Top

Published in:

01-10-2020 | Acute Kidney Injury | Clinical Vignette

COVID-19 and Rhabdomyolysis

Authors: Nicholas R. Chedid, M.D., Swalpa Udit, M.D., PhD., Zhabiz Solhjou, M.D., Maria Y. Patanwala, M.D., Alice M. Sheridan, M.D., Ebrahim Barkoudah, M.D., M.P.H.

Published in: Journal of General Internal Medicine | Issue 10/2020

Excerpt

The ongoing pandemic of COVID-19 has become a focus of global research as many characteristics of this virus are still being defined.¹ The most common symptoms currently associated with COVID-19 include fever, cough, and fatigue.² Rhabdomyolysis is rarely seen and was only reported in 0.2% of patients in a study of 1099 patients in China.² …

World Health Organization. Coronavirus disease 2019 (COVID-19): situation report, 59. https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200319-sitrep-59-covid-19.pdf?sfvrsn=c3dcdef9_2 accessed on 31 May, 2020

Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, Liu L, Shan H, Lei CL, Hui DS, Du B. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020.

Huerta-Alardín AL, Varon J, Marik PE. Bench-to-bedside review: Rhabdomyolysis–an overview for clinicians. Crit Care. 2004;9(2):158.CrossRef

Melli G, Chaudhry V, Cornblath DR. Rhabdomyolysis: an evaluation of 475 hospitalized patients. Medicine. 2005;84(6):377-85.CrossRef

McMahon GM, Zeng X, Waikar SS. A risk prediction score for kidney failure or mortality in rhabdomyolysis. JAMA Intern Med. 2013;173(19):1821-7.CrossRef

Cabeça TK, Bellei N. Human coronavirus NL-63 infection in a Brazilian patient suspected of H1N1 2009 influenza infection: description of a fatal case. J Clin Virol. 2012;53(1):82-4.CrossRef

Chen LL, Hsu CW, Tian YC, et al. Rhabdomyolysis associated with acute renal failure in patients with severe acute respiratory syndrome. Int J Clin Pract. 2005;59(10):1162-6.CrossRef

Jin M, Tong Q. Rhabdomyolysis as Potential Late Complication Associated with COVID-19. Emerg Infect Dis. 2020;26(7).

Westermann D, Neumann JT, Sörensen NA, Blankenberg S. High-sensitivity assays for troponin in patients with cardiac disease. Nat Rev Cardiol. 2017;14(8):472.CrossRef

10.

Ron D, Taitelman U, Michaelson M, Bar-Joseph G, Bursztein S, Better OS. Prevention of acute renal failure in traumatic rhabdomyolysis. Arch Intern Med. 1984;144(2):277-80.CrossRef

11.

World Health Organization. Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected: Interim guidance V 1.2. https://www.who.int/publications-detail/clinical-management-of-severe-acute-respiratory-infection-when-novel-coronavirus-(ncov)-infection-is-suspected accessed on 9 April, 2020.

12.

Sise ME, Baggett MV, Shepard JO, Stevens JS, Rhee EP. Case 17-2020: A 68-Year-Old Man with Covid-19 and Acute Kidney Injury. N Engl J Med. 2020; doi:https://doi.org/10.1056/NEJMcpc2002418.

13.

Lippi G, Lavie CJ, Sanchis-Gomar F. Cardiac troponin I in patients with coronavirus disease 2019 (COVID-19): Evidence from a meta-analysis. Prog Cardiovasc Dis. 2020.

14.

Clerkin KJ, Fried JA, Raikhelkar J, Sayer G, Griffin JM, Masoumi A, Jain SS, Burkhoff D, Kumaraiah D, Rabbani L, Schwartz A, Uriel N. Coronavirus Disease 2019 (COVID-19) and Cardiovascular Disease. 2020.

15.

Lai CC, Shih TP, Ko WC, Tang HJ, Hsueh PR. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and corona virus disease-2019 (COVID-19): the epidemic and the challenges. Int J Antimicrob Agents. 2020:105924.

16.

Cheng Y, Luo R, Wang K, Zhang M, Wang Z, Dong L, Li J, Yao Y, Ge S, Xu G. Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney Int. 2020.

17.

Fan C, Li K, Ding Y, Lu WL, Wang J. ACE2 expression in kidney and testis may cause kidney and testis damage after 2019-nCoV infection. medRxiv. 2020.

18.

Puelles VG, Lütgehetmann M, Lindenmeyer MT, Sperhake JP, Wong MN, Allweiss L, Chilla S, Heinemann A, Wanner N, Liu S, Braun F, Lu S, Pfefferle S, Schröder AS, Edler C, Gross O, Glatzel M, Wichmann D, Wiech T, Kluge S, Pueschel K, Aepfelbacher M, Huber TB. Multiorgan and Renal Tropism of SARS-CoV-2. N Engl J Med. 2020; doi:https://doi.org/10.1056/NEJMc2011400.

19.

Wang W, Xu Y, Gao R, Lu R, Han K, Wu G, Tan W. Detection of SARS-CoV-2 in different types of clinical specimens. JAMA. 2020.

20.

Peng L, Liu J, Xu W, Luo Q, Deng K, Lin B, Gao Z. 2019 Novel Coronavirus can be detected in urine, blood, anal swabs and oropharyngeal swabs samples. medRxiv. 2020.

21.

To KKW, Tsang OTY, Leung WS, Tam AR, Wu TC, Lung DC, Yip CCY, Cai JP, Chan JMC, Chik TSH, Lau DPL. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis. 2020.

22.

Hu H, Ma F, Wei X, Fang Y. Coronavirus fulminant myocarditis saved with glucocorticoid and human immunoglobulin. Eur Heart J. 2020.

23.

Inciardi RM, Lupi L, Zaccone G, Italia L, Raffo M, Tomasoni D, Cani DS, Cerini M, Farina D, Gavazzi E, Maroldi R. Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19). JAMA Cardiol. 2020.

24.

Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, Zhang L, Fan G, Xu J, Gu X, Cheng Z. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-506.CrossRef

Title: COVID-19 and Rhabdomyolysis
Authors: Nicholas R. Chedid, M.D.
Swalpa Udit, M.D., PhD.
Zhabiz Solhjou, M.D.
Maria Y. Patanwala, M.D.
Alice M. Sheridan, M.D.
Ebrahim Barkoudah, M.D., M.P.H.
Publication date: 01-10-2020
Publisher: Springer International Publishing
Keywords: Acute Kidney Injury
Myalgie
Myalgia
SARS-CoV-2
COVID-19
Acute Kidney Injury
Published in: Journal of General Internal Medicine / Issue 10/2020
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI: https://doi.org/10.1007/s11606-020-06039-y

ACC 2024 Congress Coverage

Heart Failure Video

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

COVID-19 and Rhabdomyolysis

Excerpt

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

» View more highlights on the ACC 2024 congress hub page

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 10/2020

Characterization of Patients Who Return to Hospital Following Discharge from Hospitalization for COVID-19

Impact of Instrumental Activities of Daily Living Limitations on Hospital Readmission: an Observational Study Using Machine Learning

Sexual Harassment of Female Providers by Patients: a Qualitative Study

A Model for Rapid Transition to Virtual Care, VA Connecticut Primary Care Response to COVID-19

Dealing with the Lack of Time for Detailed Shared Decision-making in Primary Care: Everyday Shared Decision-making

Racial and Ethnic Disparities in Population-Level Covid-19 Mortality

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

» View more highlights on the ACC 2024 congress hub page