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Sleep and Breathing

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28-06-2021 | Sleep Apnea | Sleep Breathing Physiology and Disorders • Original Article

A validation study of an esophageal probe–based polygraph against polysomnography in obstructive sleep apnea

Authors: Thorarinn Arnar Olafsson, Eivind Andreas Steinsvik, Gregor Bachmann-Harildstad, Harald Hrubos-Strøm

Published in: Sleep and Breathing | Issue 2/2022

Abstract

Study objectives

The aim of this study was to validate the automatically scored results of an esophageal probe–based polygraph system (ApneaGraph® Spiro) against manually scored polysomnography (Nox A1, PSG) results. We compared the apnea–hypopnea index, oxygen saturation index, and respiratory disturbance index of the devices.

Methods

Consenting patients, referred for obstructive sleep apnea workup, were tested simultaneously with the ApneaGraph® Spiro and Nox A1® polysomnograph. Each participant made one set of simultaneous registrations for one night. PSG results were scored independently. Apnea–hypopnea index, oxygen desaturation index, and respiratory disturbance index were compared using Pearson’s correlation and scatter plots. Sensitivity, specificity, and positive likelihood ratio of all indices at 5, 15, and 30 were calculated.

Results

A total of 83 participants had successful registrations. The apnea–hypopnea index showed sensitivity of 0.83, specificity of 0.95, and a positive likelihood ratio of 5.11 at an index cutoff of 15. At a cutoff of 30, the positive likelihood ratio rose to 31.43. The respiratory disturbance index showed high sensitivity (> 0.9) at all cutoffs, but specificity was below 0.5 at all cutoffs. Scatterplots revealed overestimation in mild OSA and underestimation in severe OSA for all three indices.

Conclusions

The ApneaGraph® Spiro performed acceptably when OSA was defined by an AHI of 15. The equipment overestimated mild OSA and underestimated severe OSA, compared to the PSG.

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Title: A validation study of an esophageal probe–based polygraph against polysomnography in obstructive sleep apnea
Authors: Thorarinn Arnar Olafsson
Eivind Andreas Steinsvik
Gregor Bachmann-Harildstad
Harald Hrubos-Strøm
Publication date: 28-06-2021
Publisher: Springer International Publishing
Keywords: Sleep Apnea
Polysomnography
Published in: Sleep and Breathing / Issue 2/2022
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI: https://doi.org/10.1007/s11325-021-02374-4

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A validation study of an esophageal probe–based polygraph against polysomnography in obstructive sleep apnea

Abstract

Study objectives

Methods

Results

Conclusions

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Abstract

Study objectives

Methods

Results

Conclusions

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