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Internal and Emergency Medicine
Published in: Internal and Emergency Medicine 6/2019

01-09-2019 | Septicemia | THE CUTTING EDGE: RESEARCH UPDATE

Targeting peripheral perfusion versus serum lactate levels in septic shock

Authors: Marianna Porzio, Guido Baldini, Cristiana Di Maggio, Gruppo di Autoformazione Metodologica (GrAM)

Published in: Internal and Emergency Medicine | Issue 6/2019

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Excerpt

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection [1‐2]. Sepsis and septic shock are major healthcare problems, affecting millions of people around the world each year, and killing as many as one in four [3]. …
Literature
1.
Singer M, Deutschman CS, Seymour CW et al (2016) The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA 315(8):801–810CrossRefPubMedPubMedCentral
2.
Rusconi AM, Bossi I, Lampard JG et al (2015) Early goal-directed therapy vs usual care in the treatment of severe sepsis and septic shock: a systematic review and meta-analysis. Intern Emerg Med 10(6):731–743CrossRefPubMed
3.
Martin GS, Mannino DM, Eaton S, Moss M (2003) The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 348(16):1546–1554CrossRefPubMed
4.
Levy MM, Evans LE, Rhodes A (2018) The surviving sepsis campaign bundle: 2018 update. Crit Care Med 46(6):997–1000CrossRefPubMed
5.
Hernández G, Ospina-Tascón GA GAANDROMEDA-SHOCK Investigators and the Latin America Intensive Care Network (LIVEN) (2019) Effect of a resuscitation strategy targeting peripheral perfusion status vs serum lactate levels on 28-day mortality among patients with septic shock: the ANDROMEDA-SHOCK randomized clinical trial. JAMA 321(7):654–664CrossRefPubMedPubMedCentral
Metadata
Title
Targeting peripheral perfusion versus serum lactate levels in septic shock
Authors
Marianna Porzio
Guido Baldini
Cristiana Di Maggio
Gruppo di Autoformazione Metodologica (GrAM)
Publication date
01-09-2019
Publisher
Springer International Publishing
Published in
Internal and Emergency Medicine / Issue 6/2019
Print ISSN: 1828-0447
Electronic ISSN: 1970-9366
DOI
https://doi.org/10.1007/s11739-019-02152-x

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