back to reference Ismaili KAF, Hall M. Results of systematic voiding cystourethrography in infants with antenatally diagnosed renal pelvis dilation. J Pediatr. 2002;141:21–4.PubMedCrossRef Ismaili KAF, Hall M. Results of systematic voiding cystourethrography in infants with antenatally diagnosed renal pelvis dilation. J Pediatr. 2002;141:21–4.PubMedCrossRef
22.
go back to reference Vemulakonda VM, Chiang G, Corbett ST. Variability in use of voiding cystourethrogram during initial evaluation of infants with congenital hydronephrosis. Urology. 2014;83(5):1135–8. Vemulakonda VM, Chiang G, Corbett ST. Variability in use of voiding cystourethrogram during initial evaluation of infants with congenital hydronephrosis. Urology. 2014;83(5):1135–8.
23.
go back to reference Ransley PGDH, Gordon I, Duffy PG, Dillon MJ, Barratt TM. The postnatal management of hydronehrosis diagnosed by prenatal ultrasound. J Urol. 1990;144:584–7.PubMed Ransley PGDH, Gordon I, Duffy PG, Dillon MJ, Barratt TM. The postnatal management of hydronehrosis diagnosed by prenatal ultrasound. J Urol. 1990;144:584–7.PubMed
24.
go back to reference Muller-Suur R, Tyden O. Evaluation of hydronephrosis in pregnancy using ultrasound and renography. Scand J Urol Nephrol. 1985;19(4):267–73.PubMedCrossRef Muller-Suur R, Tyden O. Evaluation of hydronephrosis in pregnancy using ultrasound and renography. Scand J Urol Nephrol. 1985;19(4):267–73.PubMedCrossRef
25.
go back to reference Kass EJ, Fink-Bennet D. Contemporary techniques for the radioisotopic evaluation of the dilated urinary tract. Urol Clin North Am. 1990;17(2):273–89.PubMed Kass EJ, Fink-Bennet D. Contemporary techniques for the radioisotopic evaluation of the dilated urinary tract. Urol Clin North Am. 1990;17(2):273–89.PubMed
26.
go back to reference Eskild-Jenson A, Gordon I, Piepsz A, Frokler J. Congenital unilateral hydronephrosis: a review of the impact of diuretic renography on clinical treatment. J Urol. 2005;173:1471–6.CrossRef Eskild-Jenson A, Gordon I, Piepsz A, Frokler J. Congenital unilateral hydronephrosis: a review of the impact of diuretic renography on clinical treatment. J Urol. 2005;173:1471–6.CrossRef
27.
go back to reference Karnak I, Woo LL, Shah SN, Sirajuddin A, Ross JH. Results of a practical protocol for management of prenatally detected hydronephrosis due to ureteropelvic junction obstruction. Pediatr Surg Int. 2009;25(1):61–7.PubMedCrossRef Karnak I, Woo LL, Shah SN, Sirajuddin A, Ross JH. Results of a practical protocol for management of prenatally detected hydronephrosis due to ureteropelvic junction obstruction. Pediatr Surg Int. 2009;25(1):61–7.PubMedCrossRef
28.
go back to reference Gordon I. Diuretic renography in infants with prenatal unilateral hydronephrosis: an explanation for the controversy about poor drainage. BJU Int. 2001;87:551–5.PubMedCrossRef Gordon I. Diuretic renography in infants with prenatal unilateral hydronephrosis: an explanation for the controversy about poor drainage. BJU Int. 2001;87:551–5.PubMedCrossRef
29.
go back to reference Eskild-Jensen A, Gordon I, Piepsz A, Frokiaer J. Interpretation of the renogram: problems and pitfalls in hydronephrosis in children. BJU Int. 2004;94(6):887–92.PubMedCrossRef Eskild-Jensen A, Gordon I, Piepsz A, Frokiaer J. Interpretation of the renogram: problems and pitfalls in hydronephrosis in children. BJU Int. 2004;94(6):887–92.PubMedCrossRef
30.
go back to reference Koff SA. Postnatal management of antenatal hydronephrosis using an observational approach. Urology. 2000;55(5):609–11.PubMedCrossRef Koff SA. Postnatal management of antenatal hydronephrosis using an observational approach. Urology. 2000;55(5):609–11.PubMedCrossRef
31.
go back to reference Dhillon H. Prenatally diagnosed hydronephrosis: the Great Ormond Street experience. Br J Urol. 1998;81:39–44.PubMedCrossRef Dhillon H. Prenatally diagnosed hydronephrosis: the Great Ormond Street experience. Br J Urol. 1998;81:39–44.PubMedCrossRef
32.•
go back to reference Ulman I, Jayanthi V, Koff S. The long-term followup of newborns with severe unilateral hydronephrosis initially treated nonoperatively. J Urol. 2000;164:1101. This prospective cohort study better defined the association between initial imaging and risk of renal deterioration in infants with severe hydronephrosis. PubMedCrossRef Ulman I, Jayanthi V, Koff S. The long-term followup of newborns with severe unilateral hydronephrosis initially treated nonoperatively. J Urol. 2000;164:1101. This prospective cohort study better defined the association between initial imaging and risk of renal deterioration in infants with severe hydronephrosis. PubMedCrossRef
33.
go back to reference Castagnetti M, Novara G, Beniamin F, Vezzu B, Rigamonti W, Artibani W. Scintigraphic renal function after unilateral pyeloplasty in children: a systematic review. BJU Int. 2008;102(7):862–8.PubMedCrossRef Castagnetti M, Novara G, Beniamin F, Vezzu B, Rigamonti W, Artibani W. Scintigraphic renal function after unilateral pyeloplasty in children: a systematic review. BJU Int. 2008;102(7):862–8.PubMedCrossRef
34.
go back to reference McAleer IM, Kaplan GW. Renal function before and after pyeloplasty: does it improve? J Urol. 1999;162(3 pt 2):1041–4.PubMed McAleer IM, Kaplan GW. Renal function before and after pyeloplasty: does it improve? J Urol. 1999;162(3 pt 2):1041–4.PubMed
35.
go back to reference Eskild-Jensen A, Munch Jorgensen T, Olsen LH, Djurhuus JC, Frokiaer J. Renal function may not be restored when using decreasing differential function as the criterion for surgery in unilateral hydronephrosis. BJU Int. 2003;92(7):779–82.PubMedCrossRef Eskild-Jensen A, Munch Jorgensen T, Olsen LH, Djurhuus JC, Frokiaer J. Renal function may not be restored when using decreasing differential function as the criterion for surgery in unilateral hydronephrosis. BJU Int. 2003;92(7):779–82.PubMedCrossRef
36.
go back to reference Sharma G, Sharma A, Maheshwari P. Predictive value of decreased renal pelvis anteroposterior diameter in prone position for prenatally detected hydronephrosis. J Urol. 2012;187(5):1839–43.PubMedCrossRef Sharma G, Sharma A, Maheshwari P. Predictive value of decreased renal pelvis anteroposterior diameter in prone position for prenatally detected hydronephrosis. J Urol. 2012;187(5):1839–43.PubMedCrossRef
37.
go back to reference Thorup J, Jokela R, Cortes D, Nielsen OH. The results of 15 years of consistent strategy in treating antenatally suspected pelvi-ureteric junction obstruction. BJU Int. 2003;91(9):850–2.PubMedCrossRef Thorup J, Jokela R, Cortes D, Nielsen OH. The results of 15 years of consistent strategy in treating antenatally suspected pelvi-ureteric junction obstruction. BJU Int. 2003;91(9):850–2.PubMedCrossRef
38.
go back to reference Vasconcelos MA, Bouzada MC, Silveira KD, Moura LR, Santos FF, Oliveira JM, et al. Urinary levels of TGF β-1 and of cytokines in patients with prenatally detected nephrouropathies. Pediatr Nephrol. 2011;26(5):739–47.PubMedCrossRef Vasconcelos MA, Bouzada MC, Silveira KD, Moura LR, Santos FF, Oliveira JM, et al. Urinary levels of TGF β-1 and of cytokines in patients with prenatally detected nephrouropathies. Pediatr Nephrol. 2011;26(5):739–47.PubMedCrossRef
39.
go back to reference Madsen MG, Norregaard R, Frokiaer J, Jorgensen TM. Urinary biomarkers in prenatally diagnosed unilateral hydronephrosis. J Pediatr Urol. 2011;7:105–12.PubMedCrossRef Madsen MG, Norregaard R, Frokiaer J, Jorgensen TM. Urinary biomarkers in prenatally diagnosed unilateral hydronephrosis. J Pediatr Urol. 2011;7:105–12.PubMedCrossRef
40.
go back to reference Furness III PD, Maizels M, Han SW, Cohn RA, Cheng EY. Elevated bladder urine concentration of transforming growth factor-beta1 correlates with upper urinary tract obstruction in children. J Urol. 1999;162(3 pt 2):1033–6.PubMedCrossRef Furness III PD, Maizels M, Han SW, Cohn RA, Cheng EY. Elevated bladder urine concentration of transforming growth factor-beta1 correlates with upper urinary tract obstruction in children. J Urol. 1999;162(3 pt 2):1033–6.PubMedCrossRef
41.
go back to reference Madsen MG, Norregaard R, Palmfeldt J, Olsen LH, Frokiaer J, Jorgensen TM. Epidermal growth factor and monocyte chemotactic peptide-1: potential biomarkers of urinary tract obstruction in children with hydronephrosis. J Pediatr Urol. 2013;9(6 pt A):838–45.PubMedCrossRef Madsen MG, Norregaard R, Palmfeldt J, Olsen LH, Frokiaer J, Jorgensen TM. Epidermal growth factor and monocyte chemotactic peptide-1: potential biomarkers of urinary tract obstruction in children with hydronephrosis. J Pediatr Urol. 2013;9(6 pt A):838–45.PubMedCrossRef
42.
go back to reference Taranta-Janusz K, Wasilewska A, Debek W, Waszkeiwicz-Stojda M. Urinary cytokine profiles in unilateral congenital hydronephrosis. Pediatr Nephrol. 2012;27:2107–13.PubMedCentralPubMedCrossRef Taranta-Janusz K, Wasilewska A, Debek W, Waszkeiwicz-Stojda M. Urinary cytokine profiles in unilateral congenital hydronephrosis. Pediatr Nephrol. 2012;27:2107–13.PubMedCentralPubMedCrossRef
43.
go back to reference Madsen MG, Norregaard R, Palmfeldt J, Olsen LH, Frokiaer J, Jorgensen TM. Urinary NGAL, cystatin C, β2-microglobulin, and osteopontin significance in hydronephrotic children. Pediatr Nephrol. 2012;27(11):2099–106.PubMedCrossRef Madsen MG, Norregaard R, Palmfeldt J, Olsen LH, Frokiaer J, Jorgensen TM. Urinary NGAL, cystatin C, β2-microglobulin, and osteopontin significance in hydronephrotic children. Pediatr Nephrol. 2012;27(11):2099–106.PubMedCrossRef
44.
go back to reference Cost NG, Noh PH, Devarajan P, Ivancic V, Reddy PP, Minevich E, et al. Urinary NGAL levels correlate with differential renal function in patients with ureteropelvic junction obstruction undergoing pyeloplasty. J Urol. 2013;190(4 Suppl):1462–7.PubMedCrossRef Cost NG, Noh PH, Devarajan P, Ivancic V, Reddy PP, Minevich E, et al. Urinary NGAL levels correlate with differential renal function in patients with ureteropelvic junction obstruction undergoing pyeloplasty. J Urol. 2013;190(4 Suppl):1462–7.PubMedCrossRef
45.
go back to reference Passerotti CC, Kalish LA, Chow J, Passerotti AM, Recabal P, Cendron M, et al. The predictive value of the first postnatal ultrasound in children with antenatal hydronephrosis. J Pediatr Urol. 2011;7(2):128–36.PubMedCrossRef Passerotti CC, Kalish LA, Chow J, Passerotti AM, Recabal P, Cendron M, et al. The predictive value of the first postnatal ultrasound in children with antenatal hydronephrosis. J Pediatr Urol. 2011;7(2):128–36.PubMedCrossRef
46.
go back to reference Barbosa JA, Chow JS, Benson CB, Yorioka MA, Bull AS, Retik AB, et al. Postnatal longitudinal evaluation of children diagnosed with prenatal hydronephrosis: insights in natural history and referral pattern. Prenat Diagn. 2012;32(13):1242–9.PubMedCrossRef Barbosa JA, Chow JS, Benson CB, Yorioka MA, Bull AS, Retik AB, et al. Postnatal longitudinal evaluation of children diagnosed with prenatal hydronephrosis: insights in natural history and referral pattern. Prenat Diagn. 2012;32(13):1242–9.PubMedCrossRef
47.
go back to reference Matsui F, Shimada K, Matsumoto F, Takano S. Late recurrence of symptomatic hydronephrosis in patients with prenatally detected hydronephrosis and spontaneous improvement. J Urol. 2008;180:322.PubMedCrossRef Matsui F, Shimada K, Matsumoto F, Takano S. Late recurrence of symptomatic hydronephrosis in patients with prenatally detected hydronephrosis and spontaneous improvement. J Urol. 2008;180:322.PubMedCrossRef
48.
go back to reference Koff SA, Campbell K. Nonoperative management of unilateral neonatal hydronephrosis. J Urol. 1992;148:525.PubMed Koff SA, Campbell K. Nonoperative management of unilateral neonatal hydronephrosis. J Urol. 1992;148:525.PubMed
49.
go back to reference Chertin B, Pollack A, Koulikov D, Rabinowitz R, Hain D, Hadas-Halpren I, et al. Conservative treatment of ureteropelvic junction obstruction in children with antenatal diagnosis of hydronephrosis: lessons learned after 16 years of follow-up. Eur Urol. 2006;49(4):734–8.PubMedCrossRef Chertin B, Pollack A, Koulikov D, Rabinowitz R, Hain D, Hadas-Halpren I, et al. Conservative treatment of ureteropelvic junction obstruction in children with antenatal diagnosis of hydronephrosis: lessons learned after 16 years of follow-up. Eur Urol. 2006;49(4):734–8.PubMedCrossRef
50.
go back to reference Koff S, Campbell K. The nonoperative management of unilateral neonatal hydronephrosis: natural history of poorly functioning kidneys. J Urol. 1994;152:593–5.PubMed Koff S, Campbell K. The nonoperative management of unilateral neonatal hydronephrosis: natural history of poorly functioning kidneys. J Urol. 1994;152:593–5.PubMed
51.
go back to reference Molina CA, Facincani I, Muglia VF, Araujo WM, Cassini MF, Tucci Jr S. Postnatal evaluation of intrauterine hydronephrosis due to ureteropelvic junction obstruction. Acta Cir Bras. 2013;28 Suppl 1:33–6.PubMedCrossRef Molina CA, Facincani I, Muglia VF, Araujo WM, Cassini MF, Tucci Jr S. Postnatal evaluation of intrauterine hydronephrosis due to ureteropelvic junction obstruction. Acta Cir Bras. 2013;28 Suppl 1:33–6.PubMedCrossRef
52.
go back to reference Bajpai M, Chandrasekharam VV. Nonoperative management of neonatal moderate to severe bilateral hydronephrosis. J Urol. 2002;167(2 pt 1):662–5.PubMedCrossRef Bajpai M, Chandrasekharam VV. Nonoperative management of neonatal moderate to severe bilateral hydronephrosis. J Urol. 2002;167(2 pt 1):662–5.PubMedCrossRef
53.
go back to reference Hubertus J, Plieninger S, Martinovic V, Heinrich M, Schuster T, Burst M, et al. Children and adolescents with ureteropelvic junction obstruction: is an additional voiding cystoureterogram necessary/ Results of a multicenter study. World J Urol. 2013;3193:683–7.CrossRef Hubertus J, Plieninger S, Martinovic V, Heinrich M, Schuster T, Burst M, et al. Children and adolescents with ureteropelvic junction obstruction: is an additional voiding cystoureterogram necessary/ Results of a multicenter study. World J Urol. 2013;3193:683–7.CrossRef
54.••
go back to reference Wheeler DM, Vimalachandra D, Hodson EM, Roy LP, Smith GH, Craig JC. Interventions for primary vesicoureteral reflux. Cochrane Database Syst Rev 2004. This meta-analysis questioned the role of antibiotic prophylaxis and surgery in preventing renal scarring in children with vesicoureteral reflux and established the number needed to treat to prevent one febrile UTI in this population. Wheeler DM, Vimalachandra D, Hodson EM, Roy LP, Smith GH, Craig JC. Interventions for primary vesicoureteral reflux. Cochrane Database Syst Rev 2004. This meta-analysis questioned the role of antibiotic prophylaxis and surgery in preventing renal scarring in children with vesicoureteral reflux and established the number needed to treat to prevent one febrile UTI in this population.
55.
go back to reference de Bruyn R, Marks SD. Postnatal investigation of fetal renal disease. Semin Fetal Neonatal Med. 2008;13:133–41.PubMedCrossRef de Bruyn R, Marks SD. Postnatal investigation of fetal renal disease. Semin Fetal Neonatal Med. 2008;13:133–41.PubMedCrossRef
56.
go back to reference Onen A, Jayanthi VR, Koff SA. Long-term follow up of prenatally detected severe bilateral newborn hydronephrosis initially managed nonoperatively. J Urol. 2002;168(3):1118–20.PubMedCrossRef Onen A, Jayanthi VR, Koff SA. Long-term follow up of prenatally detected severe bilateral newborn hydronephrosis initially managed nonoperatively. J Urol. 2002;168(3):1118–20.PubMedCrossRef
57.
go back to reference Braga LH, Mijovic H, Farrokhyar F, Pemberton J, Demaria J, Lorenzo AJ. Antibiotic prophylaxis for urinary tract infections in antenatal hydronephrosis. Pediatrics. 2013;131(1):251–61.CrossRef Braga LH, Mijovic H, Farrokhyar F, Pemberton J, Demaria J, Lorenzo AJ. Antibiotic prophylaxis for urinary tract infections in antenatal hydronephrosis. Pediatrics. 2013;131(1):251–61.CrossRef
58.
go back to reference Alconcher L, Tombesi M. Mild antenatal hydronephrosis: management controversies. Pediatr Nephrol. 2004;19:819.PubMedCrossRef Alconcher L, Tombesi M. Mild antenatal hydronephrosis: management controversies. Pediatr Nephrol. 2004;19:819.PubMedCrossRef
59.
go back to reference Roth CC, Hubanks JM, Bright BC, Heinlen JE, Donovan BO, Kropp BP, et al. Occurrence of urinary tract infection in children with significant upper tract obstruction. Urology. 2009;73(1):74–8.PubMedCrossRef Roth CC, Hubanks JM, Bright BC, Heinlen JE, Donovan BO, Kropp BP, et al. Occurrence of urinary tract infection in children with significant upper tract obstruction. Urology. 2009;73(1):74–8.PubMedCrossRef
Metadata
Title
Prenatal Hydronephrosis: Postnatal Evaluation and Management
Authors
Vijaya Vemulakonda
Jenny Yiee
Duncan T. Wilcox
Publication date
01-08-2014
Publisher
Springer US
Published in
Current Urology Reports / Issue 8/2014
Print ISSN: 1527-2737
Electronic ISSN: 1534-6285
DOI
https://doi.org/10.1007/s11934-014-0430-5

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