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Current Cardiology Reports

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01-02-2020 | Sleep Apnea | Hypertension (DS Geller and DL Cohen, Section Editors)

Obstructive Sleep Apnea, Hypertension, and Cardiovascular Risk: Epidemiology, Pathophysiology, and Management

Authors: Liann Abu Salman, Rachel Shulman, Jordana B. Cohen

Published in: Current Cardiology Reports | Issue 2/2020

Abstract

Purpose of Review

Given the rising prevalence of obstructive sleep apnea (OSA), we aimed to review the epidemiologic and pathophysiologic relationship of OSA, hypertension, and cardiovascular disease, and to summarize recent advances in the treatment of OSA.

Recent Findings

OSA is associated with an elevated risk of hypertension and cardiovascular disease. Several pathophysiologic factors contribute to the relationship between OSA and vascular risk, including neurohormonal dysregulation, endothelial dysfunction, and inflammation. While CPAP reduces blood pressure, it has not been demonstrated to reduce cardiovascular risk. The combination of CPAP and weight loss has a synergistic effect on blood pressure and several metabolic parameters. Adherence to CPAP is poor across studies, potentially contributing to the attenuation of perceived cardiovascular benefit from CPAP therapy.

Summary

A greater emphasis on adherence to CPAP and the combination of CPAP and weight loss are central to reducing cardiovascular risk among individuals with OSA.

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Title: Obstructive Sleep Apnea, Hypertension, and Cardiovascular Risk: Epidemiology, Pathophysiology, and Management
Authors: Liann Abu Salman
Rachel Shulman
Jordana B. Cohen
Publication date: 01-02-2020
Publisher: Springer US
Keywords: Sleep Apnea
Obesity
Obesity
Hypertension
Hypertension
Published in: Current Cardiology Reports / Issue 2/2020
Print ISSN: 1523-3782
Electronic ISSN: 1534-3170
DOI: https://doi.org/10.1007/s11886-020-1257-y

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Keynote webinar | Spotlight on medication adherence

Springer Medicine

Obstructive Sleep Apnea, Hypertension, and Cardiovascular Risk: Epidemiology, Pathophysiology, and Management

Abstract

Purpose of Review

Recent Findings

Summary

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Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

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Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose of Review

Recent Findings

Summary

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