Published in:
01-04-2020 | Stevens-Johnson Syndrome | Clinical Image
A Young Man with Red Eyes, Polymorphous Rash, and Mucositis—an On-the-Spot Diagnosis
Published in: Journal of General Internal Medicine | Issue 4/2020
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A previously healthy 18-year-old man presented with malaise, fever, and rash for 5 days. His only recent medication was amoxicillin for otitis media 2 weeks before symptom onset. Examination revealed conjunctival hyperemia, polymorphous rash, and labial, oral, and nasal mucositis (Figs. 1 and 2). Laboratory testing and a chest radiograph were unremarkable. Bacterial blood cultures, HIV testing, Mycoplasma pneumonia testing, and PCR for herpes simplex virus were negative. He was diagnosed with Stevens-Johnson syndrome (SJS) due to amoxicillin and his symptoms resolved after 3 weeks.
Fig. 1
Polymorphous skin rash and mucositis of the lips. The skin lesions included non-pruritic erythematous lesions, erupted vesicles in chest, targetoid lesions in palms, and areas of denuded skin in ears. The minimal suction generated by the EKG suction electrodes on the skin of shoulders caused erythematous lesions
Fig. 2
Feet and mouth manifestations. Targetoid lesions with darker center in foot. Severe mucositis of the lips and the buccal mucosa
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