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Japanese Journal of Radiology
Published in: Japanese Journal of Radiology 12/2016

01-12-2016 | Original Article

Diagnosis of early colorectal cancer invasion depth by quantitative evaluation of the basal indentation in CT colonography

Authors: Mitsutoshi Miyasaka, Daisuke Tsurumaru, Yusuke Nishimuta, Yoshiki Asayama, Satoshi Kawanami, Eiji Oki, Minako Hirahashi, Hiroshi Honda

Published in: Japanese Journal of Radiology | Issue 12/2016

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Abstract

Objective

To investigate the feasibility of diagnosing the invasion depth of early colorectal cancer (CRC) by quantitatively evaluating the basal indentation (BI)—i.e., the intestinal lateral deformity—in CT colonography (CTC).

Materials and methods

34 early CRCs (13 Tis CRCs and 21 T1 CRCs) in 32 patients who underwent a preoperative CTC were retrospectively examined. Two radiologists calculated the depth of the BI on a computed tomographic air-contrast enema (CT enema) image, the depth of the BI due to the geometric function (BI-G) on a cross-sectional multiplanar reconstruction (CS-MPR) image, and the ratio of the BI to the BI-G (i.e., the “BI ratio”) for each lesion. The BI ratios of the Tis and T1 CRCs were compared.

Results

The BI ratios were significantly higher in the T1 CRCs than in the Tis CRCs (p < 0.0001). The optimum cutoff value of the BI ratio for differentiating the T1 CRCs from the Tis CRCs was 1.64, with a sensitivity, specificity, and area under the curve of 90.5 %, 100 %, and 0.974, respectively.

Conclusions

We have demonstrated for the first time that quantitatively evaluating the BI can improve the accuracy of diagnosis of early CRC invasion depth.
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Metadata
Title
Diagnosis of early colorectal cancer invasion depth by quantitative evaluation of the basal indentation in CT colonography
Authors
Mitsutoshi Miyasaka
Daisuke Tsurumaru
Yusuke Nishimuta
Yoshiki Asayama
Satoshi Kawanami
Eiji Oki
Minako Hirahashi
Hiroshi Honda
Publication date
01-12-2016
Publisher
Springer Japan
Published in
Japanese Journal of Radiology / Issue 12/2016
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-016-0586-7

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