Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
General Thoracic and Cardiovascular Surgery
Published in: General Thoracic and Cardiovascular Surgery 2/2022

01-02-2022 | Computed Tomography | Case Report

Native aortic valve thrombosis due to heparin-induced thrombocytopenia

Authors: Yu Inaba, Yasunori Iida, Hidetoshi Oka, Takahisa Miki, Takashi Hachiya, Hideyuki Shimizu

Published in: General Thoracic and Cardiovascular Surgery | Issue 2/2022

Login to get access

Abstract

A 65-year-old man with unstable angina was transferred to our department for coronary artery bypass grafting (CABG). Preoperative computed tomography indicated a large thrombosis in the left coronary cusp (LCC). CABG concomitant thrombectomy was performed under cardiopulmonary bypass using unfractionated heparin. Although the LCC was filled with a large thrombus, the left coronary artery ostium was not obstructed. The platelet count decreased by 68%, 12 days after starting heparin in the previous hospital. There is a high probability that this patient had HIT which was not recognized before surgery.
Literature
1.
Cuker A, Gimotty PA, Crowther MA, et al. Predictive value of the 4Ts scoring system for heparin-induced thrombocytopenia: a systematic review and meta-analysis. Blood. 2012;120(20):4160–7.CrossRef
2.
Vermeersch G, Prihadi E, De Keulenaer G, et al. Giant native aortic valve thrombus under non-vitamin K antagonist oral anticoagulant: first manifestation of antiphospholipid syndrome. Eur Heart J. 2020;ehaa693.
3.
Shindo S, Kubota K, Matsumoto M. Thromboembolism from the noncoronary cusp of a patient with a normal aortic valve and protein C deficiency. J Thorac Cardiovasc Surg. 2006;131(5):1171–2.CrossRef
4.
Martel N, Lee J, Wells PS. Risk for heparin-induced thrombocytopenia with unfractionated and low-molecular-weight heparin thromboprophylaxis: a meta-analysis. Blood. 2005;106(8):2710–5.CrossRef
5.
Trehel-Tursis V, Louvain-Quintard V, Zarrouki Y, Imbert A, Doubine S, Stephan F. Clinical and biologic features of patients suspected or confirmed to have heparin-induced thrombocytopenia in a cardiothoracic surgical ICU. Chest. 2012;142(4):837–44.CrossRef
Metadata
Title
Native aortic valve thrombosis due to heparin-induced thrombocytopenia
Authors
Yu Inaba
Yasunori Iida
Hidetoshi Oka
Takahisa Miki
Takashi Hachiya
Hideyuki Shimizu
Publication date
01-02-2022
Publisher
Springer Singapore
Published in
General Thoracic and Cardiovascular Surgery / Issue 2/2022
Print ISSN: 1863-6705
Electronic ISSN: 1863-6713
DOI
https://doi.org/10.1007/s11748-021-01740-z

Other articles of this Issue 2/2022

General Thoracic and Cardiovascular Surgery 2/2022 Go to the issue

Original Article

Effects of thoracic sympathetic stimulation on palmar perfusion: a preliminary study in pigs

Letter to the Editor

Does airway metallic stent limit additional treatments in patients with malignant airway stenosis?

Original Article

Effectiveness and safety of a newly introduced multidisciplinary perioperative enhanced recovery after surgery protocol for thoracic esophageal cancer surgery

Original Article

Contemporary short-term outcomes of surgery for aortic stenosis: transcatheter vs. surgical aortic valve replacement

Case Report

Transaortic approach for the repair of the basal ventricular septal rupture

Case Report

Successful excision of a giant subcarinal bronchogenic cyst by video-assisted thoracoscopic surgery