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Sleep and Breathing
Published in: Sleep and Breathing 4/2022

05-02-2022 | Bronchial Asthma | Sleep Breathing Physiology and Disorders • Original Article

Pulmonary disease and periodontal health: a meta-analysis

Authors: ZeSheng Wu, Chen Xiao, FangHui Chen, Yi Wang, ZhiDong Guo

Published in: Sleep and Breathing | Issue 4/2022

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Abstract

Objective

Research has shown a positive relationship between pulmonary and periodontal disease. However, the relationship remains unclear. The aim of this meta-analysis was to evaluate the associations between pulmonary disease and periodontal health.

Materials and methods

MEDLINE, PubMed, EMBASE, Web of Science, Science Citation Index, Wanfang, and CNKI were searched for all the relevant studies of relationship between pulmonary disease and periodontal health. Weighted mean difference (WMD)/odds ratio (OR) with 95% confidence interval (CI) was used to assess the strength of the association.

Results

Thirty-seven studies were included in this meta-analysis. Pooled analysis showed a significant association between pulmonary and periodontal disease (adjusted OR, 1.93; 95%CI: 1.60–2.33; P < 0.05), and pooled adjusted OR was 1.64, 3.03, and 2.21 in COPD, asthma, and pneumonia, respectively. The pooled analysis also showed that patients with pulmonary disease suffered from worse periodontal health as most periodontal indexes in those patients were poorer.

Conclusions

There is a strong association between pulmonary disease and periodontal health. Clinical trials analyzing the causality and pathological basis of the association of these two diseases are needed.
Appendix
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Metadata
Title
Pulmonary disease and periodontal health: a meta-analysis
Authors
ZeSheng Wu
Chen Xiao
FangHui Chen
Yi Wang
ZhiDong Guo
Publication date
05-02-2022
Publisher
Springer International Publishing
Published in
Sleep and Breathing / Issue 4/2022
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-022-02577-3

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