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Published in: Journal of General Internal Medicine 6/2007

01-06-2007 | Original Article

Strategies for Coping in a Complex World: Adherence Behavior Among Older Adults with Chronic Illness

Authors: Rachel A. Elliott, PhD, Dennis Ross-Degnan, ScD, Alyce S. Adams, PhD, Dana Gelb Safran, ScD, Stephen B. Soumerai, ScD

Published in: Journal of General Internal Medicine | Issue 6/2007

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Abstract

Background

Increasing numbers of medicines increase nonadherence. Little is known about how older adults manage multiple medicines for multiple illnesses.

Objectives

To explore how older adults with multiple illnesses make choices about medicines.

Design

Semistructured interviews with older adults taking several medications. Accounts of respondents’ medicine-taking behavior were collected.

Participants

Twenty community-dwelling seniors with health insurance, in Eastern Massachusetts, aged 67–90, (4–12 medicines, 3–9 comorbidities).

Approach

Qualitative analysis using constant comparison to explain real choices made about medicines in the past (“historical”) and hypothetical (“future”) choices.

Results

Respondents reported both past (“historical”) choices and hypothetical (“future”) choices between medicines. Although people discussed effectiveness and future risk of the disease when prompted to prioritize their medicines (future choices), key factors leading to nonadherence (historical choices) were costs and side effects. Specific choices were generally dominated by 1 factor, and respondents rarely reported making explicit trade-offs between different factors. Factors affecting 1 choice were not necessarily the same as those affecting another choice in the same person. There was no evidence of “adherent” personalities.

Conclusion

Prescribing a new medicine, a change in provider or copayment can provoke new choices about both new and existing medications in older adults with multiple morbidities.
Literature
1.
go back to reference DiMatteo MR. Variations in patients’ adherence to medical recommendations: a quantitative review of 50 years of research.[see comment]. Med Care 2004;42:200–9, Mar.PubMedCrossRef DiMatteo MR. Variations in patients’ adherence to medical recommendations: a quantitative review of 50 years of research.[see comment]. Med Care 2004;42:200–9, Mar.PubMedCrossRef
3.
go back to reference Dartnell JGA, Anderson RP, Chohan V, et al. Hospitalisation for adverse events related to drug therapy: incidence, avoidability and costs. Med J Aust. 1996;164:659–62.PubMed Dartnell JGA, Anderson RP, Chohan V, et al. Hospitalisation for adverse events related to drug therapy: incidence, avoidability and costs. Med J Aust. 1996;164:659–62.PubMed
4.
go back to reference Psaty BM, Koepsell TD, Wagner EH, lo Gerfo JP, Inui TS. The relative risk of incident coronary heart disease associated with recently stopping the use of B-blockers. J Am Med Assoc. 1990;263(12):1653–7.CrossRef Psaty BM, Koepsell TD, Wagner EH, lo Gerfo JP, Inui TS. The relative risk of incident coronary heart disease associated with recently stopping the use of B-blockers. J Am Med Assoc. 1990;263(12):1653–7.CrossRef
5.
go back to reference Weiden PJ, Olfson M. Cost of relapse in schizophrenia. Schizophr Bull. 1995;21(3):419–29.PubMed Weiden PJ, Olfson M. Cost of relapse in schizophrenia. Schizophr Bull. 1995;21(3):419–29.PubMed
6.
go back to reference Lau DT, Nau DP. Oral antihypoglycaemic medication nonadherence and subsequent hospitalization among individuals with Type 2 diabetes. Diabetes Care 2004;27:2149–53.PubMedCrossRef Lau DT, Nau DP. Oral antihypoglycaemic medication nonadherence and subsequent hospitalization among individuals with Type 2 diabetes. Diabetes Care 2004;27:2149–53.PubMedCrossRef
7.
go back to reference Balkrishnan R, Rajagopalan R, Camacho FT, Huston SA, Murray FT, Anderson RT. Predictors of medication adherence and associated health care costs in an older population with type 2 diabetes mellitus: a longitudinal cohort study. Clin Ther. 2003;(11):2958–71. Balkrishnan R, Rajagopalan R, Camacho FT, Huston SA, Murray FT, Anderson RT. Predictors of medication adherence and associated health care costs in an older population with type 2 diabetes mellitus: a longitudinal cohort study. Clin Ther. 2003;(11):2958–71.
8.
go back to reference Lewis A. Noncompliance: a $100 billion problem. Remington Rep. 1997;5:14–5. Lewis A. Noncompliance: a $100 billion problem. Remington Rep. 1997;5:14–5.
9.
go back to reference Zuger A. The ‘other’ drug problem: forgetting to take them. The New York Times 1998 Jun 2. Zuger A. The ‘other’ drug problem: forgetting to take them. The New York Times 1998 Jun 2.
10.
go back to reference DiMatteo MR. Social support and patient adherence to medical treatment: a meta-analysis. Health Psychol. 2004;(2):207–18. DiMatteo MR. Social support and patient adherence to medical treatment: a meta-analysis. Health Psychol. 2004;(2):207–18.
11.
go back to reference Lexchin J, Grootendorst P. Effects of prescription drug user fees on drug and health servcies use and on health status in vulnerable popluations: a systematic review of the evidence. Int J Health Serv. 2004;34:101–22.PubMedCrossRef Lexchin J, Grootendorst P. Effects of prescription drug user fees on drug and health servcies use and on health status in vulnerable popluations: a systematic review of the evidence. Int J Health Serv. 2004;34:101–22.PubMedCrossRef
12.
go back to reference Soumerai SB. Unintended outcomes of Medicaid drug cost-containment policies on the chronically mentally ill. J Clin Psychiatry. 2003;64 [supp 17]:19–22.PubMed Soumerai SB. Unintended outcomes of Medicaid drug cost-containment policies on the chronically mentally ill. J Clin Psychiatry. 2003;64 [supp 17]:19–22.PubMed
13.
go back to reference Vik SA, Maxwell CJ, Hogan DB. Measurement, correlates and health outcomes of medication adherence among seniors. Ann Pharmacother. 2004;38:303–12.PubMed Vik SA, Maxwell CJ, Hogan DB. Measurement, correlates and health outcomes of medication adherence among seniors. Ann Pharmacother. 2004;38:303–12.PubMed
14.
go back to reference Lexchin J, Grootendorst P. Effects of prescription drug user fees on drug and health services use and on health status in vulnerable populations: a systematic review of the evidence. Int J Health Serv. 2004;34:101–22.PubMedCrossRef Lexchin J, Grootendorst P. Effects of prescription drug user fees on drug and health services use and on health status in vulnerable populations: a systematic review of the evidence. Int J Health Serv. 2004;34:101–22.PubMedCrossRef
15.
go back to reference Darnell JC, Murray MD, Martz BL, Weinberger M. Medication use by ambulatory elderly. An in-home survey. J Am Geriatr Soc. 1986;34:1–4, Jan.PubMed Darnell JC, Murray MD, Martz BL, Weinberger M. Medication use by ambulatory elderly. An in-home survey. J Am Geriatr Soc. 1986;34:1–4, Jan.PubMed
16.
go back to reference McElnay JC, McCallion CR, al Deagi F, Scott M. Self-reported medication non-compliance in the elderly. Eur J Clin Pharmacol. 1997;53:171–8.PubMedCrossRef McElnay JC, McCallion CR, al Deagi F, Scott M. Self-reported medication non-compliance in the elderly. Eur J Clin Pharmacol. 1997;53:171–8.PubMedCrossRef
17.
go back to reference Coons SJ, Sheahan SL, Martin SS, Hendricks J, Robbins CA, Johnson JA. Predictors of medication noncompliance in a sample of older adults. Clin Ther. 1994;16:110–7, Jan.PubMed Coons SJ, Sheahan SL, Martin SS, Hendricks J, Robbins CA, Johnson JA. Predictors of medication noncompliance in a sample of older adults. Clin Ther. 1994;16:110–7, Jan.PubMed
18.
go back to reference Avorn J, Monette J, Lacour A, et al. Persistence of use of lipid-lowering medications: a cross-national study. J Am Med Assoc. 1998;279:1458–62, May 13.CrossRef Avorn J, Monette J, Lacour A, et al. Persistence of use of lipid-lowering medications: a cross-national study. J Am Med Assoc. 1998;279:1458–62, May 13.CrossRef
19.
go back to reference Gurwitz JH, Glynn RJ, Monane M, et al. Treatment for glaucoma: adherence by the elderly. Am J Public Health. 1993;83:711–6, May.PubMedCrossRef Gurwitz JH, Glynn RJ, Monane M, et al. Treatment for glaucoma: adherence by the elderly. Am J Public Health. 1993;83:711–6, May.PubMedCrossRef
20.
go back to reference Monane M, Bohn RL, Gurwitz JH, Glynn RJ, Levin R, Avorn J. The effects of initial drug choice and comorbidity on antihypertensive therapy compliance: results from a population-based study in the elderly. Am J Hypertens. 1997;10:697–704, Jul.PubMedCrossRef Monane M, Bohn RL, Gurwitz JH, Glynn RJ, Levin R, Avorn J. The effects of initial drug choice and comorbidity on antihypertensive therapy compliance: results from a population-based study in the elderly. Am J Hypertens. 1997;10:697–704, Jul.PubMedCrossRef
21.
go back to reference Cox ER, Henderson RR. Prescription use behaviour among Medicare beneficiaries with capped prescription benefits. J Manag Care Pharm. 2002;8:360–4.PubMed Cox ER, Henderson RR. Prescription use behaviour among Medicare beneficiaries with capped prescription benefits. J Manag Care Pharm. 2002;8:360–4.PubMed
22.
go back to reference Fortess EE, Soumerai SB, McLaughlin TJ, Ross-Degnan D. Utilization of essential medications by vulnerable older people after a drug benefit cap: importance of mental disorders, chronic pain and practice setting. J Am Geriatr Soc. 2001;49:793–7.PubMedCrossRef Fortess EE, Soumerai SB, McLaughlin TJ, Ross-Degnan D. Utilization of essential medications by vulnerable older people after a drug benefit cap: importance of mental disorders, chronic pain and practice setting. J Am Geriatr Soc. 2001;49:793–7.PubMedCrossRef
23.
go back to reference Piette JD, Heisler M, Wagner TH. Cost-related medication underuse. Do patients with chronic illnesses tell their doctors? Arch Intern Med 2004;164:1749–55.PubMedCrossRef Piette JD, Heisler M, Wagner TH. Cost-related medication underuse. Do patients with chronic illnesses tell their doctors? Arch Intern Med 2004;164:1749–55.PubMedCrossRef
24.
go back to reference Schafheutle EI, Hassell K, Noyce PR, Weiss MC. Access to medicines: cost as an influence on the views and behaviour of patients. Health Soc Care Community. 2002;10:187–95.PubMedCrossRef Schafheutle EI, Hassell K, Noyce PR, Weiss MC. Access to medicines: cost as an influence on the views and behaviour of patients. Health Soc Care Community. 2002;10:187–95.PubMedCrossRef
25.
go back to reference Park DC, Hertzog C, Leventhal H, et al. Medication adherence in rheumatoid arthritis patients: older is wiser. J Am Geriatr Soc. 1999;47:172–83.PubMed Park DC, Hertzog C, Leventhal H, et al. Medication adherence in rheumatoid arthritis patients: older is wiser. J Am Geriatr Soc. 1999;47:172–83.PubMed
26.
go back to reference Pound P, Britten N, Morgan M, et al. Resisting medicines: a synthesis of qualitative studies of medicine taking. Soc Sci Med. 2005;61:133–55.PubMedCrossRef Pound P, Britten N, Morgan M, et al. Resisting medicines: a synthesis of qualitative studies of medicine taking. Soc Sci Med. 2005;61:133–55.PubMedCrossRef
27.
go back to reference Donovan J, Blake DR. Patient non-compliance: deviance or reasoned decision-making. Soc Sci Med. 1992;34:507–13.PubMedCrossRef Donovan J, Blake DR. Patient non-compliance: deviance or reasoned decision-making. Soc Sci Med. 1992;34:507–13.PubMedCrossRef
28.
go back to reference Horne R, Weinman J. Patients’ beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. J Psychosom Res. 1999;47(6):555–67.PubMedCrossRef Horne R, Weinman J. Patients’ beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. J Psychosom Res. 1999;47(6):555–67.PubMedCrossRef
29.
go back to reference Dowell J, Hudson H. A qualitative study of medicine-taking behaviour in primary care. Fam Pract 1997;14:369–75.PubMedCrossRef Dowell J, Hudson H. A qualitative study of medicine-taking behaviour in primary care. Fam Pract 1997;14:369–75.PubMedCrossRef
30.
go back to reference Slovic P, Finucane M, Peters E, MacGregor DG. Risk as analysis and risk as feelings: some thoughts about affect, reason, risk and rationality. Risk Anal. 2004;24:311–22.PubMedCrossRef Slovic P, Finucane M, Peters E, MacGregor DG. Risk as analysis and risk as feelings: some thoughts about affect, reason, risk and rationality. Risk Anal. 2004;24:311–22.PubMedCrossRef
31.
go back to reference Kahneman D, Slovic P, Tversky A. Judgement Under Uncertainty: Heuristics and Biases. Cambridge: Cambridge University Press; 1982. Kahneman D, Slovic P, Tversky A. Judgement Under Uncertainty: Heuristics and Biases. Cambridge: Cambridge University Press; 1982.
32.
go back to reference Katapodi MC, Facione NC, Humphreys JC, Dodd MJ. Perceived breast cancer risk: heuristic reasoning and search for a dominance structure. Soc Sci Med. 2005;60:421–32.PubMedCrossRef Katapodi MC, Facione NC, Humphreys JC, Dodd MJ. Perceived breast cancer risk: heuristic reasoning and search for a dominance structure. Soc Sci Med. 2005;60:421–32.PubMedCrossRef
33.
go back to reference Green J. Commentary: grounded theory and the constant comparative method. BMJ 1998;316(7137):1064–5.PubMed Green J. Commentary: grounded theory and the constant comparative method. BMJ 1998;316(7137):1064–5.PubMed
34.
go back to reference Crabtree BJ, Miller WL. Using codes and code manuals. In: Crabtree BF, Miller WL, eds. Doing Qualitative Research. 2nd ed. London: Sage Publications; 1999:163–77. Crabtree BJ, Miller WL. Using codes and code manuals. In: Crabtree BF, Miller WL, eds. Doing Qualitative Research. 2nd ed. London: Sage Publications; 1999:163–77.
35.
go back to reference Laws MB, Wilson IB, Bowser DM, Kerr SE. Taking antiretroviral therapy for hiv infection: learning from patients’ stories. J Gen Intern Med. 2000;15(12):848–58.PubMedCrossRef Laws MB, Wilson IB, Bowser DM, Kerr SE. Taking antiretroviral therapy for hiv infection: learning from patients’ stories. J Gen Intern Med. 2000;15(12):848–58.PubMedCrossRef
36.
go back to reference Kahneman D. Experienced utility and objective happiness: a moment-based approach. In: Kahneman D, Tversky A, eds. Choices, Values and Frames. New York: Cambridge University Press and Russell Sage Foundation; 2000: 673–92. Kahneman D. Experienced utility and objective happiness: a moment-based approach. In: Kahneman D, Tversky A, eds. Choices, Values and Frames. New York: Cambridge University Press and Russell Sage Foundation; 2000: 673–92.
37.
go back to reference Coulter A. The Autonomous Patient. Ending paternalism in health care. London: The Nuffield Trust; 2002. Coulter A. The Autonomous Patient. Ending paternalism in health care. London: The Nuffield Trust; 2002.
38.
go back to reference Wilson IB, Rogers WH, Chang H, Safran DG. Cost-related skipping of medications and other treatments among medicare beneficiaries between 1998 and 2000. Results of a National Study. J Gen Intern Med. 2005;20:715–20.PubMedCrossRef Wilson IB, Rogers WH, Chang H, Safran DG. Cost-related skipping of medications and other treatments among medicare beneficiaries between 1998 and 2000. Results of a National Study. J Gen Intern Med. 2005;20:715–20.PubMedCrossRef
39.
go back to reference Safran DG, Taira DA, Rogers WH, Kosinski M, Ware JE, Tarlov AR. Linking primary care performance to outcomes of care. J Fam Pract. 1998;47:213–20.PubMed Safran DG, Taira DA, Rogers WH, Kosinski M, Ware JE, Tarlov AR. Linking primary care performance to outcomes of care. J Fam Pract. 1998;47:213–20.PubMed
40.
go back to reference Elliott RA, Majumdar SR, Gillick MR, Soumerai SB. Medicare drug benefit: benefits and consequences for the poor and the disabled. N Engl J Med. 2005;353:2739–41.PubMedCrossRef Elliott RA, Majumdar SR, Gillick MR, Soumerai SB. Medicare drug benefit: benefits and consequences for the poor and the disabled. N Engl J Med. 2005;353:2739–41.PubMedCrossRef
41.
go back to reference Shield RR, Wetle T, Teno J, Miller SC, Welch L. Physicians “missing in action”: family perspectives on physician and staffing problems in end-of-life care in the nursing home.[see comment]. J Am Geriatr Soc. 2005;53(10):1651–7.PubMedCrossRef Shield RR, Wetle T, Teno J, Miller SC, Welch L. Physicians “missing in action”: family perspectives on physician and staffing problems in end-of-life care in the nursing home.[see comment]. J Am Geriatr Soc. 2005;53(10):1651–7.PubMedCrossRef
Metadata
Title
Strategies for Coping in a Complex World: Adherence Behavior Among Older Adults with Chronic Illness
Authors
Rachel A. Elliott, PhD
Dennis Ross-Degnan, ScD
Alyce S. Adams, PhD
Dana Gelb Safran, ScD
Stephen B. Soumerai, ScD
Publication date
01-06-2007
Publisher
Springer-Verlag
Published in
Journal of General Internal Medicine / Issue 6/2007
Print ISSN: 0884-8734
Electronic ISSN: 1525-1497
DOI
https://doi.org/10.1007/s11606-007-0193-5

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