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Published in: Journal of General Internal Medicine 10/2012

01-10-2012 | Original Research

Insurance Status, not Race, is Associated with Mortality After an Acute Cardiovascular Event in Maryland

Authors: Derek K. Ng, ScM, Daniel J. Brotman, MD, Bryan Lau, PhD, MHS, ScM, J. Hunter Young, MD, MHS

Published in: Journal of General Internal Medicine | Issue 10/2012

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ABSTRACT

BACKGROUND

It is unclear how lack of health insurance or otherwise being underinsured contributes to observed racial disparities in health outcomes related to cardiovascular disease.

OBJECTIVE

To determine the relative risk of death associated with insurance and race after hospital admission for an acute cardiovascular event.

DESIGN

Prospective cohort study in three hospitals in Maryland representing different demographics between 1993 and 2007.

PATIENTS

Patients with an incident admission who were either white or black, and had either private insurance, state-based insurance or were uninsured. 4,908 patients were diagnosed with acute myocardial infarction, 6,759 with coronary atherosclerosis, and 1,293 with stroke.

MAIN MEASURES

Demographic and clinical patient-level data were collected from an administrative billing database and neighborhood household income was collected from the 2000 US Census. The outcome of all-cause mortality was collected from the Social Security Death Master File.

KEY RESULTS

In an analysis adjusted for race, disease severity, location, neighborhood household income among other confounders, being underinsured was associated with an increased risk of death after myocardial infarction (relative hazard, 1.31 [95 % CI: 1.09, 1.59]), coronary atherosclerosis (relative hazard, 1.50 [95 % CI: 1.26, 1.80]) or stroke (relative hazard, 1.25 [95 % CI: 0.91, 1.72]). Black race was not associated with an increased risk of death after myocardial infarction (relative hazard, 1.03 [95 % CI: 0.85, 1.24]), or after stroke (relative hazard, 1.18 [95 % CI: 0.86, 1.61]) and was associated with a decreased risk of death after coronary atherosclerosis (relative hazard, 0.82 [95 % CI: 0.69, 0.98]).

CONCLUSIONS

Race was not associated with an increased risk of death, before or after adjustment. Being underinsured was strongly associated with death among those admitted with myocardial infarction, or a coronary atherosclerosis event. Our results support growing evidence implicating insurance status and socioeconomic factors as important drivers of health disparities, and potentially racial disparities.
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Literature
1.
go back to reference Murray CCJL, Kulkarni SC, Michaud C, Tomijima N, Bulzacchelli MT, Iandiorio TJ, et al. Eight Americas: investigating mortality disparities across races, counties, and race-counties in the United States. PLoS Medicine. 2006;3:e260.PubMedCrossRef Murray CCJL, Kulkarni SC, Michaud C, Tomijima N, Bulzacchelli MT, Iandiorio TJ, et al. Eight Americas: investigating mortality disparities across races, counties, and race-counties in the United States. PLoS Medicine. 2006;3:e260.PubMedCrossRef
2.
go back to reference Egan BM, Zhao Y, Axon RN. US trends in prevalence, awareness, treatment and control of hypertension, 1988-2008. JAMA. 2010;303:2043–50.PubMedCrossRef Egan BM, Zhao Y, Axon RN. US trends in prevalence, awareness, treatment and control of hypertension, 1988-2008. JAMA. 2010;303:2043–50.PubMedCrossRef
3.
go back to reference Gu Q, Burt VL, Paulose-Ram R, Yoon S, Gillum RF. High blood pressure and cardiovascular disease mortality risk among US adults: the third National Health and Nutrition Examination Survey and mortality follow-up study. Ann Epidemiol. 2008;18:302–9.PubMedCrossRef Gu Q, Burt VL, Paulose-Ram R, Yoon S, Gillum RF. High blood pressure and cardiovascular disease mortality risk among US adults: the third National Health and Nutrition Examination Survey and mortality follow-up study. Ann Epidemiol. 2008;18:302–9.PubMedCrossRef
4.
go back to reference Barnato AE, Lucas FL, Staiger D, Wennberg DE, Chandra A. Hospital-level racial disparities in acute myocardial infarction treatment and outcomes. Med Care. 2005;43:308–319.PubMedCrossRef Barnato AE, Lucas FL, Staiger D, Wennberg DE, Chandra A. Hospital-level racial disparities in acute myocardial infarction treatment and outcomes. Med Care. 2005;43:308–319.PubMedCrossRef
5.
go back to reference Budoff MJ, Nasir K, Mao S, et al. Ethnic differences of the presence and severity of coronary atherosclerosis. Atherosclerosis. 2006;187:343–350.PubMedCrossRef Budoff MJ, Nasir K, Mao S, et al. Ethnic differences of the presence and severity of coronary atherosclerosis. Atherosclerosis. 2006;187:343–350.PubMedCrossRef
6.
go back to reference Kivimäki M, Shipley MJ, Ferrie JE, Singh-Manoux A, Batty GD, Chandola T, Marmot MG, Smith GD. Best-practice interventions to reduce socioeconomic inequalities of coronary heart disease mortality in UK: a prospective occupational cohort study. Lancet. 2008;372:1648–54.PubMedCrossRef Kivimäki M, Shipley MJ, Ferrie JE, Singh-Manoux A, Batty GD, Chandola T, Marmot MG, Smith GD. Best-practice interventions to reduce socioeconomic inequalities of coronary heart disease mortality in UK: a prospective occupational cohort study. Lancet. 2008;372:1648–54.PubMedCrossRef
7.
go back to reference Thomas AJ, Eberly LE, Davey Smith G, Neaton JD, Stamler J. Race/ethnicity, income, major risk factors, and cardiovascular disease mortality. Am J Public Health. 2005;95:1417–23.PubMedCrossRef Thomas AJ, Eberly LE, Davey Smith G, Neaton JD, Stamler J. Race/ethnicity, income, major risk factors, and cardiovascular disease mortality. Am J Public Health. 2005;95:1417–23.PubMedCrossRef
8.
go back to reference Davey Smith G, Neaton JD, Wentworth D, Stamler R, Stamler J. Mortality differences between black and white men in the USA: contribution of income and other risk factors among men screened for the MRFIT. MRFIT Research Group. Multiple Risk Factor Intervention Tria. Lancet. 1998;351:934–9.PubMed Davey Smith G, Neaton JD, Wentworth D, Stamler R, Stamler J. Mortality differences between black and white men in the USA: contribution of income and other risk factors among men screened for the MRFIT. MRFIT Research Group. Multiple Risk Factor Intervention Tria. Lancet. 1998;351:934–9.PubMed
9.
go back to reference LaVeist TA. Disentangling race and socioeconomic status: a key to understanding health inequalities. J Urban Health. 2005;82(2 Suppl 3):26–34. LaVeist TA. Disentangling race and socioeconomic status: a key to understanding health inequalities. J Urban Health. 2005;82(2 Suppl 3):26–34.
10.
go back to reference Navarro V. Race or class versus race and class: mortality differentials in the United States. Lancet. 1990;336:1238–40.PubMedCrossRef Navarro V. Race or class versus race and class: mortality differentials in the United States. Lancet. 1990;336:1238–40.PubMedCrossRef
11.
go back to reference Groman R, Ginsburg J. American College of Physicians. Racial and ethnic disparities in health care: a position paper of the American College of Physicians. Ann Intern Med. 2004;141:225–32. Groman R, Ginsburg J. American College of Physicians. Racial and ethnic disparities in health care: a position paper of the American College of Physicians. Ann Intern Med. 2004;141:225–32.
12.
go back to reference Hauser TH, Ho KK. Accuracy of on-line databases in determining vital status. J Clin Epidemiol. 2001;54:1267–1270.PubMedCrossRef Hauser TH, Ho KK. Accuracy of on-line databases in determining vital status. J Clin Epidemiol. 2001;54:1267–1270.PubMedCrossRef
13.
go back to reference Fakhraei SH. Payments for physician services: an analysis of Maryland Medicaid reimbursement rates. Int J Healthc Tech Manag. 2006;7:129–42.CrossRef Fakhraei SH. Payments for physician services: an analysis of Maryland Medicaid reimbursement rates. Int J Healthc Tech Manag. 2006;7:129–42.CrossRef
14.
go back to reference Petersen KL, Marsland AL, Flory J, Votruba-Drzal E, Muldoon MF, Manuck SB. Community socioeconomic status is associated with circulating interleukin-6 and C-reactive protein. Psychosom Med. 2008;70:646–53.PubMedCrossRef Petersen KL, Marsland AL, Flory J, Votruba-Drzal E, Muldoon MF, Manuck SB. Community socioeconomic status is associated with circulating interleukin-6 and C-reactive protein. Psychosom Med. 2008;70:646–53.PubMedCrossRef
15.
go back to reference Scheffler RM, Brown TT, Syme L, Kawachi I, Tolstykh I, Iribarren C. Community-level social capital and recurrence of acute coronary syndrome. Soc Sci Med. 2008;66:1603–13.PubMedCrossRef Scheffler RM, Brown TT, Syme L, Kawachi I, Tolstykh I, Iribarren C. Community-level social capital and recurrence of acute coronary syndrome. Soc Sci Med. 2008;66:1603–13.PubMedCrossRef
16.
go back to reference Rabi DM, Edwards AL, Svenson LW, et al. Association of median household income with burden of coronary artery disease among individuals with diabetes. Circ Cardiovasc Qual Outcomes. 2010;3(1):48–53.PubMedCrossRef Rabi DM, Edwards AL, Svenson LW, et al. Association of median household income with burden of coronary artery disease among individuals with diabetes. Circ Cardiovasc Qual Outcomes. 2010;3(1):48–53.PubMedCrossRef
17.
go back to reference Reinier K, Thomas E, Andrusiek DL, Aufderheide TP, Brooks SC, Callaway CW, et al. Socioeconomic status and incidence of sudden cardiac arrest. CMAJ. 2011;183:1705–12.PubMedCrossRef Reinier K, Thomas E, Andrusiek DL, Aufderheide TP, Brooks SC, Callaway CW, et al. Socioeconomic status and incidence of sudden cardiac arrest. CMAJ. 2011;183:1705–12.PubMedCrossRef
18.
go back to reference Guilley E, Herrmann F, Rapin C, et al. Socioeconomic and living conditions are determinants of hip fracture incidence and age occurrence among community-dwelling elderly. Osteoporos Int. 2011;22:647–53.PubMedCrossRef Guilley E, Herrmann F, Rapin C, et al. Socioeconomic and living conditions are determinants of hip fracture incidence and age occurrence among community-dwelling elderly. Osteoporos Int. 2011;22:647–53.PubMedCrossRef
19.
go back to reference Jolly M, Mikolaitis RA, Shakoor N, Fogg LF, Block JA. Education, zip code-based annualized household income, and health outcomes in patients with systemic lupus erythematosus. J Rheumatol. 2010;37:1150–1157.PubMedCrossRef Jolly M, Mikolaitis RA, Shakoor N, Fogg LF, Block JA. Education, zip code-based annualized household income, and health outcomes in patients with systemic lupus erythematosus. J Rheumatol. 2010;37:1150–1157.PubMedCrossRef
20.
go back to reference Zeng Z. Multiple imputation for missing income data in population-based health surveillance. J Public Health Manag Pract. 2009;15:E12–21.PubMed Zeng Z. Multiple imputation for missing income data in population-based health surveillance. J Public Health Manag Pract. 2009;15:E12–21.PubMed
21.
go back to reference Nur U, Shack LG, Rachet B, Carpenter JR, Coleman MP. Modelling relative survival in the presence of incomplete data: a tutorial. Int J Epidemiol. 2010;39:118–128.PubMedCrossRef Nur U, Shack LG, Rachet B, Carpenter JR, Coleman MP. Modelling relative survival in the presence of incomplete data: a tutorial. Int J Epidemiol. 2010;39:118–128.PubMedCrossRef
22.
go back to reference Shrier I, Kahn SR, Steele RJ. Effect of early physical activity on long-term outcome after venous thrombosis. Clin J Sport Med. 2009;19:487–493.PubMedCrossRef Shrier I, Kahn SR, Steele RJ. Effect of early physical activity on long-term outcome after venous thrombosis. Clin J Sport Med. 2009;19:487–493.PubMedCrossRef
23.
go back to reference Rubin DB. Multiple imputation for nonresponse in surveys. New York: John Wiley & Sons; 1987.CrossRef Rubin DB. Multiple imputation for nonresponse in surveys. New York: John Wiley & Sons; 1987.CrossRef
24.
go back to reference Iezzoni L, ed. Risk adjustment for measuring healthcare outcomes. 3rd ed. Chicago: Health administration press; 2003. Iezzoni L, ed. Risk adjustment for measuring healthcare outcomes. 3rd ed. Chicago: Health administration press; 2003.
25.
go back to reference Nante N, Messina G, Cecchini M, et al. Sex differences in use of interventional cardiology persist after risk adjustment. J Epidemiol Community Health. 2009;63:203–208.PubMedCrossRef Nante N, Messina G, Cecchini M, et al. Sex differences in use of interventional cardiology persist after risk adjustment. J Epidemiol Community Health. 2009;63:203–208.PubMedCrossRef
26.
go back to reference Sedman AB, Bahl V, Bunting E, et al. Clinical redesign using all patient refined diagnosis related groups. Pediatrics. 2004;114:965–969.PubMedCrossRef Sedman AB, Bahl V, Bunting E, et al. Clinical redesign using all patient refined diagnosis related groups. Pediatrics. 2004;114:965–969.PubMedCrossRef
27.
go back to reference Romano PS, Chan BK. Risk-adjusting acute myocardial infarction mortality: are APR–DRGs the right tool? Health Serv Res. 2000;34:1469–1489.PubMed Romano PS, Chan BK. Risk-adjusting acute myocardial infarction mortality: are APR–DRGs the right tool? Health Serv Res. 2000;34:1469–1489.PubMed
28.
go back to reference Cleves M, Gould W, Gutierrez R, Marchenko Y. An introduction to survival analysis using Stata, 2nd Edition. Stata Press College Station, Texas: 2008. Cleves M, Gould W, Gutierrez R, Marchenko Y. An introduction to survival analysis using Stata, 2nd Edition. Stata Press College Station, Texas: 2008.
29.
go back to reference Lash TL, Fink AK. Semi-Automated Sensitivity Analysis to Assess Systematic Errors in Observational Data. Epidemiology. 2003;14:451–458.PubMed Lash TL, Fink AK. Semi-Automated Sensitivity Analysis to Assess Systematic Errors in Observational Data. Epidemiology. 2003;14:451–458.PubMed
30.
go back to reference Phillips CV. Quantifying and Reporting Uncertainty from Systematic Errors. Epidemiology. 2003;14:459–466.PubMed Phillips CV. Quantifying and Reporting Uncertainty from Systematic Errors. Epidemiology. 2003;14:459–466.PubMed
31.
go back to reference Kitahata MM, Gange SJ, Abraham AG, Merriman B, Saag MS, Justice AC, et al. Effect of early versus deferred antiretroviral therapy for HIV on survival. N Engl J Med. 2009;360:1815–26.PubMedCrossRef Kitahata MM, Gange SJ, Abraham AG, Merriman B, Saag MS, Justice AC, et al. Effect of early versus deferred antiretroviral therapy for HIV on survival. N Engl J Med. 2009;360:1815–26.PubMedCrossRef
32.
go back to reference Klein JP, Moeschberger ML. Survival Analysis: Techniques for Censored and Truncated Data 2nd edition. New York, NY: Springer; 2003. Klein JP, Moeschberger ML. Survival Analysis: Techniques for Censored and Truncated Data 2nd edition. New York, NY: Springer; 2003.
33.
go back to reference Spertus JA, Jones PG, Masoudi FA, Rumsfeld JS, Krumholz HM. Factors associated with racial differences in myocardial infarction outcomes. Ann Intern Med. 2009;150:314–24.PubMed Spertus JA, Jones PG, Masoudi FA, Rumsfeld JS, Krumholz HM. Factors associated with racial differences in myocardial infarction outcomes. Ann Intern Med. 2009;150:314–24.PubMed
34.
go back to reference Laveist T, Pollack K, Thorpe R Jr, Fesahazion R, Gaskin D. Place, not race: disparities dissipate in southwest Baltimore when blacks and whites live under similar conditions. Health Aff. 2011;30:1880–7.CrossRef Laveist T, Pollack K, Thorpe R Jr, Fesahazion R, Gaskin D. Place, not race: disparities dissipate in southwest Baltimore when blacks and whites live under similar conditions. Health Aff. 2011;30:1880–7.CrossRef
35.
go back to reference Fowler-Brown A, Corbie-Smith G, Garrett J, Lurie N. Risk of cardiovascular events and death–does insurance matter? J Gen Intern Med. 2007;22:502–507.PubMedCrossRef Fowler-Brown A, Corbie-Smith G, Garrett J, Lurie N. Risk of cardiovascular events and death–does insurance matter? J Gen Intern Med. 2007;22:502–507.PubMedCrossRef
36.
go back to reference Bleich SN, Thorpe RJ, Sharif-Harris H, Fesahazion R, Laveist TA. Social context explains race disparities in obesity among women. J Epidemiol Community Health. 2010;64:465–469.PubMedCrossRef Bleich SN, Thorpe RJ, Sharif-Harris H, Fesahazion R, Laveist TA. Social context explains race disparities in obesity among women. J Epidemiol Community Health. 2010;64:465–469.PubMedCrossRef
37.
go back to reference Borell LN. Diez Roux AV, Rose K, Catellier D, Clark BL, Atherosclerosis risk in communities study: neighborhood characteristics and mortality in the atherosclerosis risk in communities study. Int J Epidemiol. 2004;33:398–407.CrossRef Borell LN. Diez Roux AV, Rose K, Catellier D, Clark BL, Atherosclerosis risk in communities study: neighborhood characteristics and mortality in the atherosclerosis risk in communities study. Int J Epidemiol. 2004;33:398–407.CrossRef
38.
go back to reference Diez Roux AV, Merkin SS, Arnett D, Chambless L, Massing M, Nieto FJ, Sorlie P, Szklo M, Tyroler HA, Watson RL. Community of residence and incidence of coronary heart disease. N Engl J Med. 2001. Diez Roux AV, Merkin SS, Arnett D, Chambless L, Massing M, Nieto FJ, Sorlie P, Szklo M, Tyroler HA, Watson RL. Community of residence and incidence of coronary heart disease. N Engl J Med. 2001.
Metadata
Title
Insurance Status, not Race, is Associated with Mortality After an Acute Cardiovascular Event in Maryland
Authors
Derek K. Ng, ScM
Daniel J. Brotman, MD
Bryan Lau, PhD, MHS, ScM
J. Hunter Young, MD, MHS
Publication date
01-10-2012
Publisher
Springer-Verlag
Published in
Journal of General Internal Medicine / Issue 10/2012
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-012-2147-9

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