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Published in: Current Hepatology Reports 2/2019

01-06-2019 | Kidney Transplantation | Hepatitis C (H Vargas and S Flamm, Section Editors)

Hepatitis C-Positive Organs for Liver and Kidney Transplantation—Emerging Data and Current Management Strategies

Authors: Blanca C. Lizaola-Mayo, Hugo E. Vargas, David M. Chascsa

Published in: Current Hepatology Reports | Issue 2/2019

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Abstract

Purpose of Review

We aim to review the current guidelines and emerging data and compare the pros and cons for the use of HCV-positive organs.

Recent Findings

Some recent data suggests that the use of HCV-positive livers and kidneys safely increases the organ pool, additionally reducing wait list time, healthcare costs, and mortality.

Summary

Despite this therapeutic breakthrough, the demand for organs and waitlist mortality remains high. Every year, thousands of viable hepatitis C-positive organs are discarded. The emerging data regarding transplantation of HCV-positive organs is promising; however, further research is warranted with larger samples. A literature search was conducted using PubMed, using the keywords “transplant recipients,” “hepatitis C,” “kidney transplantation,” “liver transplantation,” “direct acting antivirals,” and “pre transplant.” Only articles in the English language were included.
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Metadata
Title
Hepatitis C-Positive Organs for Liver and Kidney Transplantation—Emerging Data and Current Management Strategies
Authors
Blanca C. Lizaola-Mayo
Hugo E. Vargas
David M. Chascsa
Publication date
01-06-2019
Publisher
Springer US
Published in
Current Hepatology Reports / Issue 2/2019
Electronic ISSN: 2195-9595
DOI
https://doi.org/10.1007/s11901-019-00465-1

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