Published in:
01-07-2020 | Care | Original Research
Instability in End-of-Life Care Preference Among Heart Failure Patients: Secondary Analysis of a Randomized Controlled Trial in Singapore
Published in: Journal of General Internal Medicine | Issue 7/2020
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Background
Efforts to improve quality of end-of-life (EOL) care are increasingly focused on eliciting patients’ EOL preference through advance care planning (ACP). However, if patients’ EOL preference changes over time and their ACP documents are not updated, these documents may no longer be valid at the time EOL decisions are made.
Objectives
To assess extent and correlates of changes in stated preference for aggressive EOL care over time.
Design
Secondary analysis of data from a randomized controlled trial of a formal ACP program versus usual care in Singapore.
Patients
Two hundred eighty-two patients with heart failure (HF) and New York Heart Association Classification III and IV symptoms were recruited and interviewed every 4 months for up to 2 years to assess their preference for EOL care. Analytic sample included 200 patients interviewed at least twice.
Results
Nearly two thirds (64%) of patients changed their preferred type of EOL care at least once. Proportion of patients changing their stated preference for type of EOL care increased with time and the change was not unidirectional. Patients who understood their prognosis correctly were less likely to change their preference from non-aggressive to aggressive EOL care (OR 0.66, p value 0.07) or to prefer aggressive EOL care (OR 0.53; p value 0.001). On the other hand, patient-surrogate discussion of care preference was associated with a higher likelihood of change in patient preference from aggressive to non-aggressive EOL care (OR 1.83; p value 0.03).
Conclusion
The study provides evidence of instability in HF patients’ stated EOL care preference. This undermines the value of an ACP document recorded months before EOL decisions are made unless a strategy exists for easily updating this preference.
Trial Registration
ClinicalTrials.gov: NCT02299180