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Current Infectious Disease Reports

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13-06-2022 | Chlamydia Trachomatis | HIV/AIDS (C Yoon, Section Editor)

What’s Old Is New: the Evolution of Lymphogranuloma Venereum Proctitis in Persons Living with HIV

Authors: Ronnie M. Gravett, Jeanne Marrazzo

Published in: Current Infectious Disease Reports | Issue 8/2022

Abstract

Purpose of Review

Lymphogranuloma venereum (LGV) has re-emerged as a consequential anorectal sexually transmitted infection with high burden among persons living with HIV, especially men who have sex with men (MSM).

Recent Findings

Surveillance programs are limited without widely available LGV-specific diagnostics, but LGV prevalence is becoming increasingly recognized as it spreads globally. The LGV epidemic remains high among MSM living with HIV and is now shifting to include more HIV-negative MSM. LGV testing of asymptomatic persons at high risk will increase case finding and potential for earlier intervention. Doxycycline remains the guideline-directed treatment of choice, but recent data may support shorter duration or even use of azithromycin as alternatives.

Summary

While the burden of LGV is appreciated as a significant cause of proctitis, especially among MSM living with HIV, lack of accessible diagnostics limits our understanding of actual incidence and its impact on the HIV epidemic. Future directions should include assay validation for widespread use and rigorous clinical trials to examine treatment durations based on symptom burden.

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Title: What’s Old Is New: the Evolution of Lymphogranuloma Venereum Proctitis in Persons Living with HIV
Authors: Ronnie M. Gravett
Jeanne Marrazzo
Publication date: 13-06-2022
Publisher: Springer US
Keywords: Chlamydia Trachomatis
Doxycycline
Sexually Transmitted Infection
Sexually Transmitted Infection
Proctitis
Sexually Transmitted Infection
Human Immunodeficiency Virus
Chlamydia Trachomatis
Sexually Transmitted Infection
Published in: Current Infectious Disease Reports / Issue 8/2022
Print ISSN: 1523-3847
Electronic ISSN: 1534-3146
DOI: https://doi.org/10.1007/s11908-022-00781-6

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What’s Old Is New: the Evolution of Lymphogranuloma Venereum Proctitis in Persons Living with HIV

Abstract

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Abstract

Purpose of Review

Recent Findings

Summary

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ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

» View more highlights on the ACC 2024 congress hub page