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Published in: Current Cardiology Reports 7/2022

07-05-2022 | Systemic Lupus Erythematosus | Women and Cardiovascular Health (N Goldberg and S Lewis, Section Editors)

Assessment of Cardiac Risk in Women with Autoimmune Disease

Authors: Tyler Schmidt, Rekha Mankad

Published in: Current Cardiology Reports | Issue 7/2022

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Abstract

Purpose of Review

The purpose of our review was to evaluate current standards in clinical practice in determining overall cardiac risk in female patients with chronic rheumatologic diseases. We hoped to not only summarize known cardiac manifestations of various chronic rheumatologic diseases but also determine the effectiveness of new risk scores in determining cardiac risk in this patient population.

Recent Findings

Chronic rheumatologic diseases have been associated with various cardiac manifestations for some time, with initial studies involving risk of coronary artery disease (CAD) in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). However, recent studies have shown numerous other cardiac manifestations associated with these and other chronic rheumatologic diseases. Risk scores have been used for several decades to help determine overall cardiac risk in the general population, but these risk scores have notoriously underestimated the risk of cardiac disease in woman and in patients with chronic rheumatologic diseases. These diseases, often with a female predominance, can impact long-term mortality and have devastating consequences if not monitored and treated appropriately. Thus, new risk scores have been developed over the last several years to help improve detection and awareness of cardiac disease in these patients.

Summary

Novel modified risk scores have found some success at improving the detection of cardiac disease in patients with chronic rheumatologic diseases. Further studies looking at these risk scores need to determine the accuracy of these scores and where they fall short. With the advent of advanced imaging technologies, future risk scores may involve certain imaging-based markers to help guide accurate risk determination.
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Metadata
Title
Assessment of Cardiac Risk in Women with Autoimmune Disease
Authors
Tyler Schmidt
Rekha Mankad
Publication date
07-05-2022
Publisher
Springer US
Published in
Current Cardiology Reports / Issue 7/2022
Print ISSN: 1523-3782
Electronic ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-022-01698-1

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