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Open Access 01-12-2021 | Original Article

Epidemiology of hip fracture in Botswana

Authors: M. Kebaetse, S. Nkhwa, M. Mogodi, J. Masunge, Y. P. Gureja, M. Ramabu, T. Mmopelwa, I. Sharif, A. Orford, H. Johansson, N. C. Harvey, E. V. McCloskey, J. A. Cauley, J. A. Kanis

Published in: Archives of Osteoporosis | Issue 1/2021

Abstract

Summary

A retrospective population-based survey in the Republic of Botswana determined the incidence of fractures at the hip over 3 years. The estimated number of such fractures nationwide for 2020 was 103 and is predicted to increase.

Objective

This article describes the epidemiology of hip fractures in the Republic of Botswana.

Methods

A retrospective patient chart review was conducted to identify from hospital registers the number of patients diagnosed with hip fracture in 2009, 2010, and 2011. Age- and sex-specific incidence of hip fracture was determined from which lifetime probabilities and future projections for hip fracture were calculated.

Results

The incidence of hip fracture was low and comparable to rates reported from Tunisia. The remaining lifetime risk of hip fracture at the age of 50 years in men and women was 1.4 and 1.1%, respectively. The incidence of hip fracture suggested that the estimated number of hip fractures nationwide in persons over the age of 50 years for 2020 was 103 and is predicted to increase by more than threefold to 372 in 2050.

Conclusion

The hip fracture rates can be used for healthcare planning. Additionally, these data can be used to create a FRAX model to help guide decisions about treatment.

Jervas E, Onwukamuche CK, Anyanwu GE, Ugochukwu AI (2011) Incidence of fall related hip fractures among the elderly persons in Owerri, Nigeria. Asian J Med Sci 3:110–114

Zebaze RM, Seeman E (2003) Epidemiology of hip and wrist fractures in Cameroon, Africa. Osteoporos Int 14:301–305CrossRef

Adebajo AO, Cooper C, Evans JG (1991) Fractures of the hip and distal forearm in West Africa and the United Kingdom. Age Ageing 20:435–438CrossRef

Solomon L (1968) Osteoporosis and fracture of the femoral neck in the South African Bantu. J Bone Joint Surg 50:1–13CrossRef

Paruk F, Matthews G, Cassim B (2017) Osteoporotic hip fractures in Black South Africans: a regional study. Arch Osteoporos 12:107CrossRef

Dela SS, Paruk F, Brown SL, Lukhele M, Kalla AA, Jordaan JD, Conradie M, Mohamed O, Chutterpaul P, Cassim B (2020) Ethnic and gender-specific incidence rates for hip fractures in South Africa: a multi-centre study [published correction appears in Bone. 2020 Aug;137:115435]. Bone. 115253:133

Cauley JA, El-Hajj Fuleihan G, Arabi A, Fujiwara S, Ragi-Eis S, Calderon A, Chionh SB, Chen Z, Curtis JR, Danielson ME, Hanley DA, Kroger H, Kung AW, Lesnyak O, Nieves J, Pluskiewicz W, El Rassi R, Silverman S, Schott AM, Rizzoli R, Luckey M, FRAX® Position Conference Members (2011) Official Positions for FRAX® clinical regarding international differences from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX®. J Clin Densitom 14:240–262CrossRef

Cummings SR, Melton LJ (2002) Epidemiology and outcomes of osteoporotic fractures. Lancet 359:1761–1767CrossRef

Central Intelligence Agency (2020) The World Factbook. https://www.cia.gov/library/publications/the-world-factbook/geos/bc.html. accessed 1st September 2020

10.

Mackey DC, Lui LY, Cawthon PM, Bauer DC, Nevitt MC, Cauley JA, Hillier TA, Lewis CE, Barrett-Connor E, Cummings SR, Study of Osteoporotic Fractures (SOF) and Osteoporotic Fractures in Men Study (MrOS) Research Groups (2007) High-trauma fractures and low bone mineral density in older women and men. JAMA. 298(20):2381–2388CrossRef

11.

Sanders KM, Pasco JA, Ugoni AM, Nicholson GC, Seeman E, Martin TJ, Skoric B, Panahi S, Kotowicz MA (1998) The exclusion of high trauma fractures may underestimate the prevalence of bone fragility fractures in the community: the Geelong Osteoporosis Study. J Bone Miner Res 13(8):1337–1342CrossRef

12.

Leslie WD, Schousboe JT, Morin SN, Martineau P, Lix JM, Johansson H, McCloskey EV, Harvey NC, Kanis JA (2020) Fracture risk following high-trauma versus non-trauma fracture: a registry-based cohort study. Osteoporos Int 31:1059–1067CrossRef

13.

Statistics Botswana (2014) Population & Housing Census 2011. http://www.statsbots.org.bw/sites/default/files/publications/Population%20and%20Housing%20Census%202011%20%20Dissemination%20seminar%20report.pdf Accessed 4 August 2020

14.

United Nations. Department of Economic and Social Affairs. Population Division (2017). World Population Prospects: The 2017 Revision. DVD Edition

15.

Zakroyeva A, Lesnyak O, Cazac V, Groppa L, Russu E, Chislari L, Rotaru L, Johansson H, Harvey NC, McCloskey E, Kanis JA (2020) Epidemiology of osteoporotic fracture in Moldova and development of a country specific FRAX model. Arch Osteoporos 15:13. https://doi.org/10.1007/s11657-019-0669-zCrossRefPubMedPubMedCentral

16.

Kanis JA, Oden A, Johnell O, Jonsson B, de Laet C, Dawson A (2001) The burden of osteoporotic fractures: a method for setting intervention thresholds. Osteoporos Int 12:417–427CrossRef

17.

Siggeirsdottir K, Aspelund T, Johansson H, Gudmundsson EF, Mogensen B, Jonsson BY, Gudnason V, McCloskey E, Oden A, Sigurdsson G, Kanis JA (2014) The incidence of a first major osteoporotic fracture in Iceland and implications for FRAX. Osteoporos Int 25:2445–2451CrossRef

18.

Lam A, Leslie WD, Lix LM, Yogendran M, Morin SN, Majumdar SR (2014) Major osteoporotic to hip fracture ratios in Canadian men and women with Swedish comparisons: a population-based analysis. J Bone Miner Res 29:1067–1073CrossRef

19.

Kanis JA, Johnell O, De Laet C, Jonsson B, Oden A, Ogelsby AK (2002) International variations in hip fracture probabilities: implications for risk assessment. J Bone Miner Res 17:1237–1244CrossRef

20.

Kanis JA, Odén A, McCloskey EV, Johansson H, Wahl D, Cyrus Cooper C, on behalf of the IOF Working Group on Epidemiology and Quality of Life (2012) A systematic review of hip fracture incidence and probability of fracture worldwide. Osteoporos Int 23:2239–2256CrossRef

21.

Lesnyak O, Ismailov S, Shakirova M, Alikhanova NA, Zakroyeva A, Johansson H, Harvey NC, McCloskey E, Kanis JA (2020) Epidemiology of hip fracture and the development of a FRAX model for Uzbekistan. Arch Osteoporos 15(1):119. https://doi.org/10.1007/s11657-020-00792-7CrossRefPubMedPubMedCentral

22.

Elffors L, Allander E, Kanis JA, Gullberg B, Johnell O, Dequeker J, Dilzen G, Gennari C, Lopez-Vaz AA, Lyritis G, Mazzuoli GF, Miravet L, Passeri M, Perez Cano R, Rapado A, Ribot C (1994) The variable incidence of hip fracture in Southern Europe. The MEDOS Study. Osteoporos Int 4:253–263CrossRef

23.

Statistics South Africa (2015) Census 2011: estimation of mortality in South Africa. Report No. 03-01-62. http://www.statssa.gov.za/publications/Report-03-01-62/Report-03-01-622011.pdf. Accessed 2 May 2020

24.

Cooper C, Cole ZA, Holroyd CR, Earl SC, Harvey NC, Dennison EM, Melton LJ, Cummings SR, Kanis JA, the IOF CSA Working Group on Fracture Epidemiology (2011) Secular trends in the incidence of hip and other osteoporotic fractures. Osteoporos Int 22:1277–1288CrossRef

25.

Gullberg B, Johnell O, Kanis JA (1997) World-wide projections for hip fracture. Osteoporos Int 7:407–413CrossRef

26.

Lesnyak O, Ershova O, Belova K, Gladkova E, Sinitsina O, Ganert O, Romanova M, Khodirev V, Johansson H, McCloskey E, Kanis JA (2012) Epidemiology of fracture in the Russian Federation and the development of a FRAX model. Arch Osteoporos 7:67–73. https://doi.org/10.1007/s11657-012-0082-3CrossRefPubMed

27.

Lesnyak O, Sahakyan S, Zakroyeva A, Bilezikian JP, Hutchings N, Galstyan R, Lebedev A, Johansson H, Harvey NC, McCloskey E, Kanis JA (2017) Epidemiology of fractures in Armenia: development of a country-specific FRAX model and comparison to its surrogate. Arch Osteoporos 12(1):98. https://doi.org/10.1007/s11657-017-0392-6CrossRefPubMedPubMedCentral

28.

Ramanau H, Chernyanin I, Rudenka E, Lesnyak O, Zakroyeva A, Bilezikian JP, Johansson H, Harvey NC, McCloskey EV, Kanis JA (2018) Epidemiology of hip fracture in Belarus: development of a country-specific FRAX model and its comparison to neighbouring country models. Arch Osteoporos 13:42. https://doi.org/10.1007/s11657-018-0454-4CrossRefPubMedPubMedCentral

29.

Issayeva S, Lesnyak O, Zakroyeva A, Issayeva B, Dilmanova D, Johansson H, Harvey NC, McCloskey E, Kanis JA (2020) Epidemiology of osteoporotic fractures in the Republic of Kazakhstan and the development of country specific FRAX model. Arch Osteoporos 15(1):30. https://doi.org/10.1007/s11657-020-0701-3CrossRefPubMedPubMedCentral

Title: Epidemiology of hip fracture in Botswana
Authors: M. Kebaetse
S. Nkhwa
M. Mogodi
J. Masunge
Y. P. Gureja
M. Ramabu
T. Mmopelwa
I. Sharif
A. Orford
H. Johansson
N. C. Harvey
E. V. McCloskey
J. A. Cauley
J. A. Kanis
Publication date: 01-12-2021
Publisher: Springer London
Published in: Archives of Osteoporosis / Issue 1/2021
Print ISSN: 1862-3522
Electronic ISSN: 1862-3514
DOI: https://doi.org/10.1007/s11657-021-00885-x

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Epidemiology of hip fracture in Botswana

Abstract

Summary

Objective

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Summary

Objective

Methods

Results

Conclusion

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