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Published in: Journal of General Internal Medicine 12/2020

01-12-2020 | COVID-19 | Original Research

Comparing Associations of State Reopening Strategies with COVID-19 Burden

Authors: Brystana G. Kaufman, PhD, Rebecca Whitaker, PhD, Nirosha Mahendraratnam, PhD, Valerie A. Smith, DrPH, Mark B. McClellan, MD, PhD

Published in: Journal of General Internal Medicine | Issue 12/2020

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Abstract

Background

The novel coronavirus disease 2019 (COVID-19) infected over 5 million United States (US) residents resulting in more than 180,000 deaths by August 2020. To mitigate transmission, most states ordered shelter-in-place orders in March and reopening strategies varied.

Objective

To estimate excess COVID-19 cases and deaths after reopening compared with trends prior to reopening for two groups of states: (1) states with an evidence-based reopening strategy, defined as reopening indoor dining after implementing a statewide mask mandate, and (2) states reopening indoor dining rooms before implementing a statewide mask mandate.

Design

Interrupted time series quasi-experimental study design applied to publicly available secondary data.

Participants

Fifty United States and the District of Columbia.

Interventions

Reopening indoor dining rooms before or after implementing a statewide mask mandate.

Main Measures

Outcomes included daily cumulative COVID-19 cases and deaths for each state.

Key Results

On average, the number of excess cases per 100,000 residents in states reopening without masks is ten times the number in states reopening with masks after 8 weeks (643.1 cases; 95% confidence interval (CI) = 406.9, 879.2 and 62.9 cases; CI = 12.6, 113.1, respectively). Excess cases after 6 weeks could have been reduced by 90% from 576,371 to 63,062 and excess deaths reduced by 80% from 22,851 to 4858 had states implemented mask mandates prior to reopening. Over 50,000 excess deaths were prevented within 6 weeks in 13 states that implemented mask mandates prior to reopening.

Conclusions

Additional mitigation measures such as mask use counteract the potential growth in COVID-19 cases and deaths due to reopening businesses. This study contributes to the growing evidence that mask usage is essential for mitigating community transmission of COVID-19. States should delay further reopening until mask mandates are fully implemented, and enforcement by local businesses will be critical for preventing potential future closures.
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Literature
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go back to reference Fisher KA. IVY Network Investigators, CDC COVID-19 Response Team. Community and Close Contact Exposures Associated with COVID-19 Among Symptomatic Adults ≥18 Years in 11 Outpatient Health Care Facilities — United States, July 2020. Morbidity and Mortality Weekly Report. 2020;69(36):6. Fisher KA. IVY Network Investigators, CDC COVID-19 Response Team. Community and Close Contact Exposures Associated with COVID-19 Among Symptomatic Adults ≥18 Years in 11 Outpatient Health Care Facilities — United States, July 2020. Morbidity and Mortality Weekly Report. 2020;69(36):6.
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go back to reference Kaufman BG, Whitaker R, Lederer NM, et al. State Variation in Effects of Non-Essential Business and Public School Closure on COVID-19 Cases. Pre-Publication. 2020. Kaufman BG, Whitaker R, Lederer NM, et al. State Variation in Effects of Non-Essential Business and Public School Closure on COVID-19 Cases. Pre-Publication. 2020.
Metadata
Title
Comparing Associations of State Reopening Strategies with COVID-19 Burden
Authors
Brystana G. Kaufman, PhD
Rebecca Whitaker, PhD
Nirosha Mahendraratnam, PhD
Valerie A. Smith, DrPH
Mark B. McClellan, MD, PhD
Publication date
01-12-2020
Publisher
Springer International Publishing
Keyword
COVID-19
Published in
Journal of General Internal Medicine / Issue 12/2020
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-020-06277-0

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