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Journal of General Internal Medicine
Published in: Journal of General Internal Medicine 8/2019

01-08-2019 | Opioids | Concise Research Reports

The Association of EHR Drug Safety Alerts and Co-prescribing of Opioids and Benzodiazepines

Authors: Laura Barrie Smith, BA, Ezra Golberstein, PhD, Kelly Anderson, RN, BSN, Tori Christiaansen, MD, Nicole Paterson, PharmD BCPS, Sonja Short, MD, Hannah T. Neprash, PhD

Published in: Journal of General Internal Medicine | Issue 8/2019

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Excerpt

Concurrent opioid and benzodiazepine use is associated with an increased risk of overdose, compared with opioid users who do not use benzodiazepines.1,2 Reflecting this safety concern, the Center for Disease Control and Prevention’s 2016 chronic pain guideline recommended against co-prescribing opioids and benzodiazepines.3 Nevertheless, clinicians frequently co-prescribe these medications. A recent estimate finds that 17% of opioid users concurrently use a benzodiazepine.1 …
Literature
1.
Sun EC, Dixit A, Humphreys K, Darnall BD, Baker LC, Mackey S. Association between concurrent use of prescription opioids and benzodiazepines and overdose: retrospective analysis. BMJ 2017;356:j760.CrossRef
2.
Hernandez I, He M, Brooks MM, Zhang Y. Exposure-Response Association Between Concurrent Opioid and Benzodiazepine Use and Risk of Opioid-Related Overdose in Medicare Part D Beneficiaries. JAMA Netw Open 2018;1(2):e180919.CrossRef
3.
Dowell D, Haegerich TM, Chou R. CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016. JAMA 2016;315(15):1624.CrossRef
4.
Genco EK, Forster JE, Flaten H, et al. Clinically Inconsequential Alerts: The Characteristics of Opioid Drug Alerts and Their Utility in Preventing Adverse Drug Events in the Emergency Department. Ann Emerg Med 2016;67(2):240–248.e3.CrossRef
5.
Ballo J, Boczenowski MLSS, Mccready BSRG, et al. Pain Management Resources to Support Clinical Decision Support Artifact Development: An Environmental Scan. Agency for Healthcare Research and Quality; 2017.
Metadata
Title
The Association of EHR Drug Safety Alerts and Co-prescribing of Opioids and Benzodiazepines
Authors
Laura Barrie Smith, BA
Ezra Golberstein, PhD
Kelly Anderson, RN, BSN
Tori Christiaansen, MD
Nicole Paterson, PharmD BCPS
Sonja Short, MD
Hannah T. Neprash, PhD
Publication date
01-08-2019
Publisher
Springer US
Published in
Journal of General Internal Medicine / Issue 8/2019
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-019-04985-w

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