Published in:
01-12-2016 | Neurogenic Bladder (C Powell, Section Editor)
Does the Technique or Pattern Matter When Injecting OnabotulinumtoxinA?
Authors:
Michael A. Avallone, Michael L. Guralnick, R. Corey O’Connor
Published in:
Current Bladder Dysfunction Reports
|
Issue 4/2016
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Abstract
OnabotulinumtoxinA (BTX-A) is a treatment option for patients with neurogenic detrusor overactivity (NDO) or idiopathic overactive bladder (OAB) inadequately controlled with or intolerant to oral medications. The currently approved dosing is 100 U for OAB and 200 U for NDO which is commonly injected into the detrusor muscle via 20–30 trigone-sparing sites. Growing evidence suggests that the efficacy of BTX-A may be maintained with fewer injection sites, varying injection depth, and differing injection locations. This review focuses on the recent literature regarding various BTX-A injection techniques for the treatment of NDO and OAB.