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Quality of Life Research
Published in: Quality of Life Research 7/2019

Open Access 01-07-2019 | Central Nervous System Trauma

The added value of the EQ-5D with a cognition dimension in injury patients with and without traumatic brain injury

Authors: A. J. L. M. Geraerds, Gouke J. Bonsel, Mathieu F. Janssen, M. A. de Jongh, Inge Spronk, Suzanne Polinder, Juanita A. Haagsma

Published in: Quality of Life Research | Issue 7/2019

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Abstract

Purpose

This study investigated the psychometric gain, if any, from the extension of the EQ-5D with a cognition bolt-on (EQ-5D + C) in a large cohort injury patients with and without traumatic brain injury (TBI).

Methods

Hospitalized adult injury patients filled out a survey 1 month after initial admission. The survey included the EQ-5D-3L, the cognition bolt-on item in EQ-5D format, and the visual analogue scale (EQ-VAS). We compared ceiling and other distributional effects between EQ-5D and EQ-5D + C and TBI and non-TBI group, and assessed convergent validity using the predictive association with EQ-VAS. Also, we assessed explanatory power using regression analysis, and classification efficiency using Shannon indices.

Results

In total, 715 TBI patients and 1978 non-TBI patients filled out the EQ-5D + C and EQ-VAS. Perfect health was reported by 7.9% (N = 214) on the EQ-5D, and 7.3% (N = 197) on the EQ-5D + C. Convergent validity was highest for EQ-5D + C in the TBI group (Spearman’s rank correlation coefficient = − 0.736) and lowest for EQ-5D in the non-TBI group (Spearman’s rank correlation coefficient = − 0.652). For both TBI and non-TBI groups, the explanatory power of EQ-5D + C was slightly higher than of EQ-5D (R2 = 0.56 vs. 0.53 for TBI; R2 = 0.47 vs. 0.45 for non-TBI). Absolute classification efficiency was higher for EQ-5D + C than for EQ-5D in both TBI groups, whereas relative classification efficiency was similar.

Conclusions

Psychometric performance in general of both the EQ-5D and EQ-5D + C was better in TBI patients. Adding a cognitive bolt-on slightly improved the psychometric performance of the EQ-5D-3L.
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Metadata
Title
The added value of the EQ-5D with a cognition dimension in injury patients with and without traumatic brain injury
Authors
A. J. L. M. Geraerds
Gouke J. Bonsel
Mathieu F. Janssen
M. A. de Jongh
Inge Spronk
Suzanne Polinder
Juanita A. Haagsma
Publication date
01-07-2019
Publisher
Springer International Publishing
Published in
Quality of Life Research / Issue 7/2019
Print ISSN: 0962-9343
Electronic ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-019-02144-6

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