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Published in: Current Bladder Dysfunction Reports 4/2016

01-12-2016 | Post-Prostatectomy and Acquired Voiding Dysfunction (V Tse, Section Editor)

Interstitial Cystitis/Bladder Pain Syndrome: a Review and an Update

Authors: Zhiwei Fang, Kexin Xu

Published in: Current Bladder Dysfunction Reports | Issue 4/2016

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Abstract

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic condition characterized by pelvic pain and lower urinary tract symptoms. The evolution of nomenclature of IC/BPS has experienced a long history. The disease etiology is not yet fully understood; potential pathophysiologic causes proposed include defect of layer of glycosaminoglycan (GAG) on the apical surface of bladder floor; autoimmune, inflammatory, and neurogenic mechanisms; infection; and so on. There are a lot of strategies to cure IC/BPS, mainly including behavioral therapy, oral medicines, intravesical treatments, and intradetrusor botulinum toxin A (BTXA) injection. But none of them is curative. Most treatments are aimed at controlling symptom and improving the quality of life of patients. In this article, we will talk about the new progress of definition, etiology, and treatment on IC/BPS.
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Metadata
Title
Interstitial Cystitis/Bladder Pain Syndrome: a Review and an Update
Authors
Zhiwei Fang
Kexin Xu
Publication date
01-12-2016
Publisher
Springer US
Published in
Current Bladder Dysfunction Reports / Issue 4/2016
Print ISSN: 1931-7212
Electronic ISSN: 1931-7220
DOI
https://doi.org/10.1007/s11884-016-0387-y

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