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Current Diabetes Reports

Published in:

01-10-2021 | Glaucoma | Microvascular Complications—Retinopathy (R Channa, Section Editor)

Association Between Diabetes, Diabetic Retinopathy, and Glaucoma

Authors: Yangjiani Li, William Mitchell, Tobias Elze, Nazlee Zebardast

Published in: Current Diabetes Reports | Issue 10/2021

Abstract

Purpose of Review

The strength of the relationship between diabetes, diabetic retinopathy (DR), and glaucoma remains controversial. We review evidence supporting and refuting this association and explore mechanistic pathological and treatment relationships linking these diseases.

Recent Findings

While studies have shown diabetes/DR may increase the risk for glaucoma, this remains inconsistently demonstrated. Diabetes/DR may contribute toward glaucomatous optic neuropathy indirectly (either by increasing intraocular pressure or vasculopathy) or through direct damage to the optic nerve. However, certain elements of diabetes may slow glaucoma progression, and diabetic treatment may concurrently be beneficial in glaucoma management. Diabetes plays a significant role in poor outcomes after glaucoma surgery.

Summary

While the relationship between diabetes/DR and glaucoma remains controversial, multiple mechanistic links connecting pathophysiology and management of diabetes, DR, and glaucoma have been made. However, a deeper understanding of the causes of disease association is needed.

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Title: Association Between Diabetes, Diabetic Retinopathy, and Glaucoma
Authors: Yangjiani Li
William Mitchell
Tobias Elze
Nazlee Zebardast
Publication date: 01-10-2021
Publisher: Springer US
Keywords: Glaucoma
Diabetic Retinopathy
Diabetic Retinopathy
Published in: Current Diabetes Reports / Issue 10/2021
Print ISSN: 1534-4827
Electronic ISSN: 1539-0829
DOI: https://doi.org/10.1007/s11892-021-01404-5

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Association Between Diabetes, Diabetic Retinopathy, and Glaucoma

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