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Published in: Oral Radiology 1/2020

01-01-2020 | Computed Tomography | Original Article

Desmoplastic ameloblastoma of the jaw: CT and MR imaging findings

Authors: Akira Baba, Hiroya Ojiri, Manabu Minami, Takashi Hiyama, Mitsuru Matsuki, Tazuko K. Goto, Satoshi Tatsuno, Kazuhiko Hashimoto, Yumi Okuyama, Nobuhiro Ogino, Hideomi Yamauchi, Takuji Mogami

Published in: Oral Radiology | Issue 1/2020

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Abstract

Objectives

Desmoplastic ameloblastoma (DA) is one of the rare pathological variants of ameloblastoma. The purpose of this study is to investigate CT and MR imaging findings of DA.

Methods

We retrospectively evaluated six DA cases that were gathered from four different hospitals and confirmed histopathologically with resected specimens. Two radiologists who specialized in head and neck imaging retrospectively interpreted and reviewed pretreatment CT and MR imaging findings.

Results

On CT, all DAs presented with well-defined border and low internal attenuation. Regarding locularity, five cases showed honeycomb-like lesions and one showed a unilocular lesion. Bone expansions were seen in all patients and located on the labial side in four cases. On MR imaging, all DAs showed well-defined borders and solid moderately low signal intensities with small cystic high signal intensities on T2-weighted images and intermediate signal intensity on T1-weighted images. Five DAs showed linear low signal intensity on T1- and T2-weighted images. Gd-DTPA-enhanced MR imaging was performed in three cases, and all cases showed moderate enhancement. Dynamic-enhanced MR imaging was performed in two of them, and persistent enhancement was detected.

Conclusion

Our findings strongly suggest that MR imaging should also be consulted, particularly for honeycomb-like lesions with well-defined margins, bone expansion and anterior location on radiographs or CT. Additionally, findings by MR imaging such as solid low-signal-intensity, hyperintense cystic foci and persistent enhancement pattern will suggest the diagnosis of DA.
Literature
1.
go back to reference Eversole LR, Leider AS, Hansen LS. Ameloblastomas with pronounced desmoplasia. J Oral Maxillofac Surg. 1984;42:735–40.CrossRef Eversole LR, Leider AS, Hansen LS. Ameloblastomas with pronounced desmoplasia. J Oral Maxillofac Surg. 1984;42:735–40.CrossRef
2.
go back to reference Barnes L, Eveson JW, Reichart P, Sidransky D. Pathology and genetics of head and neck tumours. Lyon: IARC; 2005. Barnes L, Eveson JW, Reichart P, Sidransky D. Pathology and genetics of head and neck tumours. Lyon: IARC; 2005.
3.
go back to reference Ei-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. WHO classification of head and neck tumors. Lyon: IARC; 2017. Ei-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. WHO classification of head and neck tumors. Lyon: IARC; 2017.
4.
go back to reference Shibahara T, Morita S, Sugiura K, Miniwa K, Yamaguchi A, Yamada T, et al. Epidemiological study of characteristics and treatments of ameloblastoma. J Jpn Soc Oral Oncol. 2009;21:171–81.CrossRef Shibahara T, Morita S, Sugiura K, Miniwa K, Yamaguchi A, Yamada T, et al. Epidemiological study of characteristics and treatments of ameloblastoma. J Jpn Soc Oral Oncol. 2009;21:171–81.CrossRef
5.
go back to reference Keszler A, Paparella ML, Dominguez FV. Desmoplastic and non-desmoplastic ameloblastoma: a comparative clinicopathological analysis. Oral Dis. 1996;2(3):228–31.CrossRef Keszler A, Paparella ML, Dominguez FV. Desmoplastic and non-desmoplastic ameloblastoma: a comparative clinicopathological analysis. Oral Dis. 1996;2(3):228–31.CrossRef
6.
go back to reference Li B, Long X, Wang S, Cheng Y, Chen X. Clinical and radiologic features of desmoplastic ameloblastoma. J Oral Maxillofac Surg. 2011;69(8):2173–85.CrossRef Li B, Long X, Wang S, Cheng Y, Chen X. Clinical and radiologic features of desmoplastic ameloblastoma. J Oral Maxillofac Surg. 2011;69(8):2173–85.CrossRef
7.
go back to reference Ng KH, Siar CH. Desmoplastic variant of ameloblastoma in Malaysians. Br J Oral Maxillofac Surg. 1993;31:299–303.CrossRef Ng KH, Siar CH. Desmoplastic variant of ameloblastoma in Malaysians. Br J Oral Maxillofac Surg. 1993;31:299–303.CrossRef
8.
go back to reference Beckley ML, Farhood V, Helfend LK, Alijanian A. Desmoplastic ameloblastoma of the mandible: a case report and review of the literature. J Oral Maxillofac Surg. 2002;60(2):194–8.CrossRef Beckley ML, Farhood V, Helfend LK, Alijanian A. Desmoplastic ameloblastoma of the mandible: a case report and review of the literature. J Oral Maxillofac Surg. 2002;60(2):194–8.CrossRef
9.
go back to reference Sun ZJ, Wu YR, Cheng N, Zwahlen RA, Zhao YF. Desmoplastic ameloblastoma—a review. Oral Oncol. 2009;45(9):752–9.CrossRef Sun ZJ, Wu YR, Cheng N, Zwahlen RA, Zhao YF. Desmoplastic ameloblastoma—a review. Oral Oncol. 2009;45(9):752–9.CrossRef
10.
go back to reference Araki M, Matsumoto N, Honda K, Komiyama K. Ameloblastoma, desmoplastic type: a case report with characteristic radiological presentation. Oral Radiol. 2012;28:70–3.CrossRef Araki M, Matsumoto N, Honda K, Komiyama K. Ameloblastoma, desmoplastic type: a case report with characteristic radiological presentation. Oral Radiol. 2012;28:70–3.CrossRef
11.
go back to reference Waldron CA. el-Mofty SK: A histopathologic study of 116 ameloblastomas with special reference to the desmoplastic variant. Oral Surg Oral Med Oral Pathol. 1987;63:441–51.CrossRef Waldron CA. el-Mofty SK: A histopathologic study of 116 ameloblastomas with special reference to the desmoplastic variant. Oral Surg Oral Med Oral Pathol. 1987;63:441–51.CrossRef
12.
go back to reference Luo J, You M, Zheng G, Xu L. Cone beam computed tomography signs of desmoplastic ameloblastoma: review of 7 cases. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014;118:126–33.CrossRef Luo J, You M, Zheng G, Xu L. Cone beam computed tomography signs of desmoplastic ameloblastoma: review of 7 cases. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014;118:126–33.CrossRef
13.
go back to reference Dunfee BL, Sakai O, Pistey R, Gohel A. Radiologic and pathologic characteristics of benign and malignant lesions of the mandible. Radiographics. 2006;26(6):1751–68.CrossRef Dunfee BL, Sakai O, Pistey R, Gohel A. Radiologic and pathologic characteristics of benign and malignant lesions of the mandible. Radiographics. 2006;26(6):1751–68.CrossRef
14.
go back to reference Kato H, Nomura J, Matsumura Y, Tagawa T. A case of desmoplastic ameloblastoma occupying maxillary sinus. Contemp Clin Dent. 2011;2(3):234–6.CrossRef Kato H, Nomura J, Matsumura Y, Tagawa T. A case of desmoplastic ameloblastoma occupying maxillary sinus. Contemp Clin Dent. 2011;2(3):234–6.CrossRef
15.
go back to reference Tom Thompson IO, van Rensburg LJ, Phillips VM. Desmoplastic ameloblastoma: correlative histopathology, radiology and CT-MR imaging. J Oral Pathol Med. 1996;25(7):405–10.CrossRef Tom Thompson IO, van Rensburg LJ, Phillips VM. Desmoplastic ameloblastoma: correlative histopathology, radiology and CT-MR imaging. J Oral Pathol Med. 1996;25(7):405–10.CrossRef
16.
go back to reference Dogheim OY, Hamid AE, Barakat MS, Eid M, El-Sayed SM. Role of novel magnetic resonance imaging sequences in characterization of ovarian masses. Egypt J Radiol Nucl Med. 2014;45(1):237–51.CrossRef Dogheim OY, Hamid AE, Barakat MS, Eid M, El-Sayed SM. Role of novel magnetic resonance imaging sequences in characterization of ovarian masses. Egypt J Radiol Nucl Med. 2014;45(1):237–51.CrossRef
17.
go back to reference Minami M, Kaneda T, Ozawa K, Yamamoto H, Itai Y, Ozawa M, Yoshikawa K, et al. Cystic lesions of the maxillomandibular region: MR imaging distinction of odontogenic keratocysts and ameloblastomas from other cysts. AJR Am J Roentgenol. 1996;166(4):943–9.CrossRef Minami M, Kaneda T, Ozawa K, Yamamoto H, Itai Y, Ozawa M, Yoshikawa K, et al. Cystic lesions of the maxillomandibular region: MR imaging distinction of odontogenic keratocysts and ameloblastomas from other cysts. AJR Am J Roentgenol. 1996;166(4):943–9.CrossRef
Metadata
Title
Desmoplastic ameloblastoma of the jaw: CT and MR imaging findings
Authors
Akira Baba
Hiroya Ojiri
Manabu Minami
Takashi Hiyama
Mitsuru Matsuki
Tazuko K. Goto
Satoshi Tatsuno
Kazuhiko Hashimoto
Yumi Okuyama
Nobuhiro Ogino
Hideomi Yamauchi
Takuji Mogami
Publication date
01-01-2020
Publisher
Springer Singapore
Published in
Oral Radiology / Issue 1/2020
Print ISSN: 0911-6028
Electronic ISSN: 1613-9674
DOI
https://doi.org/10.1007/s11282-019-00385-2

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