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Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2007

Open Access 01-12-2007 | Research

Performance of the EQ-5D and the EQ-5D+C in elderly patients with cognitive impairments

Authors: Claire AG Wolfs, Carmen D Dirksen, Alfons Kessels, Daniëlle CM Willems, Frans RJ Verhey, Johan L Severens

Published in: Health and Quality of Life Outcomes | Issue 1/2007

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Abstract

Background

The EQ-5D is a reliable tool for measuring Health-Related Quality of Life (HRQoL). However, concern has been expressed that it may ignore elements of HRQoL, particularly cognition. In response to this concern, the EQ-5D has been extended with a cognitive dimension (EQ-5D+C). The aim of this study was to compare the performance of the EQ-5D and the EQ-5D+C in elderly patients with cognitive impairments by assessing their construct validity and responsiveness.

Methods

Data from the MEDICIE study (n = 196) were used, in which all questionnaires were rated by proxies.

Results

Regarding construct validity, we found similar correlations between the EQ-5D and the Mini Mental State Examination (MMSE) and between the EQ-5D+C and the MMSE. Furthermore, both the EQ-5D and the EQ-5D+C were responsive to changes in the MMSE, with the EQ-5D performing slightly better.

Conclusion

We conclude that the EQ-5D performs well for evaluating HRQoL in a population with cognitive impairments. Based on the results of this explorative study, it does not seem necessary to adjust the current classification system by adding a cognitive dimension. However, in order to compare both instruments regarding utility values, it is necessary to develop a new scoring algorithm for the EQ-5D+C by conducting a general population study. Considering the explorative nature of this study, it is recommended that more aspects of the validity of both the EQ-5D and the EQ-5D+C are explored in patients with cognitive impairments using a more tailored study design.
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Metadata
Title
Performance of the EQ-5D and the EQ-5D+C in elderly patients with cognitive impairments
Authors
Claire AG Wolfs
Carmen D Dirksen
Alfons Kessels
Daniëlle CM Willems
Frans RJ Verhey
Johan L Severens
Publication date
01-12-2007
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2007
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/1477-7525-5-33

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