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01-12-2018 | Invited Commentary

Medication Decision-making in Osteoporosis: Can We Explain Why Patients Do Not Take Their Osteoporosis Medications?

Authors: Stuart Silverman, Deborah T. Gold

Published in: Current Osteoporosis Reports | Issue 6/2018

Abstract

Patients at high risk of fracture often do not take medication for osteoporosis. Recent literature may give us some insights into why patients at high risk of fracture do not take medications for osteoporosis.

Guggina P, Flahive J, Hooven FH, et al. Characteristics associated with anti-osteoporosis medication use data from the Global Longitudinal Study of Osteoporosis in Women (GLOW) USA cohort. Bone. 2012;51:975–80.CrossRef

Reynolds K, Muntner P, Cheetham TC, Harrison TN, Morisky DE, Silverman S, et al. Primary nonadherence to bisphosphonates in an integrated healthcare setting. Osteoporos Int. 2013;24:2509–17.CrossRef

Gold DT, Silverman S. Review of adherence to medications for the treatment of osteoporosis. Curr Osteop Rep. 2006;4:21–7.CrossRef

Silverman S, Gold DT. Compliance and persistence with osteoporosis medications: a critical review of the literature. Rev Endocr Metab Disord. 2010;11:275–80.CrossRef

Fischoff B, Slovic P, Lichtenstein S, et al. How safe is safe enough? A psychometric study of attitudes towards technological risks and benefits. Policy Sci. 1978;9:127–52.CrossRef

Weiss TW, Gold DT, Silverman SL, McHorney CA. An evaluation of patient preferences for osteoporosis medication attributes: results from the PREFER-US study. Curr Med Res Opin. 2006;22:949–60.CrossRef

Silverman S, Calderon A, Kaw K, Childers TB, Stafford BA, Brynildsen W, et al. Patient weighting of osteoporosis medication attributes across racial and ethnic groups: a study of osteoporosis medication preferences using conjoint analysis. Osteoporos Int. 2013;24:2067–77.CrossRef

Lloyd AJ. The extent of patients’ understanding of the risk of treatments. Quality Health Care. 2001;10(suppl 1):i4–i18.

Weinstein ND. Optimistic biases about personal risks. Science. 1989;246:1232–3.CrossRef

10.

Siris ES, Gehlbach S, Adachi JD, Boonen S, Chapurlat RD, Compston JE, et al. Failure to perceive increased risk of fracture in women 55 years and older: the Global Longitudinal Study of Osteoporosis in Women (GLOW). Osteoporos Int. 2011;22:27–35.CrossRef

11.

Redelmeier DA, Rozin P, Kahneman D. Understanding patients’ decisions: cognitive and emotional perspectives. JAMA. 1993;27:72–6.CrossRef

12.

Paling J. Strategies to help patients understand risk. BMJ. 2003;327:745–8.CrossRef

13.

Bennett. Understanding response to risk: some basic findings. In: Bennett P, Calman K, editors. Risk communication and public health. Oxford: Oxford Medical Publications; 1999. p. 3–19.

14.

Silverman S, Qu H, Curtis J, et. al. Understanding physicians’ perceptions of patients’ barriers to osteoporosis medication initiation. Presented at ASBMR; 2014. Available at http://www.asbmr.org/education/AbstractDetail?aid=8f4fc96a-8ef1-4f7b-8dda-fa7d2737da1c Accessed 28 Feb 2015.

15.

Kessels RC. Patients’ memory for medical information. J R Soc Med. 2003;96(5):219–22.PubMedPubMedCentral

16.

Anderson JL, Dodman S, Kopelman M, Fleming A. Patient information recall in a rheumatology clinic. Rheumatol Rehabil. 1979;18:245–55.CrossRef

17.

Campos B, Schetter CD, Abdou CM, Hobel CJ, Glynn LM, Sandman CA. Familialism, social support and stress: positive implications for pregnant Latinas. Cult Divers Ethn Minor Psychol. 2008;14:155–62.CrossRef

18.

Silverman SL, Greenwald M, Klein RA, et al. Effect of bone density information on decisions about hormone replacement therapy: a randomized trial. Obstet Gynecol. 1997;89:321–5.CrossRef

19.

Wang C, O’Neill RN, et al. Comparison of risk perceptions and beliefs across common chronic diseases. Prev Med. 2009;48:197–202.CrossRef

20.

Solimeo SL, Weber TJ, Gold DT. Older men’s explanatory model for osteoporosis. The Gerontologist. 2011;51(4):530–9.CrossRef

21.

Hutchins R, Viera AJ, Sheridan SL, Pignone MP. Quantifying the utility of taking pills for cardiovascular prevention. Circ Cardiovasc Qual Outcomes. 2015;8:155–63.CrossRef

22.

Curtis JR, Xi J, Westfall AO, Cheng H, Lyles K, Saag KG, et al. Improving the prediction of medication compliance: the example of bisphosphonates for osteoporosis. Med Care. 2009;47(3):334–41.CrossRef

23.

Reyna VF, al NWLE. How numeracy influences risk comprehension and medical decision making. Psychol Bull. 2009;135:943–73.CrossRef

24.

Grimes DA, Snively GR. Patients understanding of medical risks: implications for genetic counseling. Obstet Gynecol. 1999;93:910–4.PubMed

25.

Leblanc A, Wang AT, Wyatt K, et al. Encounter decision aid vs. clinical decision support or usual care to support patient-centered treatment decisions in osteoporosis: the osteoporosis choice randomized trial II. PLoS One. 2015;10(5):e0128063. https://doi.org/10.1371/journal.pone.0128063. eCollection 2015.CrossRefPubMedPubMedCentral

Title: Medication Decision-making in Osteoporosis: Can We Explain Why Patients Do Not Take Their Osteoporosis Medications?
Authors: Stuart Silverman
Deborah T. Gold
Publication date: 01-12-2018
Publisher: Springer US
Published in: Current Osteoporosis Reports / Issue 6/2018
Print ISSN: 1544-1873
Electronic ISSN: 1544-2241
DOI: https://doi.org/10.1007/s11914-018-0494-0

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Medication Decision-making in Osteoporosis: Can We Explain Why Patients Do Not Take Their Osteoporosis Medications?

Abstract

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

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