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Published in: Journal of General Internal Medicine 1/2020

01-01-2020 | Care | Original Research

How Clinicians Discuss Medications During Primary Care Encounters Among Older Adults with Cognitive Impairment

Authors: Ariel R. Green, MD, MPH, PhD, Jennifer L. Wolff, PhD, Diane M. Echavarria, MS, Malcolm Chapman, BA, Annie Phung, MS, Devon Smith, BA, Cynthia M. Boyd, MD, MPH

Published in: Journal of General Internal Medicine | Issue 1/2020

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Abstract

Background

People with cognitive impairment experience high rates of polypharmacy and potentially inappropriate medication use. How clinicians communicate about medications may affect to what extent patients and family companions understand and participate in decisions about medication use.

Objective

To characterize how primary care clinicians discuss medications during encounters with older adults with cognitive impairment and their companions.

Design

Qualitative content analysis of audio-recorded clinical encounters from SAME Page, a randomized controlled trial to examine the effects of a patient-family agenda setting checklist on primary care visit communication among patients with cognitive impairment. Visits occurred between August 2016 and August 2017.

Participants

Patients were 65 or older, had > 1 incorrect answer on a cognitive screener, and attended visits with a relative or unpaid companion. Clinicians were physicians, nurse practitioners, or physician assistants at participating practices.

Approach

The encounters were transcribed verbatim. We used qualitative content analysis to identify major themes.

Key Results

Patients were on average 79.9 years of age. The average MMSE score was 21.6. About half of clinicians reported practicing for 15 or more years (n = 8). We identified three major themes. First, we found numerous instances in which primary care clinicians introduced patients and companions to key principles of optimal prescribing and deprescribing. Second, clinicians used a variety of approaches to foster shared decision-making about medication use. Third, several challenges prevented clinicians from working together with patients and companions to optimize prescribing and deprescribing.

Conclusions

This study offers insight into key language clinicians can use to initiate discussions about optimizing prescribing, as well as barriers they face in doing so. Examples identified in these transcripts should be tested with patients and caregivers to examine how such communications are received and interpreted. Future research should develop and test interventions that seek to overcome obstacles to optimizing prescribing for older adults with cognitive impairment.
Appendix
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Literature
1.
go back to reference Alzheimer's Association. 2015 Alzheimer’s disease facts and figures. Alzheimers Dement. 2015;11(3):332-384. Alzheimer's Association. 2015 Alzheimer’s disease facts and figures. Alzheimers Dement. 2015;11(3):332-384.
2.
go back to reference Plassman BL, Langa KM, Fisher GG, et al. Prevalence of cognitive impairment without dementia in the United States. Ann Intern Med. 2008;148(6):427-434.PubMedPubMedCentral Plassman BL, Langa KM, Fisher GG, et al. Prevalence of cognitive impairment without dementia in the United States. Ann Intern Med. 2008;148(6):427-434.PubMedPubMedCentral
3.
go back to reference Alzheimer's Association. 2018 Alzheimer’s disease facts and figures. Alzheimers Dement. 2018;14(3):367-429. Alzheimer's Association. 2018 Alzheimer’s disease facts and figures. Alzheimers Dement. 2018;14(3):367-429.
4.
go back to reference Lyketsos CG. Neuropsychiatric Symptoms in Dementia: Overview and Measurement Challenges. J Prev Alzheimers Dis. 2015;2(3):155-156.PubMedPubMedCentral Lyketsos CG. Neuropsychiatric Symptoms in Dementia: Overview and Measurement Challenges. J Prev Alzheimers Dis. 2015;2(3):155-156.PubMedPubMedCentral
5.
go back to reference Elmstahl S, Stenberg I, Annerstedt L, Ingvad B. Behavioral disturbances and pharmacological treatment of patients with dementia in family caregiving: a 2-year follow-up. Int Psychogeriatr. 1998;10(3):239-252.PubMed Elmstahl S, Stenberg I, Annerstedt L, Ingvad B. Behavioral disturbances and pharmacological treatment of patients with dementia in family caregiving: a 2-year follow-up. Int Psychogeriatr. 1998;10(3):239-252.PubMed
6.
go back to reference Lau DT, Mercaldo ND, Harris AT, Trittschuh E, Shega J, Weintraub S. Polypharmacy and potentially inappropriate medication use among community-dwelling elders with dementia. Alzheimer Dis Assoc Disord. 2010;24(1):56-63.PubMedPubMedCentral Lau DT, Mercaldo ND, Harris AT, Trittschuh E, Shega J, Weintraub S. Polypharmacy and potentially inappropriate medication use among community-dwelling elders with dementia. Alzheimer Dis Assoc Disord. 2010;24(1):56-63.PubMedPubMedCentral
7.
go back to reference Johnell K. Inappropriate Drug Use in People with Cognitive Impairment and Dementia: A Systematic Review. Curr Clin Pharmacol. 2015;10(3):178-184.PubMedPubMedCentral Johnell K. Inappropriate Drug Use in People with Cognitive Impairment and Dementia: A Systematic Review. Curr Clin Pharmacol. 2015;10(3):178-184.PubMedPubMedCentral
8.
go back to reference Castelino RL, Hilmer SN, Bajorek BV, Nishtala P, Chen TF. Drug Burden Index and potentially inappropriate medications in community-dwelling older people: the impact of Home Medicines Review. Drugs Aging. 2010;27(2):135-148.PubMed Castelino RL, Hilmer SN, Bajorek BV, Nishtala P, Chen TF. Drug Burden Index and potentially inappropriate medications in community-dwelling older people: the impact of Home Medicines Review. Drugs Aging. 2010;27(2):135-148.PubMed
9.
go back to reference Lin PJ, Fillit HM, Cohen JT, Neumann PJ. Potentially avoidable hospitalizations among Medicare beneficiaries with Alzheimer’s disease and related disorders. Alzheimers Dement. 2013;9(1):30-38.PubMed Lin PJ, Fillit HM, Cohen JT, Neumann PJ. Potentially avoidable hospitalizations among Medicare beneficiaries with Alzheimer’s disease and related disorders. Alzheimers Dement. 2013;9(1):30-38.PubMed
10.
go back to reference Patel A, Parikh R, Howell EH, Hsich E, Landers SH, Gorodeski EZ. Mini-cog performance: novel marker of post discharge risk among patients hospitalized for heart failure. Circ Heart Fail. 2015;8(1):8-16.PubMed Patel A, Parikh R, Howell EH, Hsich E, Landers SH, Gorodeski EZ. Mini-cog performance: novel marker of post discharge risk among patients hospitalized for heart failure. Circ Heart Fail. 2015;8(1):8-16.PubMed
11.
go back to reference Carnahan RM, Lund BC, Perry PJ, Chrischilles EA. The concurrent use of anticholinergics and cholinesterase inhibitors: rare event or common practice? J Am Geriatr Soc. 2004;52(12):2082-2087.PubMed Carnahan RM, Lund BC, Perry PJ, Chrischilles EA. The concurrent use of anticholinergics and cholinesterase inhibitors: rare event or common practice? J Am Geriatr Soc. 2004;52(12):2082-2087.PubMed
12.
go back to reference Moga DC, Carnahan RM, Lund BC, et al. Risks and benefits of bladder antimuscarinics among elderly residents of Veterans Affairs Community Living Centers. J Am Med Dir Assoc. 2013;14(10):749-760.PubMed Moga DC, Carnahan RM, Lund BC, et al. Risks and benefits of bladder antimuscarinics among elderly residents of Veterans Affairs Community Living Centers. J Am Med Dir Assoc. 2013;14(10):749-760.PubMed
13.
go back to reference Berdot S, Bertrand M, Dartigues JF, et al. Inappropriate medication use and risk of falls--a prospective study in a large community-dwelling elderly cohort. BMC Geriatr. 2009;9:30.PubMedPubMedCentral Berdot S, Bertrand M, Dartigues JF, et al. Inappropriate medication use and risk of falls--a prospective study in a large community-dwelling elderly cohort. BMC Geriatr. 2009;9:30.PubMedPubMedCentral
14.
go back to reference Kay GG, Abou-Donia MB, Messer WS, Jr., Murphy DG, Tsao JW, Ouslander JG. Antimuscarinic drugs for overactive bladder and their potential effects on cognitive function in older patients. J Am Geriatr Soc. 2005;53(12):2195-2201.PubMed Kay GG, Abou-Donia MB, Messer WS, Jr., Murphy DG, Tsao JW, Ouslander JG. Antimuscarinic drugs for overactive bladder and their potential effects on cognitive function in older patients. J Am Geriatr Soc. 2005;53(12):2195-2201.PubMed
15.
go back to reference Campbell N, Boustani M, Limbil T, et al. The cognitive impact of anticholinergics: a clinical review. Clin Interv Aging. 2009;4:225-233.PubMedPubMedCentral Campbell N, Boustani M, Limbil T, et al. The cognitive impact of anticholinergics: a clinical review. Clin Interv Aging. 2009;4:225-233.PubMedPubMedCentral
16.
go back to reference Sunderland T, Esposito G, Molchan SE, et al. Differential cholinergic regulation in Alzheimer’s patients compared to controls following chronic blockade with scopolamine: a SPECT study. Psychopharmacology. 1995;121(2):231-241.PubMed Sunderland T, Esposito G, Molchan SE, et al. Differential cholinergic regulation in Alzheimer’s patients compared to controls following chronic blockade with scopolamine: a SPECT study. Psychopharmacology. 1995;121(2):231-241.PubMed
17.
go back to reference Gray SL, Anderson ML, Dublin S, et al. Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study. JAMA Intern Med. 2015;175(3):401-407.PubMedPubMedCentral Gray SL, Anderson ML, Dublin S, et al. Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study. JAMA Intern Med. 2015;175(3):401-407.PubMedPubMedCentral
18.
go back to reference Reeve E, Bell JS, Hilmer SN. Barriers to Optimising Prescribing and Deprescribing in Older Adults with Dementia: A Narrative Review. Curr Clin Pharmacol. 2015;10(3):168-177.PubMed Reeve E, Bell JS, Hilmer SN. Barriers to Optimising Prescribing and Deprescribing in Older Adults with Dementia: A Narrative Review. Curr Clin Pharmacol. 2015;10(3):168-177.PubMed
19.
go back to reference Reeve E, Shakib S, Hendrix I, Roberts MS, Wiese MD. Review of deprescribing processes and development of an evidence-based, patient-centred deprescribing process. Br J Clin Pharmacol. 2014;78(4):738-747.PubMedPubMedCentral Reeve E, Shakib S, Hendrix I, Roberts MS, Wiese MD. Review of deprescribing processes and development of an evidence-based, patient-centred deprescribing process. Br J Clin Pharmacol. 2014;78(4):738-747.PubMedPubMedCentral
20.
go back to reference Scott IA, Hilmer SN, Reeve E, et al. Reducing inappropriate polypharmacy: the process of deprescribing. JAMA Intern Med. 2015;175(5):827-834.PubMed Scott IA, Hilmer SN, Reeve E, et al. Reducing inappropriate polypharmacy: the process of deprescribing. JAMA Intern Med. 2015;175(5):827-834.PubMed
21.
go back to reference Stacey D, Legare F, Col NF, et al. Decision aids for people facing health treatment or screening decisions. Cochrane Database Syst Rev. 2014;1:CD001431. Stacey D, Legare F, Col NF, et al. Decision aids for people facing health treatment or screening decisions. Cochrane Database Syst Rev. 2014;1:CD001431.
22.
go back to reference Karlawish J. Measuring Decision-Making Capacity in Cognitively Impaired Individuals. Neurosignals. 2008;16(1):91-98.PubMed Karlawish J. Measuring Decision-Making Capacity in Cognitively Impaired Individuals. Neurosignals. 2008;16(1):91-98.PubMed
23.
go back to reference Vick JB, Amjad H, Smith KC, et al. “Let him speak”: a descriptive qualitative study of the roles and behaviors of family companions in primary care visits among older adults with cognitive impairment. Int J Geriatr Psychiatry. 2018;33(1):e103-e112.PubMed Vick JB, Amjad H, Smith KC, et al. “Let him speak”: a descriptive qualitative study of the roles and behaviors of family companions in primary care visits among older adults with cognitive impairment. Int J Geriatr Psychiatry. 2018;33(1):e103-e112.PubMed
24.
go back to reference Wolff JL, Roter DL, Boyd CM, et al. Patient-Family Agenda Setting for Primary Care Patients with Cognitive Impairment: the SAME Page Trial. J Gen Intern Med. 2018;33(9):1478-1486.PubMedPubMedCentral Wolff JL, Roter DL, Boyd CM, et al. Patient-Family Agenda Setting for Primary Care Patients with Cognitive Impairment: the SAME Page Trial. J Gen Intern Med. 2018;33(9):1478-1486.PubMedPubMedCentral
25.
go back to reference Callahan CM, Unverzagt FW, Hui SL, Perkins AJ, Hendrie HC. Six-item screener to identify cognitive impairment among potential subjects for clinical research. Med Care. 2002;40(9):771-781.PubMed Callahan CM, Unverzagt FW, Hui SL, Perkins AJ, Hendrie HC. Six-item screener to identify cognitive impairment among potential subjects for clinical research. Med Care. 2002;40(9):771-781.PubMed
26.
go back to reference Doing qualitative research. In: Crabtree BF, Miller WL, eds. Newbury Park: Sage Publications; 1992. Doing qualitative research. In: Crabtree BF, Miller WL, eds. Newbury Park: Sage Publications; 1992.
27.
go back to reference Boeije H. A Purposeful Approach to the Constant Comparative Method in the Analysis of Qualitative Interviews. Qual Quant. 2002;36(4):391-409. Boeije H. A Purposeful Approach to the Constant Comparative Method in the Analysis of Qualitative Interviews. Qual Quant. 2002;36(4):391-409.
28.
go back to reference Hsieh HF, Shannon SE. Three approaches to qualitative content analysis. Qual Health Res. 2005;15(9):1277-1288.PubMed Hsieh HF, Shannon SE. Three approaches to qualitative content analysis. Qual Health Res. 2005;15(9):1277-1288.PubMed
29.
go back to reference Braddock CH, 3rd, Edwards KA, Hasenberg NM, Laidley TL, Levinson W. Informed decision making in outpatient practice: time to get back to basics. JAMA. 1999;282(24):2313-2320. Braddock CH, 3rd, Edwards KA, Hasenberg NM, Laidley TL, Levinson W. Informed decision making in outpatient practice: time to get back to basics. JAMA. 1999;282(24):2313-2320.
30.
go back to reference Elwyn G, Edwards A, Britten N. “Doing prescribing”: how doctors can be more effective. BMJ. 2003;327(7419):864-867.PubMedPubMedCentral Elwyn G, Edwards A, Britten N. “Doing prescribing”: how doctors can be more effective. BMJ. 2003;327(7419):864-867.PubMedPubMedCentral
31.
go back to reference Mold JW, Hamm RM, McCarthy LH. The law of diminishing returns in clinical medicine: how much risk reduction is enough? J Am Board Fam Med. 2010;23(3):371-375.PubMed Mold JW, Hamm RM, McCarthy LH. The law of diminishing returns in clinical medicine: how much risk reduction is enough? J Am Board Fam Med. 2010;23(3):371-375.PubMed
32.
go back to reference Farrell B, Black C, Thompson W, et al. Deprescribing antihyperglycemic agents in older persons: Evidence-based clinical practice guideline. Can Fam Physician. 2017;63(11):832-843.PubMedPubMedCentral Farrell B, Black C, Thompson W, et al. Deprescribing antihyperglycemic agents in older persons: Evidence-based clinical practice guideline. Can Fam Physician. 2017;63(11):832-843.PubMedPubMedCentral
33.
go back to reference Bjerre LM, Farrell B, Hogel M, et al. Deprescribing antipsychotics for behavioural and psychological symptoms of dementia and insomnia. Can Fam Physician. 2018;64(1):17.PubMedPubMedCentral Bjerre LM, Farrell B, Hogel M, et al. Deprescribing antipsychotics for behavioural and psychological symptoms of dementia and insomnia. Can Fam Physician. 2018;64(1):17.PubMedPubMedCentral
34.
go back to reference Reeve E, To J, Hendrix I, Shakib S, Roberts MS, Wiese MD. Patient barriers to and enablers of deprescribing: a systematic review. Drugs Aging 2013;30(10):793-807.PubMed Reeve E, To J, Hendrix I, Shakib S, Roberts MS, Wiese MD. Patient barriers to and enablers of deprescribing: a systematic review. Drugs Aging 2013;30(10):793-807.PubMed
35.
go back to reference Anderson K, Stowasser D, Freeman C, Scott I. Prescriber barriers and enablers to minimising potentially inappropriate medications in adults: a systematic review and thematic synthesis. BMJ Open. 2014;4(12):e006544.PubMedPubMedCentral Anderson K, Stowasser D, Freeman C, Scott I. Prescriber barriers and enablers to minimising potentially inappropriate medications in adults: a systematic review and thematic synthesis. BMJ Open. 2014;4(12):e006544.PubMedPubMedCentral
36.
go back to reference Kerns JW, Winter JD, Winter KM, Kerns CC, Etz RS. Caregiver perspectives about using antipsychotics and other medications for symptoms of dementia. Gerontologist. 2018;58(2):e35-e45. Kerns JW, Winter JD, Winter KM, Kerns CC, Etz RS. Caregiver perspectives about using antipsychotics and other medications for symptoms of dementia. Gerontologist. 2018;58(2):e35-e45.
37.
go back to reference Reeve E, Low LF, Hilmer SN. Beliefs and attitudes of older adults and carers about deprescribing of medications: a qualitative focus group study. Br J Gen Pract. 2016;66(649):e552-560.PubMedPubMedCentral Reeve E, Low LF, Hilmer SN. Beliefs and attitudes of older adults and carers about deprescribing of medications: a qualitative focus group study. Br J Gen Pract. 2016;66(649):e552-560.PubMedPubMedCentral
38.
go back to reference Reeve E, Wolff JL, Skehan M, Bayliss EA, Hilmer SN, Boyd CM. Assessment of attitudes toward deprescribing in older medicare beneficiaries in the United States. JAMA Intern Med. 2018;178(12):1673-1680.PubMedPubMedCentral Reeve E, Wolff JL, Skehan M, Bayliss EA, Hilmer SN, Boyd CM. Assessment of attitudes toward deprescribing in older medicare beneficiaries in the United States. JAMA Intern Med. 2018;178(12):1673-1680.PubMedPubMedCentral
39.
go back to reference Bynum JPW, Barre L, Reed C, Passow H. Participation of Very Old Adults in Healthcare Decisions. Med Decis Mak. .2014;34(2):216-230. Bynum JPW, Barre L, Reed C, Passow H. Participation of Very Old Adults in Healthcare Decisions. Med Decis Mak. .2014;34(2):216-230.
40.
go back to reference Belcher VN, Fried TR, Agostini JV, Tinetti ME. Views of older adults on patient participation in medication-related decision making. J Gen Intern Med. 2006;21(4):298-303.PubMedPubMedCentral Belcher VN, Fried TR, Agostini JV, Tinetti ME. Views of older adults on patient participation in medication-related decision making. J Gen Intern Med. 2006;21(4):298-303.PubMedPubMedCentral
41.
go back to reference Pisters R, Lane DA, Nieuwlaat R, de Vos CB, Crijns HJ, Lip GY. A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey. Chest. 2010;138(5):1093-1100.PubMed Pisters R, Lane DA, Nieuwlaat R, de Vos CB, Crijns HJ, Lip GY. A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey. Chest. 2010;138(5):1093-1100.PubMed
42.
go back to reference Lloyd-Jones DM, Braun LT, Ndumele CE, et al. Use of risk assessment tools to guide decision-making in the primary prevention of atherosclerotic cardiovascular disease. J Am Coll Cardiol. 2019;73(24):3153-3167.PubMed Lloyd-Jones DM, Braun LT, Ndumele CE, et al. Use of risk assessment tools to guide decision-making in the primary prevention of atherosclerotic cardiovascular disease. J Am Coll Cardiol. 2019;73(24):3153-3167.PubMed
43.
go back to reference Stewart TV, Loskutova N, Galliher JM, et al. Practice patterns, beliefs, and perceived barriers to care regarding dementia: a report from the American Academy of Family Physicians (AAFP) national research network. J Am Board Fam Med. 2014;27(2):275-283.PubMed Stewart TV, Loskutova N, Galliher JM, et al. Practice patterns, beliefs, and perceived barriers to care regarding dementia: a report from the American Academy of Family Physicians (AAFP) national research network. J Am Board Fam Med. 2014;27(2):275-283.PubMed
44.
go back to reference Frank C, Godwin M, Verma S, et al. What drugs are our frail elderly patients taking? Do drugs they take or fail to take put them at increased risk of interactions and inappropriate medication use? Can Fam Physician. 2001;47:1198-1204.PubMedPubMedCentral Frank C, Godwin M, Verma S, et al. What drugs are our frail elderly patients taking? Do drugs they take or fail to take put them at increased risk of interactions and inappropriate medication use? Can Fam Physician. 2001;47:1198-1204.PubMedPubMedCentral
45.
go back to reference Sudore RL, Boscardin J, Feuz MA, McMahan RD, Katen MT, Barnes DE. Effect of the PREPARE Website vs an Easy-to-Read Advance Directive on Advance Care Planning Documentation and Engagement Among Veterans: A Randomized Clinical Trial. JAMA Intern Med. 2017;177(8):1102-1109.PubMedPubMedCentral Sudore RL, Boscardin J, Feuz MA, McMahan RD, Katen MT, Barnes DE. Effect of the PREPARE Website vs an Easy-to-Read Advance Directive on Advance Care Planning Documentation and Engagement Among Veterans: A Randomized Clinical Trial. JAMA Intern Med. 2017;177(8):1102-1109.PubMedPubMedCentral
46.
go back to reference Tannenbaum C, Martin P, Tamblyn R, Benedetti A, Ahmed S. Reduction of inappropriate benzodiazepine prescriptions among older adults through direct patient education: the EMPOWER cluster randomized trial. JAMA Intern Med. 2014;174(6):890-898.PubMed Tannenbaum C, Martin P, Tamblyn R, Benedetti A, Ahmed S. Reduction of inappropriate benzodiazepine prescriptions among older adults through direct patient education: the EMPOWER cluster randomized trial. JAMA Intern Med. 2014;174(6):890-898.PubMed
47.
go back to reference Martin P, Tamblyn R, Benedetti A, Ahmed S, Tannenbaum C. Effect of a Pharmacist-Led Educational Intervention on Inappropriate Medication Prescriptions in Older Adults: The D-PRESCRIBE Randomized Clinical Trial. JAMA. 2018;320(18):1889-1898.PubMedPubMedCentral Martin P, Tamblyn R, Benedetti A, Ahmed S, Tannenbaum C. Effect of a Pharmacist-Led Educational Intervention on Inappropriate Medication Prescriptions in Older Adults: The D-PRESCRIBE Randomized Clinical Trial. JAMA. 2018;320(18):1889-1898.PubMedPubMedCentral
48.
go back to reference Thompson W, Reeve E, Moriarty F, et al. Deprescribing: Future directions for research. Res Soc Adm Pharm. 2019;15(6):801-805.PubMed Thompson W, Reeve E, Moriarty F, et al. Deprescribing: Future directions for research. Res Soc Adm Pharm. 2019;15(6):801-805.PubMed
49.
go back to reference Callahan CM, Sachs GA, Lamantia MA, Unroe KT, Arling G, Boustani MA. Redesigning systems of care for older adults with Alzheimer's disease. Health Aff (Millwood) 2014;33(4):626-632. Callahan CM, Sachs GA, Lamantia MA, Unroe KT, Arling G, Boustani MA. Redesigning systems of care for older adults with Alzheimer's disease. Health Aff (Millwood) 2014;33(4):626-632.
Metadata
Title
How Clinicians Discuss Medications During Primary Care Encounters Among Older Adults with Cognitive Impairment
Authors
Ariel R. Green, MD, MPH, PhD
Jennifer L. Wolff, PhD
Diane M. Echavarria, MS
Malcolm Chapman, BA
Annie Phung, MS
Devon Smith, BA
Cynthia M. Boyd, MD, MPH
Publication date
01-01-2020
Publisher
Springer US
Published in
Journal of General Internal Medicine / Issue 1/2020
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-019-05424-6

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