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01-06-2019 | Note

Four limonoids from the seeds extract of Sandoricum koetjape

Authors: Miranti B. Bumi, Leny Heliawaty, Elvira Hermawati, Yana M. Syah

Published in: Journal of Natural Medicines | Issue 3/2019

Abstract

Three andirobin- and one trijugin-class limonoids, named koetjapins A-D (1–4), have been isolated from the seed extracts of Sandoricum koetjape. The structures of these compounds were determined by extensive NMR and mass spectral data, and the chemotaxonomic significance of these limonoids in the family Meliaceae is highlighted. Preliminary biological activity showed that only compound 4 has significant inhibitory activity against P-388 cells, while antibacterial tests showed that none of these compounds were active.

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Title: Four limonoids from the seeds extract of Sandoricum koetjape
Authors: Miranti B. Bumi
Leny Heliawaty
Elvira Hermawati
Yana M. Syah
Publication date: 01-06-2019
Publisher: Springer Singapore
Published in: Journal of Natural Medicines / Issue 3/2019
Print ISSN: 1340-3443
Electronic ISSN: 1861-0293
DOI: https://doi.org/10.1007/s11418-019-01303-w

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