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Current Atherosclerosis Reports

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01-11-2020 | Myocardial Infarction | Women and Ischemic Heart Disease (P. Kohli, Section Editor)

Gender Differences in Residual Risk Factors for Major Adverse Cardiovascular Events Following ACS and How to Bridge the Gap

Authors: Olivia Manfrini, Edina Cenko, Raffaele Bugiardini

Published in: Current Atherosclerosis Reports | Issue 11/2020

Abstract

Purpose of Review

The review aims to describe the differences between men and women in those factors that can influence a worse prognosis in women after an acute cardiovascular event.

Recent Findings

Women adequately treated with current evidence-based medications for acute myocardial infarction and for conventional cardiovascular risk factors, such as hypertension, diabetes, smoking, and dyslipidemia, still have an extra risk of death compared with men. Additional factors that increase the risk of poor prognosis for the index event have been identified.

Summary

The residual risk can be due to factors affecting the prognosis of the women from outside (they are external to the patient’s body) and also to factors that, on the contrary, belong to the female body (female being/female sex). The review will give an update on those residual risk factors, including young age, vulnerability for de novo heart failure, time from symptom onset to treatment, heath care delivered during the weekend, and depression, which generally negatively influence the outcome of women with an acute myocardial infarction.

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Title: Gender Differences in Residual Risk Factors for Major Adverse Cardiovascular Events Following ACS and How to Bridge the Gap
Authors: Olivia Manfrini
Edina Cenko
Raffaele Bugiardini
Publication date: 01-11-2020
Publisher: Springer US
Keywords: Myocardial Infarction
Acute Coronary Syndrome
Published in: Current Atherosclerosis Reports / Issue 11/2020
Print ISSN: 1523-3804
Electronic ISSN: 1534-6242
DOI: https://doi.org/10.1007/s11883-020-00882-4

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