Published in:
01-05-2019 | Endoscopy | Original Contributions
Systematic Endoscopy 5 Years After Sleeve Gastrectomy Results in a High Rate of Barrett’s Esophagus: Results of a Multicenter Study
Authors:
Lionel Sebastianelli, Marine Benois, Geoffroy Vanbiervliet, Laurent Bailly, Maud Robert, Nicolas Turrin, Emmanuel Gizard, Mirto Foletto, Marco Bisello, Alice Albanese, Antonella Santonicola, Paola Iovino, Thierry Piche, Luigi Angrisani, Laurent Turchi, Luigi Schiavo, Antonio Iannelli
Published in:
Obesity Surgery
|
Issue 5/2019
Login to get access
Abstract
Background
Recent evidence has indicated an increased risk of Barrett’s esophagus (BE) in the long term after sleeve gastrectomy (SG).
Aim
The aim of the study is to investigate the spectrum of gastroesophageal reflux disease (GERD) symptoms as well as the prevalence of BE, at minimum 5 years after SG in patients who underwent SG in different bariatric centers of two countries: France and Italy.
Patients and Methods
Five high volume outpatient centers dedicated to bariatric surgery that routinely perform upper GI endoscopy before any bariatric procedures were invited to participate in the study. From January 2017 to June 2018, each center during scheduled postoperative evaluation after surgery asked a minimum 10 consecutive patients, which had performed SG at least 5 years before and with no evidence of BE preoperatively, to undergo another upper GI endoscopy.
Results
Ninety (66 F) consecutive patients were enrolled. The mean follow-up was 78 ± 15 months, and the mean total body weight loss was 25 ± 12%. The prevalence of BE was 18.8% with no significant difference among centers. Weight loss failure was significantly associated with BE (p < 0.01). The prevalence of GERD symptoms, erosive esophagitis, and the usage of PPIs increased from 22%, 10%, and 22% before the SG to 76%, 41%, and 52% at the time of follow-up, respectively (p < 0.05).
Conclusions
This multicenter study show a high rate of BE at least 5 years after SG. Weight loss failure was significantly associated with BE. We suggest to provide systematic endoscopy in these patients to rule out this condition.