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Published in: Sleep and Breathing 3/2022

26-08-2021 | Coronary Heart Disease | Methods • Review

Sleep duration and health outcomes: an umbrella review

Authors: Jin Li, Dehong Cao, Yin Huang, Zeyu Chen, Ruyi Wang, Qiang Dong, Qiang Wei, Liangren Liu

Published in: Sleep and Breathing | Issue 3/2022

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Abstract

Purpose

To collect existing evidence on the relationship between sleep duration and health outcomes.

Methods

A thorough search was conducted in PubMed, Web of Science, Embase, and the Cochrane Database of Systematic Reviews from inception to January, 2021. Meta-analyses of observational and interventional studies were eligible if they examined the associations between sleep duration and human health.

Results

In total, this umbrella review identified 69 meta-analyses with 11 outcomes for cancers and 30 outcomes for non-cancer conditions. Inappropriate sleep durations may significantly elevate the risk for cardiovascular disease (CVD), cognitive decline, coronary heart disease (CHD), depression, falls, frailty, lung cancer, metabolic syndrome (MS), and stroke. Dose–response analysis revealed that a 1-h reduction per 24 hours is associated with an increased risk by 3–11% of all-cause mortality, CHD, osteoporosis, stroke, and T2DM among short sleepers. Conversely, a 1-h increment in long sleepers is associated with a 7–17% higher risk of stroke mortality, CHD, stroke, and T2DM in adults.

Conclusion

Inappropriate sleep duration is a risk factor for developing non-cancer conditions. Decreasing and increasing sleep hours towards extreme sleep durations are associated with poor health outcomes.
Appendix
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Metadata
Title
Sleep duration and health outcomes: an umbrella review
Authors
Jin Li
Dehong Cao
Yin Huang
Zeyu Chen
Ruyi Wang
Qiang Dong
Qiang Wei
Liangren Liu
Publication date
26-08-2021
Publisher
Springer International Publishing
Published in
Sleep and Breathing / Issue 3/2022
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-021-02458-1

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