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Current Hypertension Reports
Published in: Current Hypertension Reports 10/2019

01-10-2019 | Hypertension | NUTRITION AND HYPERTENSION (T MORI, SECTION EDITOR)

Alcohol and Hypertension—New Insights and Lingering Controversies

Authors: Ian B. Puddey, Trevor A. Mori, Anne E. Barden, Lawrence J. Beilin

Published in: Current Hypertension Reports | Issue 10/2019

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Abstract

Purpose of Review

To examine outstanding issues in the relationship of alcohol to hypertension. These include whether the increase in BP with alcohol is causally related, the nature of the relationship in women, the contribution of alcohol-related increases in BP to cardiovascular disease and the aetiology of alcohol-related hypertension.

Recent Findings

Intervention studies and Mendelian randomisation analyses confirm the alcohol–BP relationship is causal. The concept that low-level alcohol intake reduces BP in women is increasingly unsustainable. Alcohol-related hypertension is in the causal pathway between alcohol use and increased risk for several cardiovascular outcomes. The aetiology of alcohol-related hypertension is multifactorial with recent data highlighting the effects of alcohol on the vasoconstrictor 20-HETE and oxidative stress.

Summary

The high prevalence of both alcohol use and hypertension mandates a careful alcohol history in every patient with elevated BP. Early intervention for excessive alcohol use offers the promise of lower levels of BP and reduced risk of adverse cardiovascular outcomes.
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Metadata
Title
Alcohol and Hypertension—New Insights and Lingering Controversies
Authors
Ian B. Puddey
Trevor A. Mori
Anne E. Barden
Lawrence J. Beilin
Publication date
01-10-2019
Publisher
Springer US
Published in
Current Hypertension Reports / Issue 10/2019
Print ISSN: 1522-6417
Electronic ISSN: 1534-3111
DOI
https://doi.org/10.1007/s11906-019-0984-1

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WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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