Skip to main content
Top
Published in: Current Cardiology Reports 11/2018

01-11-2018 | Interventional Cardiology (SR Bailey, Section Editor)

Transcatheter Mitral Valve Therapy: Defining the Patient Who Will Benefit

Authors: Marvin H. Eng, Dee Dee Wang

Published in: Current Cardiology Reports | Issue 11/2018

Login to get access

Abstract

Purpose of Review

This report aims to define the clinical and anatomic variables key in determining patient suitability for transcatheter mitral valve therapies.

Recent Findings

Candidacy for transcatheter mitral valve repair requires weighing the clinical variables that may impact the ability to improve patient symptoms and prolong survival that include left ventricular ejection fraction, symptom severity, pulmonary hypertension, and magnitude of residual regurgitation or stenosis. Individualized selection of transcatheter repair or replacement based on patho-anatomy is being explored. The primary goal is achieving significant reduction in mitral regurgitation.

Summary

Transcatheter mitral valve replacement requires rigorous anatomic screening using computed tomography and candidates should be able to take oral anticoagulation. Selection of patients for transcatheter mitral valve repair is complex and requires intimate knowledge of clinical variables and specific device limitations.
Literature
1.
go back to reference Nkomo VT, Gardin JM, Skelton TN, Gottdiener JS, Scott CG, Enriquez-Sarano M. Burden of valvular heart diseases: a population-based study. Lancet. 2006;368:1005–11.CrossRef Nkomo VT, Gardin JM, Skelton TN, Gottdiener JS, Scott CG, Enriquez-Sarano M. Burden of valvular heart diseases: a population-based study. Lancet. 2006;368:1005–11.CrossRef
2.
go back to reference Dziadzko V, Clavel M-A, Dziadzko M, et al. Outcome and undertreatment of mitral regurgitation: a community cohort study. Lancet. 2018;391:960–9.CrossRef Dziadzko V, Clavel M-A, Dziadzko M, et al. Outcome and undertreatment of mitral regurgitation: a community cohort study. Lancet. 2018;391:960–9.CrossRef
3.
go back to reference Monteagudo Ruiz JM, Galderisi M, Buonauro A, et al. Overview of mitral regurgitation in Europe: results from the European Registry of mitral regurgitation (EuMiClip). Eur Heart J Cardiovasc Imaging 2018:jey011-jey. Monteagudo Ruiz JM, Galderisi M, Buonauro A, et al. Overview of mitral regurgitation in Europe: results from the European Registry of mitral regurgitation (EuMiClip). Eur Heart J Cardiovasc Imaging 2018:jey011-jey.
4.
go back to reference Regueiro A, Granada JF, Dagenais F, Rodés-Cabau J. Transcatheter mitral valve replacement: insights from early clinical experience and future challenges. J Am Coll Cardiol. 2017;69:2175–92.CrossRef Regueiro A, Granada JF, Dagenais F, Rodés-Cabau J. Transcatheter mitral valve replacement: insights from early clinical experience and future challenges. J Am Coll Cardiol. 2017;69:2175–92.CrossRef
5.
go back to reference Maisano F, Alfieri O, Banai S, et al. The future of transcatheter mitral valve interventions: competitive or complementary role of repair vs. replacement? Eur Heart J. 2015;36:1651–9.CrossRef Maisano F, Alfieri O, Banai S, et al. The future of transcatheter mitral valve interventions: competitive or complementary role of repair vs. replacement? Eur Heart J. 2015;36:1651–9.CrossRef
6.
go back to reference Ling LH, Enriquez-Sarano M, Seward JB, et al. Early surgery in patients with mitral regurgitation due to flail leaflets: a long-term outcome study. Circulation. 1997;96:1819–25.CrossRef Ling LH, Enriquez-Sarano M, Seward JB, et al. Early surgery in patients with mitral regurgitation due to flail leaflets: a long-term outcome study. Circulation. 1997;96:1819–25.CrossRef
7.
go back to reference Suri RM, Schaff HV, Enriquez-Sarano M. Mitral valve repair in asymptomatic patients with severe mitral regurgitation: pushing past the tipping point. Semin Thorac Cardiovasc Surg. 2014;26:95–101.CrossRef Suri RM, Schaff HV, Enriquez-Sarano M. Mitral valve repair in asymptomatic patients with severe mitral regurgitation: pushing past the tipping point. Semin Thorac Cardiovasc Surg. 2014;26:95–101.CrossRef
8.
go back to reference Ghoreishi M, Evans CF, DeFilippi CR, et al. Pulmonary hypertension adversely affects short- and long-term survival after mitral valve operation for mitral regurgitation: Implications for timing of surgery. J Thorac Cardiovasc Surg. 142:1439–52.CrossRef Ghoreishi M, Evans CF, DeFilippi CR, et al. Pulmonary hypertension adversely affects short- and long-term survival after mitral valve operation for mitral regurgitation: Implications for timing of surgery. J Thorac Cardiovasc Surg. 142:1439–52.CrossRef
9.
go back to reference Asgar AW, Mack MJ, Stone GW. Secondary mitral regurgitation in heart failure: pathophysiology, prognosis, and therapeutic considerations. J Am Coll Cardiol. 2015;65:1231–48.CrossRef Asgar AW, Mack MJ, Stone GW. Secondary mitral regurgitation in heart failure: pathophysiology, prognosis, and therapeutic considerations. J Am Coll Cardiol. 2015;65:1231–48.CrossRef
10.
go back to reference Bach DS, Bolling SF. Improvement following correction of secondary mitral regurgitation in end-stage cardiomyopathy with mitral annuloplasty. Am J Cardiol. 1996;78:966–9.CrossRef Bach DS, Bolling SF. Improvement following correction of secondary mitral regurgitation in end-stage cardiomyopathy with mitral annuloplasty. Am J Cardiol. 1996;78:966–9.CrossRef
11.
go back to reference Wu AH, Aaronson KD, Bolling SF, Pagani FD, Welch K, Koelling TM. Impact of mitral valve annuloplasty on mortality risk in patients with mitral regurgitation and left ventricular systolic dysfunction. J Am Coll Cardiol. 2005;45:381–7.CrossRef Wu AH, Aaronson KD, Bolling SF, Pagani FD, Welch K, Koelling TM. Impact of mitral valve annuloplasty on mortality risk in patients with mitral regurgitation and left ventricular systolic dysfunction. J Am Coll Cardiol. 2005;45:381–7.CrossRef
12.
go back to reference Goldstein D, Moskowitz AJ, Gelijns AC, et al. Two-year outcomes of surgical treatment of severe ischemic mitral regurgitation. N Engl J Med. 2016;374:344–53.CrossRef Goldstein D, Moskowitz AJ, Gelijns AC, et al. Two-year outcomes of surgical treatment of severe ischemic mitral regurgitation. N Engl J Med. 2016;374:344–53.CrossRef
13.
go back to reference Rossi A, Dini FL, Faggiano P, et al. Independent prognostic value of functional mitral regurgitation in patients with heart failure. A quantitative analysis of 1256 patients with ischaemic and non-ischaemic dilated cardiomyopathy. Heart. 2011;97:1675–80.CrossRef Rossi A, Dini FL, Faggiano P, et al. Independent prognostic value of functional mitral regurgitation in patients with heart failure. A quantitative analysis of 1256 patients with ischaemic and non-ischaemic dilated cardiomyopathy. Heart. 2011;97:1675–80.CrossRef
14.
go back to reference de Marchena E, Badiye A, Robalino G, et al. Respective prevalence of the different carpentier classes of mitral regurgitation: a stepping stone for future therapeutic research and development. J Card Surg. 2011;26:385–92.CrossRef de Marchena E, Badiye A, Robalino G, et al. Respective prevalence of the different carpentier classes of mitral regurgitation: a stepping stone for future therapeutic research and development. J Card Surg. 2011;26:385–92.CrossRef
15.
go back to reference Giannini C, Fiorelli F, De Carlo M, et al. Comparison of percutaneous mitral valve repair versus conservative treatment in severe functional mitral regurgitation. Am J Cardiol. 2016;117:271–7.CrossRef Giannini C, Fiorelli F, De Carlo M, et al. Comparison of percutaneous mitral valve repair versus conservative treatment in severe functional mitral regurgitation. Am J Cardiol. 2016;117:271–7.CrossRef
16.
go back to reference D'Ascenzo F, Moretti C, Marra WG, et al. Meta-analysis of the usefulness of Mitraclip in patients with functional mitral regurgitation. Am J Cardiol. 2015;116:325–31.CrossRef D'Ascenzo F, Moretti C, Marra WG, et al. Meta-analysis of the usefulness of Mitraclip in patients with functional mitral regurgitation. Am J Cardiol. 2015;116:325–31.CrossRef
17.
go back to reference Nishimura RA, Otto CM, Bonow RO, et al. 2014 AHA/ACC guideline for the Management of Patients with Valvular Heart Disease: executive summary: a report of the American College of Cardiology/American Heart Association task force on practice guidelines. Circulation. 2014;129:2440–92.CrossRef Nishimura RA, Otto CM, Bonow RO, et al. 2014 AHA/ACC guideline for the Management of Patients with Valvular Heart Disease: executive summary: a report of the American College of Cardiology/American Heart Association task force on practice guidelines. Circulation. 2014;129:2440–92.CrossRef
18.
go back to reference Azzalini L, Millan X, Khan R, et al. Impact of left ventricular function on clinical outcomes of functional mitral regurgitation patients undergoing transcatheter mitral valve repair. Catheter Cardiovasc Interv. 2016;88:1124–33.CrossRef Azzalini L, Millan X, Khan R, et al. Impact of left ventricular function on clinical outcomes of functional mitral regurgitation patients undergoing transcatheter mitral valve repair. Catheter Cardiovasc Interv. 2016;88:1124–33.CrossRef
19.
go back to reference Puls M, Lubos E, Boekstegers P, et al. One-year outcomes and predictors of mortality after MitraClip therapy in contemporary clinical practice: results from the German transcatheter mitral valve interventions registry. Eur Heart J. 2016;37:703–12.CrossRef Puls M, Lubos E, Boekstegers P, et al. One-year outcomes and predictors of mortality after MitraClip therapy in contemporary clinical practice: results from the German transcatheter mitral valve interventions registry. Eur Heart J. 2016;37:703–12.CrossRef
20.
go back to reference Rudolph V, Lubos E, Schluter M, et al. Aetiology of mitral regurgitation differentially affects 2-year adverse outcomes after MitraClip therapy in high-risk patients. Eur J Heart Fail. 2013;15:796–807.CrossRef Rudolph V, Lubos E, Schluter M, et al. Aetiology of mitral regurgitation differentially affects 2-year adverse outcomes after MitraClip therapy in high-risk patients. Eur J Heart Fail. 2013;15:796–807.CrossRef
21.
go back to reference Bozdag-Turan I, Paranskaya L, Birkemeyer R, et al. Percutaneous mitral repair with the MitraClip system in patients with mild-to-moderate and severe heart failure: a single-Centre experience. Cardiovasc Ther. 2014;32:66–73.CrossRef Bozdag-Turan I, Paranskaya L, Birkemeyer R, et al. Percutaneous mitral repair with the MitraClip system in patients with mild-to-moderate and severe heart failure: a single-Centre experience. Cardiovasc Ther. 2014;32:66–73.CrossRef
22.
go back to reference Geis NA, Puls M, Lubos E, et al. Safety and efficacy of MitraClip therapy in patients with severely impaired left ventricular ejection fraction: results from the German transcatheter mitral valve interventions (TRAMI) registry. Eur J Heart Fail. 2018;20:598–608.CrossRef Geis NA, Puls M, Lubos E, et al. Safety and efficacy of MitraClip therapy in patients with severely impaired left ventricular ejection fraction: results from the German transcatheter mitral valve interventions (TRAMI) registry. Eur J Heart Fail. 2018;20:598–608.CrossRef
23.
go back to reference Lesevic H, Sonne C, Braun D, et al. Acute and midterm outcome after MitraClip therapy in patients with severe mitral regurgitation and left ventricular dysfunction. Am J Cardiol. 2015;116:749–56.CrossRef Lesevic H, Sonne C, Braun D, et al. Acute and midterm outcome after MitraClip therapy in patients with severe mitral regurgitation and left ventricular dysfunction. Am J Cardiol. 2015;116:749–56.CrossRef
24.
go back to reference Melisurgo G, Ajello S, Pappalardo F, et al. Afterload mismatch after MitraClip insertion for functional mitral regurgitation. Am J Cardiol. 2014;113:1844–50.CrossRef Melisurgo G, Ajello S, Pappalardo F, et al. Afterload mismatch after MitraClip insertion for functional mitral regurgitation. Am J Cardiol. 2014;113:1844–50.CrossRef
25.
go back to reference Schau T, Isotani A, Neuss M, et al. Long-term survival after MitraClip<sup>&#xae;</sup> therapy in patients with severe mitral regurgitation and severe congestive heart failure: A comparison among survivals predicted by heart failure models. J Cardiol. 2016;67:287–94.CrossRef Schau T, Isotani A, Neuss M, et al. Long-term survival after MitraClip<sup>&#xae;</sup> therapy in patients with severe mitral regurgitation and severe congestive heart failure: A comparison among survivals predicted by heart failure models. J Cardiol. 2016;67:287–94.CrossRef
26.
go back to reference Varghese R, Itagaki S, Anyanwu AC, Milla F, Adams DH. Predicting early left ventricular dysfunction after mitral valve&#xa0;reconstruction: The effect of atrial fibrillation and pulmonary hypertension. J Thorac Cardiovasc Surg. 2014;148:422–7.CrossRef Varghese R, Itagaki S, Anyanwu AC, Milla F, Adams DH. Predicting early left ventricular dysfunction after mitral valve&#xa0;reconstruction: The effect of atrial fibrillation and pulmonary hypertension. J Thorac Cardiovasc Surg. 2014;148:422–7.CrossRef
27.
go back to reference Wang J, Han J, Li Y, et al. Preoperative risk factors of medium-term mitral valve repair outcome. Interact Cardiovasc Thorac Surg. 2014;19:946–54.CrossRef Wang J, Han J, Li Y, et al. Preoperative risk factors of medium-term mitral valve repair outcome. Interact Cardiovasc Thorac Surg. 2014;19:946–54.CrossRef
28.
go back to reference Murashita T, Okada Y, Kanemitsu H, et al. The impact of preoperative and postoperative pulmonary hypertension on long-term surgical outcome after mitral valve repair for degenerative mitral regurgitation. Ann Thorac Cardiovasc Surg. 2015;21:53–8.CrossRef Murashita T, Okada Y, Kanemitsu H, et al. The impact of preoperative and postoperative pulmonary hypertension on long-term surgical outcome after mitral valve repair for degenerative mitral regurgitation. Ann Thorac Cardiovasc Surg. 2015;21:53–8.CrossRef
29.
go back to reference Yzeiraj E, Bijuklic K, Tiburtius C, et al. Tricuspid regurgitation is a predictor of mortality after percutaneous mitral valve edge-to-edge repair. EuroIntervention. 2017;12:e1817–e24.CrossRef Yzeiraj E, Bijuklic K, Tiburtius C, et al. Tricuspid regurgitation is a predictor of mortality after percutaneous mitral valve edge-to-edge repair. EuroIntervention. 2017;12:e1817–e24.CrossRef
30.
go back to reference Tigges E, Blankenberg S, von Bardeleben RS, et al. Implication of pulmonary hypertension in patients undergoing MitraClip therapy: results from the German transcatheter mitral valve interventions (TRAMI) registry. Eur J Heart Fail. 2018;20:585–94.CrossRef Tigges E, Blankenberg S, von Bardeleben RS, et al. Implication of pulmonary hypertension in patients undergoing MitraClip therapy: results from the German transcatheter mitral valve interventions (TRAMI) registry. Eur J Heart Fail. 2018;20:585–94.CrossRef
31.
go back to reference Barth S, Hautmann MB, Kerber S, et al. Hemodynamic improvement at three months after MitraClipA(R) treatment in end-stage heart failure patients with functional mitral regurgitation. J Heart Valve Dis. 2016;25:475–82.PubMed Barth S, Hautmann MB, Kerber S, et al. Hemodynamic improvement at three months after MitraClipA(R) treatment in end-stage heart failure patients with functional mitral regurgitation. J Heart Valve Dis. 2016;25:475–82.PubMed
32.
go back to reference Dini FL, Conti U, Fontanive P, et al. Right ventricular dysfunction is a major predictor of outcome in patients with moderate to severe mitral regurgitation and left ventricular dysfunction. Am Heart J. 2007;154:172–9.CrossRef Dini FL, Conti U, Fontanive P, et al. Right ventricular dysfunction is a major predictor of outcome in patients with moderate to severe mitral regurgitation and left ventricular dysfunction. Am Heart J. 2007;154:172–9.CrossRef
33.
go back to reference •• Sorajja P, Vemulapalli S, Feldman T, et al. Outcomes with Transcatheter mitral valve repair in the United States: an STS/ACC TVT registry report. J Am Coll Cardiol. 2017;70:2315–27. This publication provides the most contemporary data regarding transcatheter mitral valve repair. CrossRef •• Sorajja P, Vemulapalli S, Feldman T, et al. Outcomes with Transcatheter mitral valve repair in the United States: an STS/ACC TVT registry report. J Am Coll Cardiol. 2017;70:2315–27. This publication provides the most contemporary data regarding transcatheter mitral valve repair. CrossRef
34.
go back to reference Toyama K, Ayabe K, Kar S, et al. Postprocedural changes of tricuspid regurgitation after MitraClip therapy for mitral regurgitation. Am J Cardiol. 2017;120:857–61.CrossRef Toyama K, Ayabe K, Kar S, et al. Postprocedural changes of tricuspid regurgitation after MitraClip therapy for mitral regurgitation. Am J Cardiol. 2017;120:857–61.CrossRef
35.
go back to reference Ohno Y, Attizzani GF, Capodanno D, et al. Association of tricuspid regurgitation with clinical and echocardiographic outcomes after percutaneous mitral valve repair with the MitraClip system: 30-day and 12-month follow-up from the GRASP registry. Eur Heart J Cardiovasc Imaging. 2014;15:1246–55.CrossRef Ohno Y, Attizzani GF, Capodanno D, et al. Association of tricuspid regurgitation with clinical and echocardiographic outcomes after percutaneous mitral valve repair with the MitraClip system: 30-day and 12-month follow-up from the GRASP registry. Eur Heart J Cardiovasc Imaging. 2014;15:1246–55.CrossRef
36.
go back to reference Frangieh AH, Gruner C, Mikulicic F, et al. Impact of percutaneous mitral valve repair using the MitraClip system on tricuspid regurgitation. EuroIntervention. 2016;11:e1680–e6.CrossRef Frangieh AH, Gruner C, Mikulicic F, et al. Impact of percutaneous mitral valve repair using the MitraClip system on tricuspid regurgitation. EuroIntervention. 2016;11:e1680–e6.CrossRef
37.
go back to reference Pighi M, Estevez-Loureiro R, Maisano F, et al. Immediate and 12-month outcomes of ischemic versus nonischemic functional mitral regurgitation in patients treated with MitraClip (from the 2011 to 2012 pilot sentinel registry of percutaneous edge-to-edge mitral valve repair of the European Society of Cardiology). Am J Cardiol. 2017;119:630–7.CrossRef Pighi M, Estevez-Loureiro R, Maisano F, et al. Immediate and 12-month outcomes of ischemic versus nonischemic functional mitral regurgitation in patients treated with MitraClip (from the 2011 to 2012 pilot sentinel registry of percutaneous edge-to-edge mitral valve repair of the European Society of Cardiology). Am J Cardiol. 2017;119:630–7.CrossRef
38.
go back to reference Leon MB, Smith CR, Mack MJ, et al. Transcatheter or surgical aortic-valve replacement in intermediate-risk patients. N Engl J Med. 2016;374:1609–20.CrossRef Leon MB, Smith CR, Mack MJ, et al. Transcatheter or surgical aortic-valve replacement in intermediate-risk patients. N Engl J Med. 2016;374:1609–20.CrossRef
39.
go back to reference Lee DH, Buth KJ, Martin BJ, Yip AM, Hirsch GM. Frail patients are at increased risk for mortality and prolonged institutional care after cardiac surgery. Circulation. 2010;121:973–8.CrossRef Lee DH, Buth KJ, Martin BJ, Yip AM, Hirsch GM. Frail patients are at increased risk for mortality and prolonged institutional care after cardiac surgery. Circulation. 2010;121:973–8.CrossRef
40.
go back to reference Metze C, Matzik A-S, Scherner M, et al. Impact of frailty on outcomes in patients undergoing percutaneous mitral valve repair. J Am Coll Cardiol Intv. 2017;10:1920–9.CrossRef Metze C, Matzik A-S, Scherner M, et al. Impact of frailty on outcomes in patients undergoing percutaneous mitral valve repair. J Am Coll Cardiol Intv. 2017;10:1920–9.CrossRef
41.
go back to reference Schafer U, Maisano F, Butter C, et al. Impact of Preprocedural left ventricular ejection fraction on 1-year outcomes after MitraClip implantation (from the ACCESS-EU phase I, a prospective, multicenter, nonrandomized Postapproval study of the MitraClip therapy in Europe). Am J Cardiol. 2016;118:873–80.CrossRef Schafer U, Maisano F, Butter C, et al. Impact of Preprocedural left ventricular ejection fraction on 1-year outcomes after MitraClip implantation (from the ACCESS-EU phase I, a prospective, multicenter, nonrandomized Postapproval study of the MitraClip therapy in Europe). Am J Cardiol. 2016;118:873–80.CrossRef
42.
go back to reference Feldman T, Foster E, Glower DD, et al. Percutaneous repair or surgery for mitral regurgitation. N Engl J Med. 2011;364:1395–406.CrossRef Feldman T, Foster E, Glower DD, et al. Percutaneous repair or surgery for mitral regurgitation. N Engl J Med. 2011;364:1395–406.CrossRef
43.
go back to reference Praz F, Spargias K, Chrissoheris M, et al. Compassionate use of the PASCAL transcatheter mitral valve repair system for patients with severe mitral regurgitation: a multicentre, prospective, observational, first-in-man study. Lancet. 2017;390:773–80.CrossRef Praz F, Spargias K, Chrissoheris M, et al. Compassionate use of the PASCAL transcatheter mitral valve repair system for patients with severe mitral regurgitation: a multicentre, prospective, observational, first-in-man study. Lancet. 2017;390:773–80.CrossRef
44.
go back to reference Lesevic H, Karl M, Braun D, et al. Long-term outcomes after MitraClip implantation according to the presence or absence of EVEREST inclusion criteria. Am J Cardiol. 2017;119:1255–61.CrossRef Lesevic H, Karl M, Braun D, et al. Long-term outcomes after MitraClip implantation according to the presence or absence of EVEREST inclusion criteria. Am J Cardiol. 2017;119:1255–61.CrossRef
45.
go back to reference Neuss M, Schau T, Isotani A, Pilz M, Schöpp M, Butter C. Elevated mitral valve pressure gradient after MitraClip implantation deteriorates long-term outcome in patients with severe mitral regurgitation and severe heart failure. J Am Coll Cardiol Intv. 2017;10:931–9.CrossRef Neuss M, Schau T, Isotani A, Pilz M, Schöpp M, Butter C. Elevated mitral valve pressure gradient after MitraClip implantation deteriorates long-term outcome in patients with severe mitral regurgitation and severe heart failure. J Am Coll Cardiol Intv. 2017;10:931–9.CrossRef
46.
go back to reference Cheng R, Dawkins S, Tat E, et al. Relation of residual mitral regurgitation despite elevated mitral gradients to risk of heart failure hospitalization after MitraClip repair. Am J Cardiol. 2017;120:1595–600.CrossRef Cheng R, Dawkins S, Tat E, et al. Relation of residual mitral regurgitation despite elevated mitral gradients to risk of heart failure hospitalization after MitraClip repair. Am J Cardiol. 2017;120:1595–600.CrossRef
47.
go back to reference Siminiak T, Wu JC, Haude M, et al. Treatment of functional mitral regurgitation by percutaneous annuloplasty: results of the TITAN trial. Eur J Heart Fail. 2012;14:931–8.CrossRef Siminiak T, Wu JC, Haude M, et al. Treatment of functional mitral regurgitation by percutaneous annuloplasty: results of the TITAN trial. Eur J Heart Fail. 2012;14:931–8.CrossRef
48.
go back to reference Lipiecki J, Siminiak T, Sievert H, et al. Coronary sinus-based percutaneous annuloplasty as treatment for functional mitral regurgitation: the TITAN II trial. Open Heart. 2016;3:e000411.CrossRef Lipiecki J, Siminiak T, Sievert H, et al. Coronary sinus-based percutaneous annuloplasty as treatment for functional mitral regurgitation: the TITAN II trial. Open Heart. 2016;3:e000411.CrossRef
49.
go back to reference Tops LF, Van de Veire NR, Schuijf JD, et al. Noninvasive evaluation of coronary sinus anatomy and its relation to the mitral valve annulus: implications for percutaneous mitral annuloplasty. Circulation. 2007;115:1426–32.CrossRef Tops LF, Van de Veire NR, Schuijf JD, et al. Noninvasive evaluation of coronary sinus anatomy and its relation to the mitral valve annulus: implications for percutaneous mitral annuloplasty. Circulation. 2007;115:1426–32.CrossRef
50.
go back to reference Kim J-H, Kocaturk O, Ozturk C, et al. Mitral cerclage Annuloplasty, a novel Transcatheter treatment for secondary mitral valve regurgitation: initial results in swine. J Am Coll Cardiol. 2009;54:638–51.CrossRef Kim J-H, Kocaturk O, Ozturk C, et al. Mitral cerclage Annuloplasty, a novel Transcatheter treatment for secondary mitral valve regurgitation: initial results in swine. J Am Coll Cardiol. 2009;54:638–51.CrossRef
51.
go back to reference Nickenig G, Hammerstingl C, Schueler R, et al. Transcatheter mitral Annuloplasty in chronic functional mitral regurgitation: 6-month results with the Cardioband percutaneous mitral repair system. J Am Coll Cardiol Intv. 2016;9:2039–47.CrossRef Nickenig G, Hammerstingl C, Schueler R, et al. Transcatheter mitral Annuloplasty in chronic functional mitral regurgitation: 6-month results with the Cardioband percutaneous mitral repair system. J Am Coll Cardiol Intv. 2016;9:2039–47.CrossRef
52.
go back to reference Muller DWM, Farivar RS, Jansz P, et al. Transcatheter mitral valve replacement for patients with symptomatic mitral regurgitation: a global feasibility trial. J Am Coll Cardiol. 2017;69:381–91.CrossRef Muller DWM, Farivar RS, Jansz P, et al. Transcatheter mitral valve replacement for patients with symptomatic mitral regurgitation: a global feasibility trial. J Am Coll Cardiol. 2017;69:381–91.CrossRef
53.
go back to reference Blackstone EH, Suri RM, Rajeswaran J, et al. Propensity-matched comparisons of clinical outcomes after transapical or transfemoral transcatheter aortic valve replacement: a placement of aortic transcatheter valves (PARTNER)-I trial substudy. Circulation. 2015;131:1989–2000.CrossRef Blackstone EH, Suri RM, Rajeswaran J, et al. Propensity-matched comparisons of clinical outcomes after transapical or transfemoral transcatheter aortic valve replacement: a placement of aortic transcatheter valves (PARTNER)-I trial substudy. Circulation. 2015;131:1989–2000.CrossRef
54.
go back to reference Ribeiro HB, Nombela-Franco L, Munoz-Garcia AJ, et al. Predictors and impact of myocardial injury after transcatheter aortic valve replacement: a multicenter registry. J Am Coll Cardiol. 2015;66:2075–88.CrossRef Ribeiro HB, Nombela-Franco L, Munoz-Garcia AJ, et al. Predictors and impact of myocardial injury after transcatheter aortic valve replacement: a multicenter registry. J Am Coll Cardiol. 2015;66:2075–88.CrossRef
55.
go back to reference • Wang DD, Eng MH, Greenbaum AB, et al. Validating a prediction modeling tool for left ventricular outflow tract (LVOT) obstruction after transcatheter mitral valve replacement (TMVR). Catheter Cardiovasc Interv 2017. Seminal work first describing the a minimum residual left ventricular outflow tract area before left ventricular outflow obstruction occurs.. • Wang DD, Eng MH, Greenbaum AB, et al. Validating a prediction modeling tool for left ventricular outflow tract (LVOT) obstruction after transcatheter mitral valve replacement (TMVR). Catheter Cardiovasc Interv 2017. Seminal work first describing the a minimum residual left ventricular outflow tract area before left ventricular outflow obstruction occurs..
56.
go back to reference Greenbaum AB, Condado JF, Eng M, et al. Long or redundant leaflet complicating transcatheter mitral valve replacement: case vignettes that advocate for removal or reduction of the anterior mitral leaflet. Catheter Cardiovasc Interv 2017. Greenbaum AB, Condado JF, Eng M, et al. Long or redundant leaflet complicating transcatheter mitral valve replacement: case vignettes that advocate for removal or reduction of the anterior mitral leaflet. Catheter Cardiovasc Interv 2017.
57.
go back to reference Babaliaros VC, Greenbaum AB, Khan JM, et al. Intentional percutaneous laceration of the anterior mitral leaflet to prevent outflow obstruction during Transcatheter mitral valve replacement: first-in-human experience. JACC Cardiovasc Interv. 2017;10:798–809.CrossRef Babaliaros VC, Greenbaum AB, Khan JM, et al. Intentional percutaneous laceration of the anterior mitral leaflet to prevent outflow obstruction during Transcatheter mitral valve replacement: first-in-human experience. JACC Cardiovasc Interv. 2017;10:798–809.CrossRef
58.
go back to reference Guerrero M, Wang DD, Himbert D, et al. Short-term results of alcohol septal ablation as a bail-out strategy to treat severe left ventricular outflow tract obstruction after transcatheter mitral valve replacement in patients with severe mitral annular calcification. Catheter Cardiovasc Interv. 2017;90:1220–6.CrossRef Guerrero M, Wang DD, Himbert D, et al. Short-term results of alcohol septal ablation as a bail-out strategy to treat severe left ventricular outflow tract obstruction after transcatheter mitral valve replacement in patients with severe mitral annular calcification. Catheter Cardiovasc Interv. 2017;90:1220–6.CrossRef
59.
go back to reference Cheung A, Webb JG, Barbanti M, et al. 5-year experience with transcatheter transapical mitral valve-in-valve implantation for bioprosthetic valve dysfunction. J Am Coll Cardiol. 2013;61:1759–66.CrossRef Cheung A, Webb JG, Barbanti M, et al. 5-year experience with transcatheter transapical mitral valve-in-valve implantation for bioprosthetic valve dysfunction. J Am Coll Cardiol. 2013;61:1759–66.CrossRef
60.
go back to reference Ye J, Cheung A, Yamashita M, et al. Transcatheter aortic and mitral valve-in-valve implantation for failed surgical bioprosthetic valves: an 8-year single-center experience. JACC Cardiovasc Interv. 2015;8:1735–44.CrossRef Ye J, Cheung A, Yamashita M, et al. Transcatheter aortic and mitral valve-in-valve implantation for failed surgical bioprosthetic valves: an 8-year single-center experience. JACC Cardiovasc Interv. 2015;8:1735–44.CrossRef
61.
go back to reference Whisenant B, Jones K, Miller D, Horton S, Miner E. Thrombosis following mitral and tricuspid valve-in-valve replacement. J Thorac Cardiovasc Surg. 2015;149:e26–9.CrossRef Whisenant B, Jones K, Miller D, Horton S, Miner E. Thrombosis following mitral and tricuspid valve-in-valve replacement. J Thorac Cardiovasc Surg. 2015;149:e26–9.CrossRef
62.
go back to reference Eng MH, Greenbaum A, Wang DD, et al. Thrombotic valvular dysfunction with transcatheter mitral interventions for postsurgical failures. Catheter Cardiovasc Interv. 2017;90:321–8.CrossRef Eng MH, Greenbaum A, Wang DD, et al. Thrombotic valvular dysfunction with transcatheter mitral interventions for postsurgical failures. Catheter Cardiovasc Interv. 2017;90:321–8.CrossRef
63.
go back to reference Butnaru A, Shaheen J, Tzivoni D, Tauber R, Bitran D, Silberman S. Diagnosis and treatment of early bioprosthetic malfunction in the mitral valve position due to thrombus formation. Am J Cardiol. 2013;112:1439–44.CrossRef Butnaru A, Shaheen J, Tzivoni D, Tauber R, Bitran D, Silberman S. Diagnosis and treatment of early bioprosthetic malfunction in the mitral valve position due to thrombus formation. Am J Cardiol. 2013;112:1439–44.CrossRef
64.
go back to reference Korber MI, Silwedel J, Friedrichs K, et al. Bleeding complications after percutaneous mitral valve repair with the MitraClip. Am J Cardiol. 2018;121:94–9.CrossRef Korber MI, Silwedel J, Friedrichs K, et al. Bleeding complications after percutaneous mitral valve repair with the MitraClip. Am J Cardiol. 2018;121:94–9.CrossRef
65.
go back to reference Ben-Avi R, Orlov B, Sternik L, et al. Short- and long-term results after prosthetic mitral valve implantation in patients with severe mitral annulus calcification. Interact Cardiovasc Thorac Surg. 2017;24:876–81.CrossRef Ben-Avi R, Orlov B, Sternik L, et al. Short- and long-term results after prosthetic mitral valve implantation in patients with severe mitral annulus calcification. Interact Cardiovasc Thorac Surg. 2017;24:876–81.CrossRef
66.
go back to reference Guerrero M, Urena M, Himbert D, et al. 1-year outcomes of Transcatheter mitral valve replacement in patients with severe mitral annular calcification. J Am Coll Cardiol. 2018;71:1841–53.CrossRef Guerrero M, Urena M, Himbert D, et al. 1-year outcomes of Transcatheter mitral valve replacement in patients with severe mitral annular calcification. J Am Coll Cardiol. 2018;71:1841–53.CrossRef
Metadata
Title
Transcatheter Mitral Valve Therapy: Defining the Patient Who Will Benefit
Authors
Marvin H. Eng
Dee Dee Wang
Publication date
01-11-2018
Publisher
Springer US
Published in
Current Cardiology Reports / Issue 11/2018
Print ISSN: 1523-3782
Electronic ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-018-1058-8

Other articles of this Issue 11/2018

Current Cardiology Reports 11/2018 Go to the issue

Diabetes and Cardiovascular Disease (ND Wong, Section Editor)

Prevention of Heart Failure in Patients with Diabetes: Role of Diabetes Medications

Myocardial Disease (A Abbate, Section Editor)

Tumor Necrosis Factor-α in Heart Failure: an Updated Review

Echocardiography (JM Gardin and AH Waller, Section Editors)

Echocardiography in Sarcoidosis