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Current Cardiology Reports

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01-12-2017 | Cardiac PET, CT, and MRI (F Pugliese and SE Petersen, Section Editor)

Functional Information in Coronary Artery Disease: The Case of Computed Tomography Myocardial Perfusion

Authors: Klaus F. Kofoed, Mathias H. Sørgaard, Jesper J. Linde

Published in: Current Cardiology Reports | Issue 12/2017

Abstract

Purpose of Review

To review methodological and logistical aspects of CT myocardial perfusion, current clinical evidence and possible future directions, with specific focus on use in patients with coronary artery disease (CAD).

Recent Findings

CT myocardial perfusion imaging may be performed as an add-on to standard coronary CT angiography (CCTA), to identify regions of myocardial hypoperfusion, at rest and during adenosine stress. The principle of measurement is well-validated in animal experimental models, and CT myocardial perfusion imaging has a high degree of concordance with already clinically available perfusion imaging methods. Combining CCTA and CT myocardial perfusion imaging increases the diagnostic accuracy to identify patients with CAD associated with ischemia.

Summary

In patients suspected of CAD, CCTA frequently detects coronary atherosclerotic lesions, in which revascularization could be clinically beneficial. CT myocardial perfusion imaging may be helpful to identify coronary lesions associated with myocardial ischemia, and thus potentially suitable for coronary intervention.

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Title: Functional Information in Coronary Artery Disease: The Case of Computed Tomography Myocardial Perfusion
Authors: Klaus F. Kofoed
Mathias H. Sørgaard
Jesper J. Linde
Publication date: 01-12-2017
Publisher: Springer US
Published in: Current Cardiology Reports / Issue 12/2017
Print ISSN: 1523-3782
Electronic ISSN: 1534-3170
DOI: https://doi.org/10.1007/s11886-017-0937-8

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