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Current Cardiology Reports

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01-12-2020 | Sarcoidosis | Heart Failure (HJ Eisen, Section Editor)

Sarcoid Heart Disease: an Update on Diagnosis and Management

Authors: Sofia Carolina Masri, Lavanya Bellumkonda

Published in: Current Cardiology Reports | Issue 12/2020

Abstract

Purpose of Review

The purpose of this review is to provide an update on cardiac sarcoidosis (CS) and to discuss the current recommendations and progress in diagnosis and management of this disease. Sarcoidosis is a multisystem granulomatous disease of unknown etiology. Cardiac involvement is seen in at least 25% and is associated with poor prognosis. Manifestations of cardiac sarcoidosis (CS) can vary from presence of silent myocardial granulomas, which may lead to sudden death, to symptomatic conduction abnormalities, ventricular arrhythmias, and heart failure.

Recent Findings

We discuss newer imaging modalities such as cardiac magnetic resonance imaging and positron emission tomography in conjunction with clinical criteria increasingly used for diagnosing and prognosticating patients with CS. Immunosuppression (primarily corticosteroids) is recommended for treatment of CS; however, its efficacy has never been proven in prospective randomized studies. The role of imaging to guide the use of immunotherapy is unknown.

Summary

Cardiac sarcoidosis continues to challenge clinicians due to its protean presentations, lack of diagnostic standards, and data for risk stratification and treatment. There is a need for prospective, randomized controlled trials to understand how best to diagnose and treat cardiac sarcoidosis.

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Title: Sarcoid Heart Disease: an Update on Diagnosis and Management
Authors: Sofia Carolina Masri
Lavanya Bellumkonda
Publication date: 01-12-2020
Publisher: Springer US
Keywords: Sarcoidosis
Sarcoidosis
Ventricular Tachycardia
Positron Emission Tomography
Published in: Current Cardiology Reports / Issue 12/2020
Print ISSN: 1523-3782
Electronic ISSN: 1534-3170
DOI: https://doi.org/10.1007/s11886-020-01429-4

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