Published in:
01-05-2010
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Published in: Journal of Clinical Immunology | Special Issue 1/2010
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Background
Chronic inflammatory demyelinating polyradiculoneuropathy is a chronic progressive or relapsing and remitting disease with a prevalence of up to 8.9 per 100,000.
Methods
This review discusses possible mechanisms, none of which are proven, and describes the evidence for its treatment.
Results
Cochrane Reviews provide evidence that corticosteroids, intravenous immunoglobulin, and plasma exchange are effective short-term treatments. Attempts to confirm the efficacy of other immunosuppressant agents have not been successful, although they are often used in people whose disease is resistant to the first-line treatments.
Conclusions
More and better trials are needed.