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Current HIV/AIDS Reports
Published in: Current HIV/AIDS Reports 6/2019

01-12-2019 | Care | The Global Epidemic (SH Vermund, Section Editor)

Interventions to improve the HIV continuum of care in China

Authors: Xiangjun Zhang, Na Wang, Sten H. Vermund, Huachun Zou, Xianhong Li, Fujie Zhang, Han-Zhu Qian

Published in: Current HIV/AIDS Reports | Issue 6/2019

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Abstract

Purpose of Review

To describe HIV epidemic and interventions for improving HIV continuum of care in China.

Recent Findings

The reported HIV epidemic has been continuously increasing, partially due to the expansion of active HIV testing campaign. Public health intervention programs have been effective in containing HIV spread among former plasma donors and people who inject drugs (PWID), but more infections occur among heterosexual men and women and young men who have sex with men. Of 1.25 million Chinese people are living with HIV, one-third do not know their status. About two-thirds of diagnosed individuals have used antiretroviral therapy (ART) and two-thirds of those on ART have achieved viral suppression, but some risk groups such as PWID have lower rates. The national free ART program has reduced adult and pediatric mortality and reduced heterosexual transmission.

Summary

China faces great challenges to reduce HIV sexual transmission, improve the HIV continuum of care, and close the gaps to the UNAIDS Three “90” Targets.
Literature
1.
Yu ES, Xie Q, Zhang K, Lu P, Chan LL. HIV infection and AIDS in China, 1985 through 1994. Am J Public Health. 1996;86(8):1116–22.PubMedPubMedCentral
2.
Wang L. Overview of the HIV/AIDS epidemic, scientific research and government responses in China. AIDS. 2007;21(Suppl 8):S3–7.PubMed
3.
Chen H, Luo L, Pan SW, et al. HIV epidemiology and prevention in southwestern China: trends from 1996-2017. Curr HIV Res. 2019.
4.
Qian ZH, Vermund SH, Wang N. Risk of HIV/AIDS in China: subpopulations of special importance. Sexually transmitted infections. 2005;81(6):442–7.PubMedPubMedCentral
5.
Qian H-Z, Schumacher JE, Chen HT, Ruan Y-H. Injection drug use and HIV/AIDS in China: review of current situation, prevention and policy implications. Harm reduction journal. 2006;3(1):4.PubMedPubMedCentral
6.
Qian HZ, Vermund SH, Kaslow RA, et al. Co-infection with HIV and hepatitis C virus in former plasma/blood donors: challenge for patient care in rural China. AIDS. 2006;20(10):1429–35.PubMed
7.
Qian HZ, Yang Z, Shi X, Gao J, Xu C, Wang L, et al. Hepatitis C virus infection in former commercial plasma/blood donors in rural Shanxi Province, China: the China Integrated Programs for Research on AIDS. J Infect Dis. 2005;192(10):1694–700.PubMed
8.
Wang N, Wang L, Wu Z, et al. Estimating the number of people living with HIV/AIDS in China: 2003–09. International journal of epidemiology. 2010;39(suppl_2):ii21–8.PubMedPubMedCentral
9.
10.
Zheng X, Zhang JP, Qu SQ. A cohort study of HIV infection among intravenous drug users in Ruili and other two counties in Yunnan Province, China, 1992-1995. Zhonghua liu xing bing xue za zhi=. Zhonghua liuxingbingxue zazhi. 1997;18(5):259–62.PubMed
11.
12.
Gao L, Zhang L, Jin Q. Meta-analysis: prevalence of HIV infection and syphilis among MSM in China. Sexually transmitted infections. 2009;85(5):354–8.PubMed
13.
Zhang X, Yu J, Li M, Sun X, Han Q, Li M, et al. Prevalence and related risk behaviors of HIV, syphilis, and anal HPV infection among men who have sex with men from Beijing. China. AIDS and Behavior. 2013;17(3):1129–36.PubMed
14.
Standing Committee of the National People’s Congress. Law on the control of the entry and exit of aliens. Order number 31 of the President of the People’s Republic of China. Beijing, 1985 (in Chinese).
15.
Ministry of Health of the People’s Republic of China. Notice on banning import of blood products such as factor VIII. State Council Document (1985) number 49. Beijing, 1986 (in Chinese).
16.
Zhao B, Li X. Studies in drug-related crime. Beijing: Chinese People's University Press; 1993.
17.
Standing Committee of the National People’s Congress. Frontier health and quarantine law. Order number 46 of the President of the People’s Republic of China. Beijing, 1987 (in Chinese).
18.
Wu Z, Sullivan SG, Wang Y, Rotheram-Borus MJ, Detels R. Evolution of China's response to HIV/AIDS. The Lancet. 2007;369(9562):679–90.
19.
Li D, Xia G, Qiu R, Hamblin J, Yue T. Law, policies and regulations concerning HIV/AIDS prevention and containment: an assessment and recommendations. United Nations Development Programme: Beijing; 2003.
20.
Dou Z, Chen RY, Wang Z, Ji G, Peng G, Qiao X, et al. HIV-infected former plasma donors in rural Central China: from infection to survival outcomes, 1985-2008. PLoS One. 2010;5(10):e13737.PubMedPubMedCentral
21.
Chen S, Zhao H, Zhao C, et al. Eighteen-year follow-up report of the surveillance and prevention of an HIV/AIDS outbreak amongst plasma donors in Hebei Province, China. BMC Infect Dis. 2015;15:316.PubMedPubMedCentral
22.
Lu W, Zeng G, Luo J, Duo S, Xing G, Guo-Wei D, et al. HIV transmission risk among serodiscordant couples: a retrospective study of former plasma donors in Henan, China. J Acquir Immune Defic Syndr. 2010;55(2):232–8.PubMedPubMedCentral
23.
Tang H, Wu Z, Mao Y, Cepeda J, Morano J. Risk factor associated with negative spouse HIV seroconversion among sero-different couples: a nested case-control retrospective survey study in 30 counties in rural China. PLoS One. 2016;11(10):e0164761.PubMedPubMedCentral
24.
Luo W, Wu Z, Poundstone K, et al. Needle and syringe exchange programmes and prevalence of HIV infection among intravenous drug users in China. Addiction. 2015;110(Suppl 1):61–7.PubMed
25.
Zou X, Ling L, Zhang L. Trends and risk factors for HIV, HCV and syphilis seroconversion among drug users in a methadone maintenance treatment programme in China: a 7-year retrospective cohort study. BMJ Open. 2015;5(8):e008162.PubMedPubMedCentral
26.
Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365(6):493–505.PubMedPubMedCentral
27.
Rodger AJ, Cambiano V, Bruun T, Vernazza P, Collins S, van Lunzen J, et al. Sexual activity without condoms and risk of HIV transmission in serodifferent couples when the HIV-positive partner is using suppressive antiretroviral therapy. JAMA. 2016;316(2):171–81.PubMed
28.
Bavinton BR, Pinto AN, Phanuphak N, Grinsztejn B, Prestage GP, Zablotska-Manos IB, et al. Viral suppression and HIV transmission in serodiscordant male couples: an international, prospective, observational, cohort study. Lancet HIV. 2018;5(8):e438–47.PubMed
29.
Panlilio AL, Cardo DM, Grohskopf LA, Heneine W, Ross CS, Service USPH. Updated U.S. Public Health Service guidelines for the management of occupational exposures to HIV and recommendations for postexposure prophylaxis. MMWR Recomm Rep. 2005;54(RR-9):1–17.PubMed
30.
Grant RM, Lama JR, Anderson PL, McMahan V, Liu AY, Vargas L, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010;363(27):2587–99.PubMedPubMedCentral
31.
Choopanya K, Martin M, Suntharasamai P, et al. Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok Tenofovir Study): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet. 2013;381(9883):2083–90.PubMed
32.
Gray RH, Kigozi G, Serwadda D, Makumbi F, Watya S, Nalugoda F, et al. Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial. Lancet. 2007;369(9562):657–66.PubMed
33.
Auvert B, Taljaard D, Lagarde E, Sobngwi-Tambekou J, Sitta R, Puren A. Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 Trial. PLoS Med. 2005;2(11):e298.PubMedPubMedCentral
34.
Bailey RC, Moses S, Parker CB, Agot K, Maclean I, Krieger JN, et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. Lancet. 2007;369(9562):643–56.PubMed
35.
Ruan Y, Qian HZ, Li D, Shi W, Li Q, Liang H, et al. Willingness to be circumcised for preventing HIV among Chinese men who have sex with men. AIDS Patient Care STDS. 2009;23(5):315–21.PubMedPubMedCentral
36.
Zhang C, Penson DF, Qian HZ, Webb GF, Lou J, Shephard BE, et al. Modeling economic and epidemiological impact of voluntary medical male circumcision among men who have sex with men in Beijing, China. Int J STD AIDS. 2019;30(7):630–8.PubMedPubMedCentral
37.
Qian HZ, Ruan Y, Liu Y, Milam DF, Spiegel HM, Yin L, et al. Lower HIV risk among circumcised men who have sex with men in China: interaction with anal sex role in a cross-sectional study. J Acquir Immune Defic Syndr. 2016;71(4):444–51.PubMedPubMedCentral
38.
Yuan T, Fitzpatrick T, Ko NY, Cai Y, Chen Y, Zhao J, et al. Circumcision to prevent HIV and other sexually transmitted infections in men who have sex with men: a systematic review and meta-analysis of global data. Lancet Glob Health. 2019;7(4):e436–47.PubMedPubMedCentral
39.
Yuan T, Qian HZ, Wang J, Gao Y, Zou H. Is circumcision an answer for HIV prevention in men who have sex with men? - authors’ reply. Lancet Glob Health. 2019;7(8):e1012.PubMed
40.
Lou J, Blevins M, Ruan Y, Vermund SH, Tang S, Webb GF, et al. Modeling the impact on HIV incidence of combination prevention strategies among men who have sex with men in Beijing. China. PLoS One. 2014;9(3):e90985.PubMed
41.
McNairy ML, Lamb MR, Gachuhi AB, Nuwagaba-Biribonwoha H, Burke S, Mazibuko S, et al. Effectiveness of a combination strategy for linkage and retention in adult HIV care in Swaziland: the Link4Health cluster randomized trial. PLoS Med. 2017;14(11):e1002420.PubMedPubMedCentral
42.
Elul B, Lamb MR, Lahuerta M, Abacassamo F, Ahoua L, Kujawski SA, et al. A combination intervention strategy to improve linkage to and retention in HIV care following diagnosis in Mozambique: a cluster-randomized study. PLoS Med. 2017;14(11):e1002433.PubMedPubMedCentral
43.
Lou J, Hu P, Qian HZ, Ruan Y, Jin Z, Xing H, et al. Expanded antiretroviral treatment, sexual networks, and condom use: treatment as prevention unlikely to succeed without partner reduction among men who have sex with men in China. PLoS One. 2017;12(4):e0171295.PubMedPubMedCentral
44.
Zhang L, Chow EP, Su S, Yiu WL, Zhang X, Iu KI, et al. A systematic review and meta-analysis of the prevalence, trends, and geographical distribution of HIV among Chinese female sex workers (2000-2011): implications for preventing sexually transmitted HIV. Int J Infect Dis. 2015;39:76–86.PubMed
45.
46.
Li YZ, Xu JJ, Qian HZ, et al. High prevalence of HIV infection and unprotected anal intercourse among older men who have sex with men in China: a systematic review and meta-analysis. BMC Infect Dis. 2014;14:531.PubMedPubMedCentral
47.
Li Y, Xu J, Reilly KH, Zhang J, Wei H, Jiang Y, et al. Prevalence of HIV and syphilis infection among high school and college student MSM in China: a systematic review and meta-analysis. PLoS One. 2013;8(7):e69137.PubMedPubMedCentral
48.
Zhang L, Ding X, Lu R, Feng L, Li X, Xiao Y, et al. Predictors of HIV and syphilis among men who have sex with men in a Chinese metropolitan city: comparison of risks among students and non-students. PLoS One. 2012;7(5):e37211.PubMedPubMedCentral
49.
Chen Y, Abraham Bussell S, Shen Z, Tang Z, Lan G, Zhu Q, et al. Declining inconsistent condom use but increasing HIV and syphilis prevalence among older male clients of female sex workers: analysis from sentinel surveillance sites (2010-2015), Guangxi, China. Medicine (Baltimore). 2016;95(22):e3726.PubMedPubMedCentral
50.
Zhang J, Xu JJ, Song W, Pan S, Chu ZX, Hu QH, et al. HIV incidence and care linkage among MSM first-time-testers in Shenyang, China 2012-2014. AIDS Behav. 2018;22(3):711–21.PubMed
51.
Chen Q, Sun Y, Sun W, Hao M, Li G, Su X, et al. Trends of HIV incidence and prevalence among men who have sex with men in Beijing, China: nine consecutive cross-sectional surveys, 2008-2016. PLoS One. 2018;13(8):e0201953.PubMedPubMedCentral
52.
Hong Y, Zhang C, Li X, Fang X, Lin X, Zhou Y, et al. HIV testing behaviors among female sex workers in Southwest China. AIDS Behav. 2012;16(1):44–52.PubMedPubMedCentral
53.
Chow EP, Muessig KE, Yuan L, Wang Y, Zhang X, Zhao R, et al. Risk behaviours among female sex workers in China: a systematic review and data synthesis. PLoS One. 2015;10(3):e0120595.PubMedPubMedCentral
54.
Fang Y, Zhang Y, Wang Z, Ip M, Li J, Lau JTF. Low uptake of HIV testing among male clients of female sex workers in China. AIDS Care. 2019;31(2):193–8.PubMed
55.
Xu W, Zheng Y, Kaufman MR. Predictors of recent HIV testing among Chinese men who have sex with men: a barrier perspective. AIDS Patient Care STDS. 2018;32(10):408–17.PubMedPubMedCentral
56.
Li R, Pan X, Ma Q, Wang H, He L, Jiang T, et al. Prevalence of prior HIV testing and associated factors among MSM in Zhejiang Province, China: a cross-sectional study. BMC Public Health. 2016;16(1):1152.PubMedPubMedCentral
57.
Wang Y, Li B, Zheng J, Sengupta S, Emrick CB, Cohen MS, et al. Factors related to female sex workers’ willingness to utilize VCT service: a qualitative study in Jinan city, northern China. AIDS Behav. 2009;13(5):866–72.PubMed
58.
Ma Q, Ono-Kihara M, Cong L, Pan X, Xu G, Zamani S, et al. Behavioral and psychosocial predictors of condom use among university students in Eastern China. AIDS care. 2009;21(2):249–59.PubMed
59.
Huang J, Bova C, Fennie KP, Rogers A, Williams AB. Knowledge, attitudes, behaviors, and perceptions of risk related to HIV/AIDS among Chinese university students in Hunan, China. AIDS Patient Care & STDs. 2005;19(11):769–77.
60.
Lönn E, Sahlholm K, Maimaiti R, Abdukarim K, Andersson R. A traditional society in change encounters HIV/AIDS: knowledge, attitudes, and risk behavior among students in northwestern China. AIDS patient care and STDS. 2007;21(1):48–56.PubMed
61.
Liu Y, Qian HZ, Ruan Y, et al. Frequent HIV testing: impact on HIV risk among Chinese men who have sex with men. J Acquir Immune Defic Syndr. 2016;72(4):452–61.PubMedPubMedCentral
62.
Zou H, Wu Z, Yu J, Li M, Ablimit M, Li F, et al. Internet-facilitated, voluntary counseling and testing (VCT) clinic-based HIV testing among men who have sex with men in China. PLoS One. 2013;8(2):e51919.PubMedPubMedCentral
63.
Liu Y, Wang J, Qian H-Z, et al. Seeking male sexual partners via internet and traditional venues among Chinese men who have sex with men: implications for HIV risk reduction interventions. AIDS and Behavior. 2016;20(10):2222–30.PubMedPubMedCentral
64.
Zhu X, Zhang W, Operario D, et al. Effects of a mobile health intervention to promote HIV self-testing with MSM in China: a randomized controlled trial. AIDS and behavior. 2019:1–11.
65.
Bien CH, Best JM, Muessig KE, Wei C, Han L, Tucker JD. Gay apps for seeking sex partners in China: implications for MSM sexual health. AIDS and Behavior. 2015;19(6):941–6.PubMedPubMedCentral
66.
Tang W, Best J, Zhang Y, et al. Gay mobile apps and the evolving virtual risk environment: a cross-sectional online survey among men who have sex with men in China. Sex Transm Infect. 2016;92(7):508–14.PubMed
67.
Han L, Candidate B, Bien CH, et al. HIV self-testing among online MSM in China: implications for expanding HIV testing among key populations. Journal of acquired immune deficiency syndromes (1999). 2014;67(2):216.
68.
Yan H, Yang H, Raymond HF, Li J, Shi LE, Huan X, et al. Experiences and correlates of HIV self-testing among men who have sex with men in Jiangsu province. China. AIDS and Behavior. 2015;19(3):485–91.PubMed
69.
Marley G, Kang D, Wilson EC, et al. Introducing rapid oral–fluid HIV testing among high risk populations in Shandong, China: feasibility and challenges. BMC public health. 2014;14(1):422.PubMedPubMedCentral
70.
Wang L, Podson D, Chen Z, Lu H, Wang V, Shepard C, et al. Using social media to increase HIV testing among men who have sex with men - Beijing, China, 2013-2017. MMWR Morb Mortal Wkly Rep. 2019;68(21):478–82.PubMedPubMedCentral
71.
Yan H, Zhang R, Wei C, Li J, Xu J, Yang H, et al. A peer-led, community-based rapid HIV testing intervention among untested men who have sex with men in China: an operational model for expansion of HIV testing and linkage to care. Sex Transm Infect. 2014;90(5):388–93.PubMed
72.
Li S, Huang H, Cai Y, Ye X, Shen X, Shi R, et al. Evaluation of a school-based HIV/AIDS peer-led prevention programme: the first intervention trial for children of migrant workers in China. Int J STD AIDS. 2010;21(2):82–6.PubMed
73.
Zhang C, Li X, Brecht ML, Koniak-Griffin D. Can self-testing increase HIV testing among men who have sex with men: a systematic review and meta-analysis. PLoS One. 2017;12(11):e0188890.PubMedPubMedCentral
74.
Tao J, Li M-y, Qian H-Z, et al. Home-based HIV testing for men who have sex with men in China: a novel community-based partnership to complement government programs. PloS one. 2014;9(7):e102812.PubMedPubMedCentral
75.
Tang W, Han L, Best J, Zhang Y, Mollan K, Kim J, et al. Crowdsourcing HIV test promotion videos: a noninferiority randomized controlled trial in China. Clinical infectious diseases. 2016;62(11):1436–42.PubMedPubMedCentral
76.
Jiang Y, Qiu M, Zhang G, et al. Quality assurance in the HIV/AIDS laboratory network of China. International journal of epidemiology. 2010;39(suppl_2):ii72–8.PubMedPubMedCentral
77.
Zhang L, Chow EPF, Zhang J, Jing J, Wilson DP. Suppl 1: Describing the Chinese HIV surveillance system and the influences of political structures and social stigma. The open AIDS journal. 2012;6:163.PubMedPubMedCentral
78.
Tang H, Mao Y, Shi CX, Han J, Wang L, Xu J, et al. Baseline CD4 cell counts of newly diagnosed HIV cases in China: 2006–2012. PloS one. 2014;9(6):e96098.PubMedPubMedCentral
79.
Zhang D, Li C, Meng S, Qi J, Fu X, Sun J. Attrition of MSM with HIV/AIDS along the continuum of care from screening to CD4 testing in China. AIDS care. 2014;26(9):1118–21.PubMed
80.
Liu Y, Osborn CY, Qian H-Z, et al. Barriers and facilitators of linkage to and engagement in HIV care among HIV-positive men who have sex with men in China: a qualitative study. AIDS patient care and STDs. 2016;30(2):70–7.PubMedPubMedCentral
81.
Liu Y, Vermund SH, Ruan Y, et al. Peer counselling versus standard-of-care on reducing high-risk behaviours among newly diagnosed HIV-positive men who have sex with men in Beijing, China: a randomized intervention study. J Int AIDS Soc. 2018;21(2).PubMedCentral
82.
Wu Z, Zhao Y, Ge X, Mao Y, Tang Z, Shi CX, et al. Simplified HIV testing and treatment in China: analysis of mortality rates before and after a structural intervention. PLoS medicine. 2015;12(9):e1001874.PubMedPubMedCentral
83.
Zang X, Tang H, Min JE, Gu D, Montaner JS, Wu Z, et al. Cost-effectiveness of the ‘One4All’HIV linkage intervention in Guangxi Zhuang autonomous region. China. PloS one. 2016;11(11):e0167308.PubMed
84.
Zhong F, Tang W, Cheng W, Lin P, Wu Q, Cai Y, et al. Acceptability and feasibility of a social entrepreneurship testing model to promote HIV self-testing and linkage to care among men who have sex with men. HIV medicine. 2017;18(5):376–82.PubMed
85.
Xia Q, Zhong Y, Wiewel EW, Braunstein SL, Torian LV. Linkage to care after HIV diagnosis in New York City: better than we thought. JAIDS Journal of Acquired Immune Deficiency Syndromes. 2017;76(1):e18–21.PubMed
86.
Craw JA, Gardner LI, Marks G, Rapp RC, Bosshart J, Duffus WA, et al. Brief strengths-based case management promotes entry into HIV medical care: results of the antiretroviral treatment access study-II. JAIDS Journal of Acquired Immune Deficiency Syndromes. 2008;47(5):597–606.PubMed
87.
Gardner LI, Metsch LR, Anderson-Mahoney P, Loughlin AM, del Rio C, Strathdee S, et al. Efficacy of a brief case management intervention to link recently diagnosed HIV-infected persons to care. Aids. 2005;19(4):423–31.PubMed
88.
Molitor F, Waltermeyer J, Mendoza M, Kuenneth C, Aguirre A, Brockmann K, et al. Locating and linking to medical care HIV-positive persons without a history of care: findings from the California Bridge Project. AIDS care. 2006;18(5):456–9.PubMed
89.
Bradford JB, Coleman S, Cunningham W. HIV System Navigation: an emerging model to improve HIV care access. AIDS patient care and STDs. 2007;21(S1):S-49.
90.
Rajabiun S, Cabral H, Tobias C, Relf M. Program design and evaluation strategies for the Special Projects of National Significance Outreach Initiative. AIDS patient care and STDs. 2007;21(S1):S-9.
91.
Govindasamy D, Meghij J, Negussi EK, Baggaley RC, Ford N, Kranzer K. Interventions to improve or facilitate linkage to or retention in pre-ART (HIV) care and initiation of ART in low-and middle-income settings–a systematic review. Journal of the International AIDS Society. 2014;17(1):19032.PubMedPubMedCentral
92.
Zhu H, Napravnik S, Eron JJ, Cole SR, Ma Y, Wohl DA, et al. Decreasing excess mortality of HIV-infected patients initiating antiretroviral therapy: comparison with mortality in general population in China, 2003-2009. J Acquir Immune Defic Syndr. 2013;63(5):e150–7.PubMedPubMedCentral
93.
Zhang F, Dou Z, Ma Y, Zhang Y, Zhao Y, Zhao D, et al. Effect of earlier initiation of antiretroviral treatment and increased treatment coverage on HIV-related mortality in China: a national observational cohort study. Lancet Infect Dis. 2011;11(7):516–24.PubMed
94.
Zhao Y, Li C, Sun X, Mu W, McGoogan J, He Y, et al. Mortality and treatment outcomes of China’s National Pediatric antiretroviral therapy program. Clin Infect Dis. 2013;56(5):735–44.PubMed
95.
Jia Z, Mao Y, Zhang F, Ruan Y, Ma Y, Li J, et al. Antiretroviral therapy to prevent HIV transmission in serodiscordant couples in China (2003-11): a national observational cohort study. Lancet. 2013;382(9899):1195–203.PubMed
96.
Ma Y, Dou Z, Guo W, Mao Y, Zhang F, McGoogan J, et al. The human immunodeficiency virus care continuum in China: 1985-2015. Clin Infect Dis. 2018;66(6):833–9.PubMed
97.
Eisinger RW, Dieffenbach CW, Fauci AS. HIV viral load and transmissibility of HIV infection: undetectable equals untransmittable. JAMA. 2019;321(5):451–2.PubMed
98.
Muessig KE, McLaughlin MM, Nie JM, Cai W, Zheng H, Yang L, et al. Suboptimal antiretroviral therapy adherence among HIV-infected adults in Guangzhou. China. AIDS Care. 2014;26(8):988–95.PubMed
99.
Da W, Li X, Qiao S, Zhou Y, Shen Z. Antiretroviral therapy and mental health among people living with HIV/AIDS in China. Psychol Health Med. 2019:1–8.
100.
Zhou G, Li X, Qiao S, Shen Z, Zhou Y. Influence of side effects on ART adherence among PLWH in China: the moderator role of ART-related knowledge. AIDS Behav. 2018;22(3):961–70.PubMed
101.
Liu P, Liao L, Xu W, Yan J, Zuo Z, Leng X, et al. Adherence, virological outcome, and drug resistance in Chinese HIV patients receiving first-line antiretroviral therapy from 2011 to 2015. Medicine (Baltimore). 2018;97(50):e13555.PubMedPubMedCentral
102.
Huang Y, Huang X, Luo Y, et al. Assessing the efficacy of lopinavir/eitonavir-based preferred and alternative second-line regimens in HIV-infected patients: a meta-analysis of key evidence to support WHO recommendations. Front Pharmacol. 2018;9:890.PubMedPubMedCentral
103.
104.
Sweeney S, Obure CD, Maier CB, Greener R, Dehne K, Vassall A. Costs and efficiency of integrating HIV/AIDS services with other health services: a systematic review of evidence and experience. Sex Transm Infect. 2012;88(2):85–99.PubMed
105.
Sylla L, Bruce RD, Kamarulzaman A, Altice FL. Integration and co-location of HIV/AIDS, tuberculosis and drug treatment services. International Journal of Drug Policy. 2007;18(4):306–12.PubMed
106.
Hoang T, Goetz MB, Yano EM, Rossman B, Anaya HD, Knapp H, et al. The impact of integrated HIV care on patient health outcomes. Medical care. 2009;47(5):560–7.PubMedPubMedCentral
Metadata
Title
Interventions to improve the HIV continuum of care in China
Authors
Xiangjun Zhang
Na Wang
Sten H. Vermund
Huachun Zou
Xianhong Li
Fujie Zhang
Han-Zhu Qian
Publication date
01-12-2019
Publisher
Springer US
Published in
Current HIV/AIDS Reports / Issue 6/2019
Print ISSN: 1548-3568
Electronic ISSN: 1548-3576
DOI
https://doi.org/10.1007/s11904-019-00469-y

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Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

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Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

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